Search results for "NODD"

showing 3 items of 3 documents

Characterizing microstructural tissue properties in multiple sclerosis with diffusion MRI at 7 T and 3 T: The impact of the experimental design

2019

The recent introduction of advanced magnetic resonance (MR) imaging techniques to characterize focal and global degeneration in multiple sclerosis (MS), like the Composite Hindered and Restricted Model of Diffusion, or CHARMED, diffusional kurtosis imaging (DKI) and Neurite Orientation Dispersion and Density Imaging (NODDI) made available new tools to image axonal pathology non-invasively in vivo. These methods already showed greater sensitivity and specificity compared to conventional diffusion tensor-based metrics (e.g., fractional anisotropy), overcoming some of its limitations. While previous studies uncovered global and focal axonal degeneration in MS patients compared to healthy contr…

0301 basic medicineTime FactorsUltra-high field MRIAxonal pathologyCohort Studies0302 clinical medicineNuclear magnetic resonancemethods [Diffusion Magnetic Resonance Imaging]MicrostructureNODDImedicine.diagnostic_testGeneral NeuroscienceWATER DIFFUSIONmedicine.anatomical_structureResearch DesignKurtosisMulti-shell diffusion MRIAxonal degenerationWHITE-MATTERTENSORAdultMaterials sciencetherapy [Multiple Sclerosis]Sensitivity and SpecificityWhite matterMultiple sclerosis03 medical and health sciencesFractional anisotropyImage Interpretation Computer-Assistedmedicinediagnostic imaging [Nerve Degeneration]Journal ArticleHumansddc:610OPTIMIZATIONMultiple sclerosisinstrumentation [Diffusion Magnetic Resonance Imaging]diagnostic imaging [Multiple Sclerosis]Magnetic resonance imagingQUANTIFICATIONmedicine.diseaseMODELPATHOLOGYDiffusion Magnetic Resonance Imaging030104 developmental biologyRESOLUTIONDENSITYNerve Degeneration030217 neurology & neurosurgeryDiffusion MRI
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Linking Microstructural Integrity and Motor Cortex Excitability in Multiple Sclerosis

2021

Motor skills are frequently impaired in multiple sclerosis (MS) patients following grey and white matter damage with cortical excitability abnormalities. We applied advanced diffusion imaging with 3T magnetic resonance tomography for neurite orientation dispersion and density imaging (NODDI), as well as diffusion tensor imaging (DTI) in 50 MS patients and 49 age-matched healthy controls to quantify microstructural integrity of the motor system. To assess excitability, we determined resting motor thresholds using non-invasive transcranial magnetic stimulation. As measures of cognitive-motor performance, we conducted neuropsychological assessments including the Nine-Hole Peg Test, Trail Makin…

Malemedicine.medical_treatmentNeuropsychological Testsmultiple sclerosisDisability EvaluationImmunology and AllergyGray MatterMotor skillOriginal ResearchNODDIMotor CortexMiddle AgedTranscranial Magnetic StimulationWhite Mattermedicine.anatomical_structureDiffusion Tensor Imagingtract-based spatial statisticsCardiologyFemalePrimary motor cortexneurite orientation dispersion and density imagingMotor cortexAdultmedicine.medical_specialtymotor thresholdModels NeurologicalImmunologyNeuroimagingGrey matterWhite matterMultiple Sclerosis Relapsing-RemittingInternal medicineMotor systemFractional anisotropyexcitabilitymedicineNeuritesHumansbusiness.industryElectromyographyMultiple sclerosisRC581-607medicine.diseaseEvoked Potentials MotorTranscranial magnetic stimulationImmunologic diseases. AllergybusinessNeurosciencePsychomotor PerformanceDiffusion MRIFrontiers in Immunology
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Plant phenology and genetic variability in root and nodule development strongly influence genetic structuring of Rhizobium leguminosarum biovar vicia…

2008

Publication Inra prise en compte dans l'analyse bibliométrique des publications scientifiques mondiales sur les Fruits, les Légumes et la Pomme de terre. Période 2000-2012. http://prodinra.inra.fr/record/256699; International audience; The symbiotic relationships between legumes and their nitrogen (N-2)-fixing bacterial partners (rhizobia) vary in effectiveness to promote plant growth according to both bacterial and legume genotype. To assess the selective effect of host plant on its microsymbionts, the influence of the pea (Pisum sativum) genotype on the relative nodulation success of Rhizobium leguminosarum biovar viciae (Rlv) genotypes from the soil populations during plant development h…

SELECTION0106 biological sciencesGENETIC VARIABILITYGenotypePhysiologyPlant Science01 natural sciencesRHIZOBIUM LEGUMINOSARUM BIOVAR VICIAERhizobia03 medical and health sciencesSativumSymbiosisGenotypeBotanyDNA Ribosomal SpacerGenetic variabilitySymbiosisLegumePhylogenySoil Microbiology2. Zero hunger0303 health sciencesRhizosphereRhizobium leguminosarumbiology030306 microbiologyPeasfood and beveragesbiology.organism_classification[SDV.BV.PEP]Life Sciences [q-bio]/Vegetal Biology/Phytopathology and phytopharmacyGenetic structureMutationNODDRoot Nodules PlantSequence Alignment010606 plant biology & botanyThe New phytologistReferences
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