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showing 10 items of 55461 documents

Probing the guest-binding preference of three structurally similar and conformationally adaptive macrocycles.

2019

A hybrid macrocycle was synthesized by combining the repeat units in oxatub[4]arene and zorb[4]arene, and its recognition behavior and conformational analysis were studied. Three structurally similar and conformationally adaptive macrocycles show different guest-binding selectivities and preferences even in a complex mixture containing three macrocycles and three guests.

010405 organic chemistryChemistryStereochemistryMetals and AlloysGeneral Chemistry010402 general chemistry01 natural sciencesCatalysisPreference0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsMaterials ChemistryCeramics and CompositesChemical communications (Cambridge, England)
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Conformational Switching of Multi-Responsive Ferrocenyl-Phenol Conjugates

2016

Multifunctional conformational switches based on the ferrocenyl-salicylic acid amide motif with increasing additional complexity at the Fc moiety (R = COOMe, CONHEt, CONHFc; H-2–H-4; Fc = ferrocenyl) have been prepared and their preferred secondary structures in solution have been elucidated by NMR and IR spectroscopy in combination with conformational searches based on DFT calculations. Their distinct conformational responses to deprotonation ([2]––[4]–) and oxidation ([H-2]+·–[H-4]+·) have been revealed by IR, EPR, and UV/Vis spectroscopy as well as by DFT calculations. Deprotonation inverts all amide units (double amide twist) whereas oxidation selectively flips the terminal amide unit (…

010405 organic chemistryChemistryStereochemistryOrganic ChemistryInfrared spectroscopy010402 general chemistry01 natural sciences0104 chemical scienceslaw.inventionchemistry.chemical_compoundDeprotonationlawAmideMoietyPhenolPhenolsPhysical and Theoretical ChemistryElectron paramagnetic resonanceSpectroscopyEuropean Journal of Organic Chemistry
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Diferratricarbaboranes of thesubcloso-[(η5-C5H5)2Fe2C3B8H11] Type, the First Representatives of the 13-Vertex Dimetallatricarbaborane Series

2003

Treatment of the [2-Cp-9-tBuNH-closo-2,1,7,9-FeC 3 B 8 H 1 0 ] (1) ferratricarbollide (Cp = η 5 -C 5 H 5 -) with Na + C 1 0 H 8 - in 1,2-dimethoxyethane (DME) at room temperature produced an air-sensitive transient anion with a tentatively identified nido-[tBUNH-CpFeC 3 B 8 H 1 0 ] 2 - constitution. In-situ reaction of this low-stability ion with [CpFe(CO) 2 I] or [CpFe(CO) 2 ] 2 generated three violet diferratricarbaboranes identified as paramagnetic subcloso complexes [4,5-Cp 2 - -4,5,1,6,7-Fe 2 C 3 B 8 H 1 1 ] (2; yield 2%), [4,5-Cp 2 - -4,5,1,7,12-Fe 2 C 3 B 8 H 1 1 ] (3; yield 2%), and [7-tBuNH-4,5-Cp 2 - -4,5,1,7,12-Fe 2 C 3 B 8 H 1 0 ] (4; yield 14%). These first representatives of t…

010405 organic chemistryChemistryStereochemistryOrganic ChemistryInfrared spectroscopyBoranesGeneral Chemistry010402 general chemistryMass spectrometry01 natural sciencesCatalysis3. Good health0104 chemical sciencesIonlaw.inventionVertex (geometry)CrystallographyParamagnetismlawYield (chemistry)Electron paramagnetic resonanceChemistry - A European Journal
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From self-inclusion and host-guest complexes to channel structures

2012

Various supramolecular interactions are applied as driving forces in self-assembly and molecular recognition processes. Single crystal X-ray diffraction method is especially important for solid-state studies of non-covalent interactions as it reveals their influence on the molecular and supramolecular structures. This paper discusses structures of two completely different types of compounds in which a variety of intermolecular interactions are involved. It will be shown that strong and weak intermolecular hydrogen bonds in N-alkylammonium resorcinarene salts, depending on the type of anion, inclusion of resorcinarene upper rim pendant group or solvent molecules into the cavity, strongly aff…

010405 organic chemistryChemistryStereochemistryX-ray structure; supramolecular chemistry; hydrogen bonding; hydrophobic interaction; resorcinarene; palladium complexSupramolecular chemistryGeneral ChemistryInclusion (mineral)010402 general chemistryta11601 natural sciencesHost (network)0104 chemical sciencesCommunication channel
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A hybrid magnet with coexistence of ferromagnetism and photoinduced Fe(iii) spin-crossover

2011

International audience; The insertion of a [Fe(sal2-trien)]+ complex cation into a 2D oxalate network results in a hybrid magnet with coexistence of magnetic ordering and photoinduced spin-crossover (LIESST effect) in compound [FeIII(sal2-trien)][MnIICrIII(ox)3]*(CH2Cl2) (1). A complete photomagnetic characterization together with a detailed structural analysis of the low-spin (LS) and high-spin (HS) structures of 1 is presented in order to understand such unusual behavior. This very rare and unexpected property in a FeIII spin-crossover complex, has been attributed to the strong distortion exhibited by the metastable HS state. Furthermore, 1 has shown that, in contrast to what has been pre…

010405 organic chemistryChemistryStereochemistry[CHIM.MATE]Chemical Sciences/Material chemistryGeneral Chemistry010402 general chemistry01 natural sciencesLIESSTOxalate0104 chemical scienceschemistry.chemical_compoundCrystallographyFerromagnetismSpin crossoverMetastabilityMagnetSpin (physics)Chemical Science
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Asymmetric Synthesis of Spiro β-Lactamsviaa Squaramide- Catalyzed Sulfa-Michael Addition/Desymmetrization Protocol

2016

An efficient asymmetric synthesis of spirocyclohexenone β-lactams bearing three contiguous stereocenters has been achieved in moderate to good yields and high stereoselectivities. The protocol involves the combination of a squaramide-catalyzed sulfa-Michael addition under desymmetrization via a dynamic kinetic resolution of racemic 2,5-cyclohexadienones.

010405 organic chemistryChemistryStereochemistrybeta-lactamsasymmetric synthesisEnantioselective synthesisSquaramideGeneral Chemistry010402 general chemistry01 natural sciencesDesymmetrization0104 chemical sciencesKinetic resolutionStereocenterCatalysisOrganocatalysisMichael reactionta116Advanced Synthesis & Catalysis
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Aza and cyanobridged tripodal dinuclear copper(II) complexes: Electrochemical studies and structural evidence for an original azacyanocarbanion

2014

International audience; The reactivity of the mononuclear [Cu(TMPA)(L)] n+ complex (TMPA: tris(2-methylpyridine) amine, L: CH3CN, H2O) towards two different bridging species (tetracyanoethylene, 4,40-bipyridine) was investigated. The dinuclear complex [(mu-4,40-bipy)Cu-II(TMPA)(2)](CF3SO3)(4) (1) was synthesised and analysed by Xray diffraction (XRD). Magnetic studies revealed that this derivative displays very weak antiferromagnetic interactions between the two metal centres (2J = -0.69 cm(-1)). Solution studies (EPR spectroscopy and voltammetry) evidenced the lability of the bridged neutral bipyridine ligand in acetonitrile. The reaction of TCNE (TCNE: tetracyanoethylene) with the copper(…

010405 organic chemistryChemistryStereochemistrychemistry.chemical_elementCrystal structureTetracyanoethylene010402 general chemistryElectrochemistry01 natural sciencesCopper0104 chemical scienceslaw.inventionInorganic Chemistrychemistry.chemical_compoundCrystallographyBipyridinelaw[CHIM.ANAL]Chemical Sciences/Analytical chemistryMaterials ChemistryAmine gas treating[CHIM.COOR]Chemical Sciences/Coordination chemistryPhysical and Theoretical ChemistryElectron paramagnetic resonanceAcetonitrile
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Synthesis, crystal structure and magnetic properties of [Co(bpcam)2]ClO4·dmso·H2O, [Co(bpcam)2]2[Co(NCS)4]·dmso·H2O and [Ni(bpcam)2]·H2O [Hbpcam = bi…

2017

The preparation, spectroscopic characterization, structural study and magnetic investigation of three new complexes of formula [Co(bpcam)2]ClO4·dmso·H2O (1), [Co(bpcam)2]2[Co(NCS)4]·dmso·H2O (2) and [Ni(bpcam)2]·H2O (3) [Hbpcam = bis(2-pyrimidylcarbonyl)amide] are reported. Each bpcam group in 1–3 acts as a tridentate ligand being coordinated to the cobalt(III) (1 and 2)/nickel(II) (3) ions through three nitrogen atoms in a mer-arrangement. Six-coordinate cobalt(III) and nickel(II) occur in 1 and 3 respectively, whereas six-coordinate cobalt(III) and four-coordinate cobalt(II) coexist in 2. Cyclic voltammetry of 1 in acetonitrile shows the occurrence of one quasi reversible CoIII ↔ CoII pro…

010405 organic chemistryChemistryStereochemistrychemistry.chemical_elementGeneral ChemistryCrystal structureAtmospheric temperature range010402 general chemistry01 natural sciencesMagnetic susceptibilityCatalysis0104 chemical sciencesNickelCrystallographychemistry.chemical_compoundAmideMaterials ChemistryCyclic voltammetryAcetonitrileCobaltNew Journal of Chemistry
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Combining Cyanometalates and Coordination Clusters: An Alternative Synthetic Route toward Original Molecular Materials

2013

International audience; With the discovery of molecules or molecule-based compounds that can display blocked magnetization, magnetic ordering or switchable magnetic bistability, the research efforts devoted to molecular magnetic materials have considerably increased over the past two decades, fully exploiting the advantages of the bottom-up approach. 1-4 This research field focuses on promising properties for potential technological applications such as information storage, quantum computing and spintronics at the molecular scale, but it also provides fundamental insights into original quantum phenomena. 5,6 Coordination chemists have developed efficient synthetic tools for the preparation …

010405 organic chemistryChemistryStereochemistrychemistry.chemical_elementGeneral ChemistryTrigonal crystal system010402 general chemistryCondensed Matter Physics01 natural sciencesCopper0104 chemical sciencesCoordination networkCluster (physics)[CHIM]Chemical SciencesGeneral Materials Science[CHIM.COOR]Chemical Sciences/Coordination chemistryMolecular materials
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Protonation of Tyrosine Kinase Inhibitor Lapatinib: A Theoretical and Experimental Study

2019

The protonation process of tyrosine kinase inhibitor lapatinib was studied by means of 1HNMR and UV/Vis spectroscopy joint with the theoretical calculations at DFT and semi-empirical levels. DFT/M06-2X geometries were used to describe and compare the different cationic forms of lapatinib, while ZINDO/S-CI method performed on those geometries allowed for the interpretation of experimental UV/Vis spectra of lapatinib at various pH. We found that at low pH two different dicationic forms (N2N1 and N1N3) of lapatinib were present in ethanol and DMSO-d6 solutions. The first protonation, however, occurred on the aliphatic N1 in DMSO-d6, while in ethanol solutions most probably the quinazoline nitr…

010405 organic chemistryChemistryStereochemistrymedicine.drug_classMechanical EngineeringProtonationNuclear magnetic resonance spectroscopy010402 general chemistryLapatinib01 natural sciencesTyrosine-kinase inhibitor0104 chemical sciencesUltraviolet visible spectroscopyMechanics of MaterialsmedicineGeneral Materials Sciencemedicine.drugKey Engineering Materials
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