Search results for "Myc"
showing 10 items of 3773 documents
Validation and application of a PCR primer set to quantify fungal communities in the soil environment by real-time quantitative PCR
2011
Fungi constitute an important group in soil biological diversity and functioning. However, characterization and knowledge of fungal communities is hampered because few primer sets are available to quantify fungal abundance by real-time quantitative PCR (real-time Q-PCR). The aim in this study was to quantify fungal abundance in soils by incorporating, into a real-time Q-PCR using the SYBRGreen (R) method, a primer set already used to study the genetic structure of soil fungal communities. To satisfy the real-time Q-PCR requirements to enhance the accuracy and reproducibility of the detection technique, this study focused on the 18S rRNA gene conserved regions. These regions are little affec…
MONITORING AND USE OF ANTIMYCOTICS FOR SYSTEMIC USE SUPPLIED BY THE STATE HOSPITAL PHARMACY OF MARSALA (TP), ITALY: MYCAMINE® (MICAFUNGIN)
2014
Micafungin is an antimycotic drug and represents an important addition to the available therapies for the treatment of systemic fungal infections. Micafungin is used in the treatment of invasive candidiasis, oesophageal and prophylaxis of Candida infections. It inhibits, in a non-competitive way, the synthesis of 1,3-b-D-glucan, a component of fungal cell wall and is rapidly distributed into the tissues. It has a high-rate bond with respect to plasma protein; the above mentioned bond is independent from the concentration of the drug. It is metabolized through the liver, being not subject to intense metabolic transformations until the excretion. There is no evidence of systemic accumulation …
Bovine lactoferrin prevents invasive fungal infections in very low birth weight infants: a randomized controlled trial.
2011
Background: Lactoferrin is a mammalian milk glycoprotein involved in innate immunity. Recent data show that bovine lactoferrin (bLF) prevents late-onset sepsis in preterm very low birth weight (VLBW) neonates. Methods: This is a secondary analysis of data from a multicenter randomized controlled trial where preterm VLBW neonates randomly received bLF (100 mg/day; group A1), bLF + Lactobacillus rhamnosus GG (106 colony-forming units per day; group A2), or placebo (group B) for 6 weeks. Here we analyze the incidence rates of fungal colonization, invasive fungal infection (IFI), and rate of progression from colonization to infection in all groups. Results: This study included 472 neonates who…
Aromatic aminoacids and Calcium Dependent Antibiotic:Relation of primary metabolism to antibiotic production in Actinomycetes
2007
Molecular and agronomic responses to soil inoculation with plant-growth promoting rhizobacteria and arbuscular mycorrhizae in Triticum durum
2012
Plant-growth promoting rhizobacteria (PGPR) and arbuscular mycorrhizal (AM) fungi contribute to plant nutrient uptake by increasing the availability of nutrients and the root adsorbing surface. However, the molecular mechanisms of plant responses to these associations are still under-investigated. Gene expression analysis could lead to the identification of biomarkers usable to early select genotypes for an increased nutrient uptake efficiency. The main objective of this study was to determine the effects of these associations on plant total biomass and grain yield in durum wheat (cv. Anco Marzio). Secondly, we aimed to analyze the expression pattern of key genes involved in nutrient uptake…
Differential Contribution of the Parental Genomes to a
2019
In European regions of cold climate, S. uvarum can replace S. cerevisiae in wine fermentations performed at low temperatures. S. uvarum is a cryotolerant yeast that produces more glycerol, less acetic acid and exhibits a better aroma profile. However, this species exhibits a poor ethanol tolerance compared with S. cerevisiae. In the present study, we obtained by rare mating (non-GMO strategy), and a subsequent sporulation, an interspecific S. cerevisiae × S. uvarum spore-derivative hybrid that improves or maintains a combination of parental traits of interest for the wine industry, such as good fermentation performance, increased ethanol tolerance, and high glycerol and aroma productions. G…
Visually induced motion sickness and presence in videogames: The role of sound
2012
Visually induced motion sickness (VIMS) is a well-known phenomenon in virtual environments, simulators, and videogames. We conducted an experiment to analyze the role of sound on the severity of VIMS and the feeling of presence in videogames. Thirty-two subjects first watched a pre-recorded sequence of the game “Mirrors Edge” and then played the game actively. Game-play sound was activated for half of the participants. VIMS was measured via the Simulator Sickness Questionnaire and the Fast Motion Sickness Scale, presence was captured using the Presence Questionnaire. Results showed severe VIMS in all participants during the passive video session, whereas active-play revealed only moderate …
The discovery of a Mycenaean-type tholos tomb in the Bronze Age necropolis of the Gazzi buried floodplain (Messina, Southern Italy): new geological a…
2019
This paper deals with a monument that is, up to this date, unique in Sicily and in the Italian peninsula: the Mycenaean-type tholos tomb of the Gazzi necropolis in Messina. A recent excavation in the alluvial deposits revealed extensive traces of a funerary area with a tholos tomb and several enchytrismos tombs with skeletal remains, presumably dated back to the end of the Early or the initial stage of the Middle(?) Bronze Age. The present multi-disciplinary investigation has been developed to analyse new data related to sediments, building stones and skeletal remains of this funerary area. The stratigraphic succession hosting the necropolis was formed by overbank sediments deposited on the…
Glicerīna cikla ietekme uz maizes rauga šūnu fenotipu
2017
Šī darba mērķis bija novērtēt redoks kofaktora NADPH inženierijas mēģinājuma ietekmi uz rekombinantu Saccharomyces cerevisiae celmu fenotipu eksponenciālās augšanas laikā. Šajos CEN.PK2-1C rekombinantajos celmos tika ekspresēta NADP+ atkarīga glicerīna dehidrogenāze (Gld2p) ar mērķi atgriezt daļu glicerīna glikolīzē, kombinācijā ar glutationa antioksidatīvās sistēmas un NADPH kofaktora reģenerāciju. Rekombinantajiem celmiem tika noteikta subletālo stresu noturība, NADPH/NADP+ kofaktora un GSH/GSSG savstarpējās relatīvās attiecības, izmantojot spektrofotometriju un fluorometriju, kā arī rekombinantu augšanas dinamika ar ksilozi kā vienīgo oglekļa avotu. Darbā novērots, ka izveidotais „glicer…