Search results for "NSC"
showing 10 items of 5810 documents
Genetic organization of the citCDEF locus and identification of mae and clyR genes from Leuconostoc mesenteroides.
1999
ABSTRACT In this paper, we describe two open reading frames coding for a NAD-dependent malic enzyme ( mae ) and a putative regulatory protein ( clyR ) found in the upstream region of citCDEFG of Leuconostoc mesenteroides subsp. cremoris 195. The transcriptional analysis of the citrate lyase locus revealed one polycistronic mRNA covering the mae and citCDEF genes. This transcript was detected only on RNA prepared from cells grown in the presence of citrate. Primer extension experiments suggest that clyR and the citrate lyase operon are expressed from a bidirectional A-T-rich promoter region located between mae and clyR.
Transcranial direct current stimulation preconditioning modulates the effect of high-frequency repetitive transcranial magnetic stimulation in the hu…
2012
Experimental studies emphasize the importance of homeostatic plasticity as a mean of stabilizing the properties of neural circuits. In the present work we combined two techniques able to produce short-term (5-Hz repetitive transcranial magnetic stimulation, rTMS) and long-term (transcranial direct current stimulation, tDCS) effects on corticospinal excitability to evaluate whether and how the effects of 5-Hz rTMS can be tuned by tDCS preconditioning. Twelve healthy subjects participated in the study. Brief trains of 5-Hz rTMS were applied to the primary motor cortex at an intensity of 120% of the resting motor threshold, with recording of the electromyograph traces evoked by each stimulus o…
Polyamines in Developing Stress-Resistant Crops
2012
F.Marco,R.Alcazar,T.Altabella,P.Carrasco,SarvajeetSinghGill,NarendraTuteja,andA.F. TiburcioPolyamines (PAs) are small protonated compounds with key roles in plant devel-opmentandphysiologicalprocesses.PAsmayalsofunctionasstressmessengersinplant responses to different stress signals. Recent studies using exogenous appli-cation of polyamines and more contemporary genetic manipulation of polyaminelevelsincropsandmodelspeciespointtotheirinvolvementinstressprotection.Thedifferentmechanismsbywhichpolyaminesexerttheirfunctionsarepresentlybeingunraveledandinvolvedifferentmodesofactionthataresummarizedinthischapter.Polyamines are integrated with other stress-related hormone pathways, such asabscisic…
Modelling temperature-dependent dynamics of single and mixed infections in a plant virus
2022
Multiple viral infection is an important issue in health and agriculture with strong impacts on society and the economy. Several investigations have dealt with the population dynamics of viruses with different dynamic properties, focusing on strain competition during multiple infections and the effects on viruses’ hosts. Recent interest has been on how multiple infections respond to abiotic factors such as temperature (T). This is especially important in the case of plant pathogens, whose dynamics could be affected significantly by global warming. However, few mathematical models incorporate the effect of T on parasite fitness, especially in mixed infections. Here, we investigate simple mat…
Integration of polyamins in the cold acclimation response
2011
8 páginas, 1 figura, 3 tablas -- PAGS nros. 31-38
Broadband Multi-wavelength Properties of M87 during the 2017 Event Horizon Telescope Campaign
2021
Full list of authors: EHT MWL Science Working Group; Algaba, J. C.; Anczarski, J.; Asada, K.; Baloković, M.; Chandra, S.; Cui, Y. -Z.; Falcone, A. D.; Giroletti, M.; Goddi, C.; Hada, K.; Haggard, D.; Jorstad, S.; Kaur, A.; Kawashima, T.; Keating, G.; Kim, J. -Y.; Kino, M.; Komossa, S.; Kravchenko, E. V.; Krichbaum, T. P.; Lee, S. -S.; Lu, R. -S.; Lucchini, M.; Markoff, S.; Neilsen, J.; Nowak, M. A.; Park, J.; Principe, G.; Ramakrishnan, V.; Reynolds, M. T.; Sasada, M.; Savchenko, S. S.; Williamson, K. E.; Event Horizon Telescope Collaboration; Akiyama, Kazunori; Alberdi, Antxon; Alef, Walter; Anantua, Richard; Azulay, Rebecca; Baczko, Anne-Kathrin; Ball, David; Barrett, John; Bintley, Dan; …
Achlya spiralis, a new aquatic oomycete with bent oogonial stalks, isolated from the Burgundian region of France
2008
Achlya spiralis sp. nov. was isolated from water samples collected in the river Tille in the Burgundian region of France. The new oomycete is described, illustrated and compared with related species of the genus Achlya. It is characterized by the presence of smooth-walled oogonia that are usually borne on bent or twisted oogonial stalks; mainly monoclinous, androgynous and diclinous antheridial branches and eccentric oospores which generally do not mature or mature after a long period of time. The internal transcribed spacer (ITS) region of its rRNA is comprised of 671 bases. The taxonomic description of this new species, its comparison with related oomycetes and the sequence of the ITS reg…
The 2020 magnetism roadmap
2020
Following the success and relevance of the 2014 and 2017 Magnetism Roadmap articles, this 2020 Magnetism Roadmap edition takes yet another timely look at newly relevant and highly active areas in magnetism research. The overall layout of this article is unchanged, given that it has proved the most appropriate way to convey the most relevant aspects of today's magnetism research in a wide variety of sub-fields to a broad readership. A different group of experts has again been selected for this article, representing both the breadth of new research areas, and the desire to incorporate different voices and viewpoints. The latter is especially relevant for thistype of article, in which one's fi…
Modulation of action tremor by repetitive transcranial magnetic stimulation in multiple sclerosis patients
2014
Background: Patients affected by Multiple Sclerosis (MS) can show a tremor of their upper limbs, mostly during the performing of finalised action (action tremor) or at the maintaining of a position against gravity (postural tremor), as key clinical feature of their disease. Objectives: In order to reduce the tremor, patients underwent to repetitive transcranial magnetic stimulation (rTMS) of the primary motor cortex of left hemisphere. Methods: Eight patients affected by a middle form of MS were enrolled into the study. A standard neurological examination was carried out and the individual degree of disability was established employing the Expanded Disability Status Score (EDSS). At EDSS pa…
Isoquercitrin and polyphosphate co-enhance mineralization of human osteoblast-like SaOS-2 cells via separate activation of two RUNX2 cofactors AFT6 a…
2014
Isoquercitrin, a dietary phytoestrogen, is a potential stimulator of bone mineralization used for prophylaxis of osteoporotic disorders. Here we studied the combined effects of isoquercitrin, a cell membrane permeable 3-O-glucoside of quercetin, and polyphosphate [polyP], a naturally occurring inorganic polymer inducing bone formation, on mineralization of human osteoblast-like SaOS-2 cells. Both compounds isoquercitrin and polyP induce at non-toxic concentrations the mineralization process of SaOS-2 cells. Co-incubation experiments revealed that isoquercitrin (at 0.1 and 0.3μM), if given simultaneously with polyP (as Ca(2+) salt; at 3, 10, 30 and 100μM) amplifies the mineralization-enhanci…