Search results for "NOGEL"
showing 10 items of 121 documents
Insights into localized manipulation of organogel-related microcrystalline spherulite formation
2015
Abstract The formation processes of microcrystalline spherulitic fiber systems related to bile acid amides were determined to include dominant interface-related aspects, the role of which were studied in terms of potential manipulation and increased control over the overall structure of the networks. The nucleation and growth properties and aggregation of two lithocholyl amide derivatives were studied in several organic solvents using thermomicroscopy, as well as thermal control at macroscopic level. Nucleation/crystallization at interfaces was observed to act as the main route for the formation of microcrystalline fibers/solids in six gelator–solvent systems, in which spherulite formation …
High Optical Performance of Cyan‐Emissive CsPbBr3 Perovskite Quantum Dots Embedded in Molecular Organogels
2021
This is the pre-peer reviewed version of the following article: High Optical Performance of Cyan‐Emissive CsPbBr3 Perovskite Quantum Dots Embedded in Molecular Organogels, which has been published in final form at https://doi.org/10.1002/adom.202001786. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions." Perovskite quantum dots (PQDs) have fascinating optoelectronic properties, such as high photoluminescence quantum yield (PLQY) for a broad range of materials, and the possibility to obtain different bandgaps with the same material or halide combinations. Nevertheless, blue‐emissive materials generally present…
Two-component self-assembly with solvent leading to "wet" and microcrystalline organogel fibers
2014
Abstract Hypothesis The microcrystalline fibers of N -(2-aminoethyl)-3α-hydroxy-5β-cholan-24-amide 1 provided a useful model system for studying the complex relationship between morphology, experimental parameters, solvent, and the phenomenon of organogelation. The presence of solvents in the solid forms of 1 along with crystallization behavior suggested solvate formation and polymorphic behavior. Experiments Forty solid state- and xerogel samples of 1 formed in organic solvents and in three categories of experimental conditions were analyzed with single crystal X-ray diffraction (XRD), powder X-ray diffraction (PXRD), Raman microscopy, and attenuated total reflection Fourier-transform infr…
Double-Network-Structured Graphene Oxide-Containing Nanogels as Photothermal Agents for the Treatment of Colorectal Cancer.
2017
Here, we reported the production of hyaluronic acid/polyaspartamide-based double-network nanogels for the potential treatment of colorectal carcinoma. Graphene oxide, thanks to the huge aromatic surface area, allows to easily load high amount of irinotecan (33.0% w/w) and confers to the system hyperthermic properties when irradiated with a near-infrared (NIR) laser beam. We demonstrate that the release of antitumor drug is influenced both by the pH of the external medium and the NIR irradiation process. In vitro biological studies, conducted on human colon cancer cells (HCT 116), revealed that nanogels are uptaken by the cancer cells and, in the presence of the antitumor drug, can produce a…
Organic salts and aromatic substrates in two-component gel phase formation: the study of properties and release processes
2015
To identify gel phases able to act as confined reaction media or materials for the removal of organic pollutants, we studied two-component gel phases formed by naphthalenedisulfonate diimidazolium salts in the presence of some organic guests, in 1-propanol solution. Guests differing in π-surface area, bulkiness and electronic properties were taken into account. Soft materials obtained were investigated for their thermal stability, self-repairing ability and morphology. Furthermore, two-component gel phase formation was studied using resonance light scattering (RLS) measurements. Guest release processes from the gel phase were also studied. These processes were monitored as a function of tim…
Radiation-Engineered Multi-Functional Nanogels As Nanoscale Building Blocks Of Useful Biomedical Devices
2011
Radiation-engineered multifunctional nanogels: a versatile platform with theranostic capabilities for cancer
2018
Under a rational desing, combining biologically active molecules, ligand to specific cell receptors and fluorescent, radioactive or paramagnetic labels into a single nano-object can bride the unique properties of the individual components and impruve conventional sensing, imaging and therapeutic efficaces.
Radiation Engineering of Multifunctional Nanogels
2016
Nanogels combine the favourable properties of hydrogels with those of colloids. They can be soft and conformable, stimuli-responsive and highly permeable, and can expose a large surface with functional groups for conjugation to small and large molecules, and even macromolecules. They are among the very few systems that can be generated and used as aqueous dispersions. Nanogels are emerging materials for targeted drug delivery and bio-imaging, but they have also shown potential for water purification and in catalysis. The possibility of manufacturing nanogels with a simple process and at relatively low cost is a key criterion for their continued development and successful application. This p…
Glutathione-sensitive nanogels for drug release
2014
Nanogels (NGs) synthesized by pulsed electron-beam irradiation of semi-dilute poly (N-vinyl pyrrolidone) (PVP) aqueous solutions, at relatively low energy per pulse and doses within the sterilization dose range, represent a very interesting family of polymeric nanocarriers. Ionizing irradiation-induced crosslinking of PVP allows to control particle size, and surface chemistry of the polymer nanoparticles without making use of catalysts, organic solvents or surfactants, and with beneficial effects onto the purity and hence biocompatibility of the final products obtained. Furthermore, the availability of reactive functional groups, either generated by the radiation or purposely grafted via co…