Search results for "Muscle"

Corrigendum to “Increased cross-education of muscle strength and reduced corticospinal inhibition following eccentric strength training” [Neuroscienc…

2015

Assessment of muscle strength and muscle function in fibromyalgia

2014

Exercise restores decreased physical activity levels and increases markers of autophagy and oxidative capacity in myostatin/activin blocked mdx mice

2013

The importance of adequate levels of muscle size and function and physical activity is widely recognized. Myostatin/activin blocking increases skeletal muscle mass but may decrease muscle oxidative capacity and can thus be hypothesized to affect voluntary physical activity. Soluble activin receptor IIB (sActRIIB-Fc) was produced to block myostatin/activins. Modestly dystrophic mdx mice were injected with sActRIIB-Fc or PBS with or without voluntary wheel running exercise for 7 wk. Healthy mice served as controls. Running for 7 wk attenuated the sActRIIB-Fc-induced increase in body mass by decreasing fat mass. Running also enhanced/restored the markers of muscle oxidative capacity and autoph…

2019

Muscle architecture is an important component of muscle function, and recent studies have shown changes in muscle architecture with fatigue. The stretch-shortening cycle is a natural way to study human locomotion, but little is known about how muscle architecture is affected by this type of exercise. This study investigated potential changes in medial gastrocnemius (MG) muscle architecture after exhaustive stretch-shortening cycle exercise. Male athletes (n = 10) performed maximal voluntary contractions (MVC) and maximal drop jump (DJ) tests before and after an exercise task consisting of 100 maximal DJs followed by successive rebound jumping to 70% of the initial maximal height. The exerci…

Conditioning effect of transcranial magnetic stimulation evoking motor‐evoked potential on V‐wave response

2014

Abstract The aim of this study was to examine the collision responsible for the volitional V‐wave evoked by supramaximal electrical stimulation of the motor nerve during voluntary contraction. V‐wave was conditioned by transcranial magnetic stimulation (TMS) over the motor cortex at several inter‐stimuli intervals (ISI) during weak voluntary plantar flexions (n = 10) and at rest for flexor carpi radialis muscle (FCR; n = 6). Conditioning stimulations were induced by TMS with intensity eliciting maximal motor‐evoked potential (MEPmax). ISIs used were ranging from −20 to +20 msec depending on muscles tested. The results showed that, for triceps surae muscles, conditioning TMS increased the V‐…

Increased mRNAs for procollagens and key regulating enzymes in rat skeletal muscle following downhill running.

1999

The purpose of the study was to investigate pre-translational regulation of collagen expression after a single bout of exercise. We analysed steady-state messenger ribonucleic acid (mRNA) levels for collagen types I, III and IV, alpha- and beta-subunits of prolyl 4-hydroxylase and lysyl oxidase (enzymes modifying procollagen chains), and enzyme activity of prolyl 4-hydroxylase from rat soleus muscle (MS) and the red parts of quadriceps femoris muscle (MQF) after 12 h and after 1, 2, 4, 7 and 14 days of downhill (-13.5 degrees ) treadmill running at a speed of 17 m.min-1 for 130 min. Histological and biochemical assays revealed exercise-induced muscle damage in MQF but not MS. Steady-state m…

Antidepressant Effects of Exercise: A Role for the Adiponectin-PGC-1α-kynurenine Triad?

2015

It is well-recognized that exercise improves mental health, e.g., by decreasing depressive behaviors, improving hippocampal-dependent learning and neurogenesis, and increasing dendritic plasticity. Yet how exercise influences the brain at the molecular level is not clearly understood. Yau et al recently reported that the antidepressant effects of physical exercise are mainly mediated by adiponectin, an adipocyte-secreted hormone ('adipocytokine') with neuroprotective effects at the central nervous system level (Yau et al., 2014). 4.155 JCR (2015) Q1, 12/83 Physiology; Q2, 63/187 Cell biology UEM

Effects of dopamine in isolated rat colon strips.

2005

The aim of the present work is to investigate the effects of dopamine on isolated rat colon strips, and whether dopamine receptors are involved in these effects. Experiments on spontaneous motility and under potassium contraction were performed with dopamine and isoprenaline, both in the absence and presence of antagonists (distal colon strips, isotonic recording, Tyrode solution, 31 °C, 1 g of resting tension). At higher concentration (10–4mol/L), dopamine abolished spontaneous motility of the rat colon and this effect was not modified by antagonists. In isolated rat colon strips that were depolarized with potassium, dopamine produced concentration-dependent relaxation, without significant…

Changes induced by eccentric training on force-velocity relationships of the elbow flexor muscles.

1995

The aim of this study was to examine the effects of a short term eccentric training period on force-velocity relationships of the elbow flexor muscles. From a muscle model, the maximal shortening velocity Vo(x) and the af parameter which varies according to the curvature of the force-velocity relationship of the muscle were determined. Sixteen volunteer subjects divided into 2 groups participated in this study (Group Eccentric GE, n = 8; Group Control GC, n = 8). The subjects performed, on an isokinetic ergometer, 2 maximal concentric elbow flexions at different angular velocities (60, 120, 180, 240, 300, 360 degrees s-1) and held maximal and submaximal isometric actions at an elbow flexion…

Substance P inactivation by transglutaminase in vitro.

1992

Gamma(glutamyl5)spermine derivative of substance P (Spm-SP) was synthesized in vitro in the presence of purified guinea pig liver transglutaminase and Ca2+. The spermine adduct of the neuropeptide was purified by HPLC on a reversed-phase column and characterized by fast atom bombardment mass spectrometry. The biological activities of Spm-SP were tested by assaying, in comparison with substance P, its ability to induce both the contractions of smooth muscle in vitro and the edema formation in vivo. Spm-SP was shown not to elicit contractile responses in the isolated rat stomach strip and duodenum and not to antagonize the spasmogenic effect evoked by the native neuropeptide. Furthermore, Spm…