Search results for "NEB"
showing 10 items of 543 documents
Pyhä Nikolaos ihmeidentekijä : ikonografian kehitttyminen bysanttilaisessa ja venäläisessä ikonitaiteessa : teosanalyysi Sinebrycoffin ikonista mater…
1999
Observatory science with eXTP
2019
Disponible preprint en: arXiv:1812.04023v1 [astro-ph.HE] [v1] Mon, 10 Dec 2018 19:00:52 UTC (4,376 KB)
CCDC 886202: Experimental Crystal Structure Determination
2013
Related Article: V.N.Dokorou, C.J.Milios, A.C.Tsipis, M.Haukka, P.G.Weidler, A.K.Powell, G.E.Kostakis|2012|Dalton Trans.|41|12501|doi:10.1039/c2dt31383a
CCDC 216906: Experimental Crystal Structure Determination
2004
Related Article: C.L.M.Pereira, E.F.Pedroso, H.O.Stumpf, M.A.Novak, L.Ricard, R.Ruiz-Garcia, E.Riviere, Y.Journaux|2004|Angew.Chem.,Int.Ed.|43|956|doi:10.1002/anie.200352604
CCDC 819588: Experimental Crystal Structure Determination
2012
Related Article: J.Ferrando-Soria, R.Ruiz-Garcia, J.Cano, S.-E.Stiriba, J.Vallejo, I.Castro, M.Julve, F.Lloret, P.Amoros, J.Pasan, C.Ruiz-Perez, Y.Journaux, E.Pardo|2012|Chem.-Eur.J.|18|1608|doi:10.1002/chem.201103308
CCDC 1896308: Experimental Crystal Structure Determination
2019
Related Article: Arun Pal, Santanu Chand, Joan Cano Boquera, Francesc Lloret, Jian-Bin Lin, Shyam Chand Pal, Madhab C. Das|2019|Inorg.Chem.|58|6246|doi:10.1021/acs.inorgchem.9b00471
l-Valine biosynthesis during batch and fed-batch cultivations of Corynebacterium glutamicum: Relationship between changes in bacterial growth rate an…
2007
Abstract A transition in the bacterial growth rate to below maximum was found to be an optimum parameter of cellular physiology to increase the activity of acetohydroxy acid synthase, a regulatory enzyme in l -valine synthesis, and amino acid overproduction by Corynebacterium glutamicum ATCC 13032 recombinants under batch and fed-batch cultivation conditions. An increase in l -valine synthesis under transient situations when cellular growth rate was downregulated was correlated to a decrease in the activity of aconitase, a key enzyme in the tricarboxylic acid cycle (TCA) of C. glutamicum , and, in contrast, to an increase in the activity of glucose-6-phosphate dehydrogenase, a key enzyme in…
Herbicidally Active Derivatives of Aminomethylenebis-Phosphonic Acid-Mode of Action and Structure - Activity Relationship
1996
Abstract: (N-pyridylamino)methylenebisphosphonates exhibit strong herbicidal activity which may be reversed by supplementation of the growth media with aromatic amino acids. They appeare to be the inhibitors of aromatic amino acids biosynthesis acting as inhibitors of DAHP synthase the first enzyme of shikimate pathway. Over 40 analogues of these acids were synthesized in order to determine the structure-activity relationship.
Mode of action of herbicidal derivatives of aminomethylenebisphosphonic acid. Part II. Reversal of herbicidal action by aromatic amino acids
1997
The herbicidal action of N-pyridylaminomethylenebisphosphonic acids is accompanied by an impairment of anthocyanin biosynthesis. This suggests that they might act as inhibitors of some steps in aromatic amino acid biosynthesis. Herbicidal effects were reversed by aromatic amino acids using both bacterial and plant models, a finding that strongly supports this hypothesis. Structural features of these compounds suggest the sixth enzyme in the shikimate pathway 5-enol-pyruvoylshikimate-3-phosphate (EPSP) synthase as a possible target, since a strong structural similarity exists between aminomethylenebisphosphonic acid and an inhibitor of EPSP synthase, the herbicide glyphosate. This is, howeve…
Identification of Gip as a novel phage-encoded gyrase inhibitor protein featuring a broad activity profile
2021
AbstractBacteriophages represent a powerful source for the identification of novel antimicrobial proteins. In this study, a screening of small cytoplasmic proteins encoded by the CGP3 prophage of Corynebacterium glutamicum, resulted in the identification of the novel gyrase-inhibiting protein Cg1978 (Gip), which shows a direct interaction with the gyrase subunit A (GyrA). In vitro supercoiling assays further suggest a stabilization of the cleavage complex by Gip. Overproduction of Gip in C. glutamicum resulted in a severe growth defect as well as an induction of the SOS response. The cells adapted to gip overexpression by increasing expression levels of gyrAB and by reducing topA expression…