Search results for "Muscle tissue"
showing 10 items of 55 documents
Autoimmune endocrine ophthalmopathy and retrobulbar antigens.
1995
Endocrine Ophthalmopathy (EO) is based on autoimmune processes that lead to lymphocyte infiltration of the retrobulbar space. In this study, antigenic character of retrobulbar adipose, connective and muscle tissue as well as of cultured fibroblasts and myoblasts were examined. Samples were obtained from EO patients (n = 13, 8 fem., age 26-82 years, median 47 years) undergoing orbital decompression surgery. Retrobulbar and abdominal tissue from 7 controls (4 fem., 48 - 74 y) was investigated, too. Tissues were homogenized and the proteins were separated by SDS-PAGE according to molecular weight. In order to recover the separated proteins in soluble form, an electroelution technique was emplo…
l-Carnitine l-tartrate supplementation favorably affects biochemical markers of recovery from physical exertion in middle-aged men and women.
2009
The purpose of this study was to examine the effects of Carnipure tartrate (Lonza, Allendale, NJ) supplementation (total dose of 2 g/d of l-carnitine) on markers of performance and recovery from physical exertion in middle-aged men and women. Normally active and healthy men (n = 9, 45.4 +/- 5.3 years old) and women (n = 9, 51.9 +/- 5.0 years old) volunteered to participate in the investigation. Double-blind, placebo, balanced treatment presentation and crossover design were used with 3 weeks and 3 days of supplementation followed by a 1-week washout period before the other counterbalanced treatment was initiated. After 3 weeks of each supplementation protocol, each participant then performe…
A Research Agenda: The Changing Relationship Between Body Weight and Health in Aging
2008
It is increasingly recognized that changes in weight and body composition with age are strongly connected with health status and physical function. Aging is typically associated with reductions in total and lean mass, so that in the last few years of life, older people frequently report having lost weight and strength (1–3). We know only a few important facts about this process. On average, muscle mass declines with age, and even in older persons with stable weight, muscle is replaced by fat over time (4,5). Increasing fatty infiltration of muscle tissue is associated with decreasing muscle strength (6). The general pattern of weight change over the lifetime is that weight increases through…
Effect of Prolonged Physical Training on the Development of Connective Tissues in Growing Mice
1975
A rapid progress has taken place in the field of connective tissue chemistry during recent years. The structure and metabolism of collagen, elastin, glycosaminoglycans and pro-. teoglycans of different connective tissues have been extensively investigated. One of the main observations has been that large differences exist between various connective tissues [12]. For example, four different forms of collagen have been identified. The collagens in bone, cartilage, skin and basement membrane have either different amino acid composition in the a-chains or contain one or two similar a-chains in the triple helix. The scope of the connective tissue research has been extended also to skeletal muscl…
Importance of sarcopenia parameter changes after living donor liver transplantation
2017
The systemic role of muscle tissue is strengthened by the large system of hormones, chemokines and other mediators that constitute a dense network of communication between the skeletal muscle and the liver (1,2). This, associated with the evidence of a progressive malnutrition and depletion of muscle mass in end-stage liver disease (ESLD) patients, has led many to study the role of sarcopenia and its systemic effects in this setting, and to identify it as critical risk factor for post- liver transplantation (LT) mortality (3-5). Englesbe and colleagues found a direct correlation between central sarcopenia, measured by computerized tomography (CT), the total area of the psoas muscle (psoas a…
Brominated flame retardants and toxic elements in the meat and liver of red deer (Cervus elaphus), wild boar (Sus scrofa), and moose (Alces alces) fr…
2017
In order to evaluate the contamination status of terrestrial biota in Latvia, muscle and liver tissues of red deer (Cervus elaphus), wild boar (Sus scrofa), and moose (Alces alces) were analyzed for the content of polybrominated diphenyl ethers (PBDE), hexabromocyclododecane (HBCD), tetrabromobisphenol A (TBBPA), as well as cadmium and lead. The highest mean concentrations of PBDEs (46.6pgg-1 wet weight (w.w.)), cadmium (0.95mgkg-1 w.w.), and lead (0.22mgkg-1 w.w.) were observed in the tissues of moose, while the wild boar samples contained the highest levels of HBCD, with the mean concentration equal to 264pgg-1 w.w. in muscle tissues. Generally low mean concentrations of TBBPA from 0.52 t…
An Integrated Approach for the Valorization of Sea Bass (Dicentrarchus labrax) Side Streams: Evaluation of Contaminants and Development of Antioxidan…
2021
In this study, the presence of As, Hg, Cd, Pb, and mycotoxins in sea bass side streams (muscle, head, viscera, skin, and tailfin) was evaluated as a preliminary step to assess the effect of an innovative extraction technique (Pressurized Liquid Extraction
A mild juvenile variant of type IV glycogenosis.
1992
The mild juvenile form of type IV glycogenosis, confirmed by a profound deficiency of the brancher enzyme in tissue specimens is reported from three Turkish male siblings who, foremost, suffered from chronic progressive myopathy. Muscle fibers contained polyglucosan inclusions of typical fine structure, i.e. a mixture of granular and filamentous glycogen. They reacted strongly for myophosphorylase, but were resistant to diastase. These inclusions were ubiquitinated and reacted with antibody KM-279 which previously has been shown to bind to Lafora bodies, corpora amylacea and polyglucosan material in hepatic and cardiac cells of type IV glycogenosis as well as polyglucosan body myopathy with…
2021
Introduction (Neo-)adjuvant chemotherapy for breast cancer has a deleterious impact on muscle tissue resulting in reduced cardiorespiratory fitness, skeletal muscle mass and function. Physical exercise during treatment may counteract some of these negative effects. However, the effects of resistance training (RT) alone have never been explored. The present study aims to investigate if heavy-load RT during (neo-)adjuvant chemotherapy counteracts deleterious effects on skeletal muscle in women diagnosed with breast cancer. We hypothesize that (neo-)adjuvant treatment with chemotherapy will reduce muscle fiber size, impair mitochondrial function, and increase indicators of cellular stress and …
Respiratory Gas Transport in Heart
1973
The purpose of this paper is to describe an attempt to obtain a better understanding of the dynamics of the oxygen supply of the myocardium under physiological and pathophysiological conditions by examining the oxygen diffusion in the heart muscle tissue during systole and diastole. In comparison to other organs the oxygen supply of the myocardium is characterized by a number of specific features. The most important one is that the gas exchange in the myocardium is a nonsteady-state diffusion process.