Search results for "NEUROSCIENCE"

Test-retest reliability of motor-evoked potentials at 20% and 60% of maximum isometric voluntary contraction in rectus femoris muscle

2023

Closed-Loop Acoustic Stimulation During Sleep in Children With Epilepsy: A Hypothesis-Driven Novel Approach to Interact With Spike-Wave Activity and …

2019

Slow waves, the electroencephalographic (EEG) hallmark of deep sleep, can be systematically manipulated by acoustic stimulation: stimulation time-locked to the down phase of slow waves reduces, whereas stimulation time-locked to the up phase increases slow waves. Spike-waves during sleep seem to be related to slow waves, raising the question of whether spike-waves can be systematically influenced by such acoustic stimulation. In five pediatric patients, all-night EEG was recorded, combined with real-time slow wave detection. Throughout the night, acoustic stimulation was performed in a 3 × 5-min-block design (no stimulation—stimulation—no stimulation). Tones were applied time-locked either …

Cannabinoid 1/2 Receptor Activation Induces Strain-Dependent Behavioral and Neurochemical Changes in Genetic Absence Epilepsy Rats From Strasbourg an…

2022

Childhood absence epilepsy (CAE) is characterized by absence seizures, which are episodes of lack of consciousness accompanied by electrographic spike-wave discharges. About 60% of children and adolescents with absence seizures are affected by major neuropsychological comorbidities, including anxiety. Endocannabinoids and monoamines are likely involved in the pathophysiology of these CAE psychiatric comorbidities. Here, we show that the synthetic cannabinoid receptor type 1/2 (CB1/2R) agonist WIN 55,212-2 (2 mg/kg) has a strain-dependent effect on anxiety-like and motor behavior when assess in the hole board test and cerebral monoaminergic levels in Genetic Absence Epilepsy Rats from Strasb…

Most hippocampal CA1 pyramidal cells in rabbits increase firing during awake sharp-wave ripples and some do so in response to external stimulation an…

2020

Hippocampus forms neural representations of real-life events including multimodal information of spatial and temporal context. These representations, i.e. organized sequences of neuronal firing are repeated during following rest and sleep, especially when so-called sharp-wave ripples (SPW-Rs) characterize hippocampal local-field potentials. This SPW-R –related replay is thought to underlie memory consolidation. Here, we set out to explore how hippocampal CA1 pyramidal cells respond to the conditioned stimulus during trace eyeblink conditioning and how these responses manifest during SPW-Rs in awake adult female New Zealand White rabbits. Based on reports in rodents, we expected SPW-Rs to ta…

Olfactory and cortical projections to bulbar and hippocampal adult-born neurons

2015

New neurons are continually generated in the subependymal layer of the lateral ventricles and the subgranular zone of dentate gyrus during adulthood. In the subventricular zone, neuroblasts migrate a long distance to the olfactory bulb where they differentiate into granule or periglomerular interneurons. In the hippocampus, neuroblasts migrate a short distance from the subgranular zone to the granule cell layer of the dentate gyrus to become granule neurons. In addition to the short-distance inputs, bulbar interneurons receive long-distance centrifugal afferents from olfactory-recipient structures. Similarly, dentate granule cells receive differential inputs from the medial and lateral ento…

Évaluation du jugement temporel après l'introduction d'un stimulus émotionnel de nature olfactive : apport dans le diagnostic différentiel entre la m…

2014

Revue non indexée dans le JCR.; La multiplicité des termes et des théories concernant les émotions rend leur évaluation particulièrement complexe. La majorité des évaluations actuelles ne prend en compte que l’expérience psychique de l’individu et omet la part implicite des processus émotionnels. Les procédures d’amorçage permettent d’étudier ce type de traitement inconscient. En nous appuyant sur les paradigmes d’amorçage affectif et les modèles d’horloge interne, nous avons élaboré un paradigme d’amorçage émotionnel. Il consiste en une tâche de jugement temporel après l’introduction d’un stimulus émotionnel. En temps normal, l’introduction d’un tel stimulus va créer une activation de l’ho…

Current Status on the Functional Characterization of Chemosensory Receptors of Cydia pomonella (Lepidoptera: Tortricidae)

2018

Cydia pomonella (Lepidoptera: Tortricidae) is a major pest of apple, pear and walnuts. For its control, alternative strategies targeting the olfactory system, like mating disruption, have been combined with insecticide applications. The efficacy of these strategies headed the direction of efforts for the functional characterization of codling moth chemosensory receptors to implement further control methods based on chemical sensing. With the advent of transcriptomic analysis, partial and full-length coding sequences of chemosensory receptors have been identified in antennal transcriptomes of C. pomonella. Extension of partial coding sequences to full-length by polymerase chain reaction (PCR…

Vesiclepedia:A Compendium for Extracellular Vesicles with Continuous Community Annotation

2012

Vesiclepedia is a community-annotated compendium of molecular data on extracellular vesicles.

Longitudinal profiles of mental well-being as correlates of successful aging in middle age

2017

This study analyzed the multidimensional (including emotional, psychological, and social well-being) profiles of mental well-being and their links to various indicators of successful aging (SA; including diseases, cognitive and physical function, and engagement with life). The analyses were based on the Finnish Jyväskylä Longitudinal Study of Personality and Social Development, where the age-cohort participants have been followed from age 8 to 50. Data on 335 participants collected in mid-adulthood were analyzed. Applying Latent Profile Analysis and measures of life satisfaction and psychological well-being at ages 36, 42, and 50 and social well-being at ages 42 and 50, four longitudinal w…

“The Best Laid Plans” : Do Individual Differences in Planfulness Moderate Effects of Implementation Intention Interventions?

2022

While there is good evidence supporting the positive effect of planning strategies like implementation intentions on the relationship between intention and behavior, there is less evidence on the moderating role of individual differences in planning capacity on this effect. This study aimed to examine the role of individual differences in planfulness on the effect of planning strategies on the intention–behavior gap. Specifically, this study investigated the influence of planfulness on the effectiveness of implementation intentions on goal-directed behavior using an experimental design. Undergraduate university students (N = 142) with high and low levels of planfulness based on a priori sco…