Search results for "NOTA"

showing 10 items of 592 documents

Surfing transcriptomic landscapes. A step beyond the annotation of chromosome 16 proteome

2013

All participating laboratories are members of ProteoRed-ISCIII.-- et al.

ProteomicsProteomeSequence analysisBioinformaticsBiologyMicrobiologíaENCODEProteomicsBiochemistryMass SpectrometryTranscriptome03 medical and health sciencesAnnotationChromosome 16RNA-Seq. ENCODEHuman proteome projectHumansHuman proteome projectTranscriptomics030304 developmental biologyGenetics0303 health sciencesSequence Analysis RNA030302 biochemistry & molecular biologyGeneral ChemistryChromosome 163. Good healthProteomeTranscriptomeChromosomes Human Pair 16Chromatography Liquid
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General Statistical Framework for Quantitative Proteomics by Stable Isotope Labeling

2014

Pedro J. Navarro et al.

ProteomicsSaccharomyces cerevisiae ProteinsProteomeQuantitative proteomicsGene Expressionstable isotope labelingSaccharomyces cerevisiaeyeastOxygen Isotopescomputer.software_genreBiochemistryStatistical powerInterpretation (model theory)statistical analysisStable isotope labeling by amino acids in cell cultureQuantitative proteomicsData MiningModels StatisticalChromatographyChemistryMolecular Sequence AnnotationHydrogen PeroxideGeneral ChemistryVariance (accounting)Isotope LabelingStable Isotope LabelingBiological systemNull hypothesiscomputerData integrationJournal of Proteome Research
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CiliaCarta: An integrated and validated compendium of ciliary genes

2019

The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wide range of genetic diseases collectively called ciliopathies. The current rate at which new ciliopathy genes are identified suggests that many ciliary components remain undiscovered. We generated and rigorously analyzed genomic, proteomic, transcriptomic and evolutionary data and systematically integrated these using Bayesian statistics into a predictive score for ciliary function. This resulted in 285 candidate ciliary genes. We generated independent experimental evidence of ciliary associations for 24 out of 36 analyzed candidate proteins using multiple cell and animal model systems (mouse…

ProteomicsSensory ReceptorsNematodaSocial SciencesCiliopathiesBiochemistrySensory disorders Donders Center for Medical Neuroscience [Radboudumc 12]Transcriptome0302 clinical medicineAnimal CellsPsychologyRETINAL PHOTORECEPTOR CELLSExomeNeurons0303 health sciences030302 biochemistry & molecular biologyEukaryotaGenomicsPRIMARY CILIUMthecilium3. Good healthNucleic acidsGenetic interferenceOsteichthyesMedicineEpigeneticsCellular Structures and OrganellesCellular Typesproteomic databasesSensory Receptor CellsScienceeducationCiliary genesLEBER CONGENITAL AMAUROSISGenomics03 medical and health sciencesGeneticsCiliaCaenorhabditis elegansIDENTIFICATIONMUTATIONSEmbryosciliaOrganismsBiology and Life SciencesBayes TheoremMolecular Sequence Annotationmedicine.diseaseInvertebratesFishciliary proteomeAnimal StudiesCaenorhabditisGene expressionembryos030217 neurology & neurosurgeryDevelopmental BiologyNeurosciencePhotoreceptorsCandidate geneEmbryologyOligonucleotidesMorpholinoDatabase and Informatics MethodsRNA interferenceBayesian classifierTRANSITION ZONEZebrafishAntisense OligonucleotidesZebrafishGeneticsMultidisciplinarySpectrometric Identification of ProteinsProteomic DatabasesNucleotidesCiliumQStable Isotope Labeling by Amino Acids in Cell CultureRphotoreceptorsMetabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6]Animal ModelsPhenotypeINTRAFLAGELLAR TRANSPORTDIFFERENTIATIONPhenotypeExperimental Organism SystemsCaenorhabditis ElegansVertebratesSensory PerceptionResearch ArticleSignal TransductionEXPRESSIONStable isotope labeling by amino acids in cell cultureComputational biologyBiologyResearch and Analysis MethodsSOLUTE-CARRIER-PROTEINModel OrganismsmedicineAnimalsdata integration030304 developmental biologyAfferent NeuronsReproducibility of ResultsCell Biologyzebrafishbiology.organism_classificationCiliopathyRenal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11]Biological DatabasesCellular NeuroscienceRNAOSCP1CiliaCartaPLoS ONE
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BAG3 Proteomic Signature under Proteostasis Stress

2020

The multifunctional HSP70 co-chaperone BAG3 (BCL-2-associated athanogene 3) represents a key player in the quality control of the cellular proteostasis network. In response to stress, BAG3 specifically targets aggregation-prone proteins to the perinuclear aggresome and promotes their degradation via BAG3-mediated selective macroautophagy. To adapt cellular homeostasis to stress, BAG3 modulates and functions in various cellular processes and signaling pathways. Noteworthy, dysfunction and deregulation of BAG3 and its pathway are pathophysiologically linked to myopathies, cancer, and neurodegenerative disorders. Here, we report a BAG3 proteomic signature under proteostasis stress. To elucidat…

ProteomicsautophagyCell signalingCellular homeostasisinteractomeBiologyBAG3InteractomeArticleStress PhysiologicalHumansddc:610Protein Interaction Mapsprotein quality controllcsh:QH301-705.5Adaptor Proteins Signal TransducingProto-Oncogene Proteins c-yesproteostasisBAG3AutophagyMolecular Sequence Annotationstress responseGeneral MedicineCell biologyGene OntologyHEK293 CellsAggresomeProteostasislcsh:Biology (General)Multivariate AnalysisSignal transductionApoptosis Regulatory ProteinsProteasome InhibitorsProtein BindingCells
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Pragmatica respectant a les Notes dels Actes rebuts per los Notaris difunts, y Regents de aquelles / manada publicar per lo ... Iusticia en les cause…

1681

Crida per a donar a coneixer la Pragmàtica, publicada el 22 d'Octubre de 1681 en la Ciutat de València Caplletra ornada al començament del text Sign. : A6 Reclams

Protocols notarials Comunitat Valenciana S.XVII Obres anteriors a 1800
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Ara ojats queus fan saber de part del Magnifich Pere de Caspe ... Iusticia en lo Civil de la present Ciutat de Valencia ... al qual ... pertany tenir…

1645

Sign.: []2

Protocols notarials València (Comunitat Valenciana) S.XVII Obres anteriors a 1800DIG-BH
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The Dawning of Computational Psychoanalysis

2014

In this paper, the author wishes first to highlight, within the general cultural context, some possible elementary computational psychoanalysis formalizations concerning Matte Blanco's bi-logic components through certain very elementary mathematical tools and notions drawn from theoretical physics and algebra. Afterwards, on the basis of recent work of Giampaolo Sasso (1999; 2005; 2011), relying on the crucial crossroad between neurosciences and psychoanalysis, it will be possible to identify some hints for further formalization attempts turned toward a computational psychoanalysis outlook. Lastly, possible interesting relationships with cognitive informatics are also outlined.

Psychoanalysisbi-logicComputer sciencemedia_common.quotation_subjectCultural contextdouble bindobject relationshipgroupoidoscillationsymmetry breakingObject RelationshipHuman-Computer InteractionresonanceconsciousneArtificial IntelligenceCognitive informaticsdenotational mathematics.introjective and projective processeAlgebra over a fieldConsciousnessbundleSoftwaremedia_commonInternational Journal of Cognitive Informatics and Natural Intelligence
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Impacto de las notas de prensa en las citas recibidas por los artículos publicados en Gaceta Sanitaria

2014

Antecedentes/Objetivos: Hay pocos estudios que analicen los factores que influyen sobre el factor de impacto bibliométrico de una revista y las notas de prensa son uno de estos factores. Se presenta un análisis del impacto en las citas recibidas por los artículos objeto de una nota de prensa elaborada desde Gaceta Sanitaria. Métodos: Se elaboró una base de datos con todos los artículos publicados en Gaceta Sanitaria entre 2007 y 2011. Para cada uno se registró el número de citas recibidas hasta el año 2012 (incluido) en la base de datos Web of Science. Para cada artículo se registró si había sido incluido o no en las notas de prensa elaboradas desde la revista. Desde 2007 hasta 2011 dos art…

PublicacionesMedicina Preventiva y Salud PúblicaNotas de prensaImpacto bibliométrico
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Common fixed points of mappings satisfying implicit relations in partial metric spaces

2013

Matthews, [S. G. Matthews, Partial metric topology, in: Proc. 8th Summer Conference on General Topology and Applications, in: Ann. New York Acad. Sci., vol. 728, 1994, pp. 183-197], introduced and studied the concept of partial metric space, as a part of the study of denotational semantics of dataflow networks. He also obtained a Banach type fixed point theorem on complete partial metric spaces. Very recently Berinde and Vetro, [V. Berinde, F. Vetro, Common fixed points of mappings satisfying implicit contractive conditions, Fixed Point Theory and Applications 2012, 2012:105], discussed, in the setting of metric and ordered metric spaces, coincidence point and common fixed point theorems fo…

Pure mathematicsAlgebra and Number TheoryDataflowCoincidence point common fixed point contraction implicit relation partial metric space.Fixed-point theoremFixed pointMetric spaceDenotational semanticsSettore MAT/05 - Analisi MatematicaCommon fixed pointGeneral topologyCoincidence pointAnalysisMathematicsJournal of Nonlinear Sciences and Applications
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Actions and Invariant Character Degrees

1993

point subgroup. In general, we use the same notation as in 6 and 7 .wx wxPart of the proof of Theorem A depends on the basic properties of theGajendragadkar p-special characters 1 and we assume the reader iswxfamiliar with those. However, we will repeatedly use a deeper fact: anirreducible character a of a Hall p-subgroup

Pure mathematicsAlgebra and Number TheoryInvariant (mathematics)NotationMathematicsJournal of Algebra
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