Search results for "Naphthalenes"
showing 10 items of 90 documents
l-Tyrosine β-naphthylamide is a potent competitive inhibitor of tyramine N-(hydroxycinnamoyl)transferase in vitro
2001
L-Tyrosine beta-naphthylamide, a synthetic substrate designed to measure tyrosine aminopeptidase activity, is a potent inhibitor of hydroxycinnamoyl-CoA:tyramine N-(hydroxycinnamoyl)transferase (THT) purified from elicited tobacco cell-suspension cultures. The inhibition is competitive, with the inhibitor binding reversibly to the tyramine binding site of the enzyme. Similar results were obtained with THT extracted from elicited potato cell-suspension cultures. Ki values were found to be 0.66 microM for the enzyme from tobacco and 0.3 microM for the enzyme from potato. L-Tyrosine 7-amido-4-methylcoumarin, a fluorogenic substrate for tyrosine aminopeptidases, the structure of which is close …
CCDC 749023: Experimental Crystal Structure Determination
2010
Related Article: D.Siebler, C.Forster, K.Heinze|2010|Eur.J.Inorg.Chem.||523|doi:10.1002/ejic.200901051
CCDC 749024: Experimental Crystal Structure Determination
2010
Related Article: D.Siebler, C.Forster, K.Heinze|2010|Eur.J.Inorg.Chem.||523|doi:10.1002/ejic.200901051
CCDC 168013: Experimental Crystal Structure Determination
2002
Related Article: L.Gutierrez, G.Alzuet, J.A.Real, J.Cano, J.Borras, A.Castineiras|2002|Eur.J.Inorg.Chem.||2094|doi:10.1002/1099-0682(200208)2002:8<2094::AID-EJIC2094>3.0.CO;2-Z
CCDC 150110: Experimental Crystal Structure Determination
2001
Related Article: L.Gutierrez, G.Alzuet, J.Borras, M.Liu-Gonzalez, F.Sanz, A.Castineiras|2001|Polyhedron|20|703|doi:10.1016/S0277-5387(01)00717-3
CCDC 194205: Experimental Crystal Structure Determination
2003
Related Article: M.Gonzalez-Alvarez, G.Alzuet, J.Borras, B.Macias, J.M.Montejo-Bernardo, S.Garcia-Granda|2003|Z.Anorg.Allg.Chem.|629|239|doi:10.1002/zaac.200390038
CCDC 663387: Experimental Crystal Structure Determination
2009
Related Article: J.L.Garcia-Gimenez, G.Alzuet, M.Gonzalez-Alvarez, M.Liu-Gonzalez, A.Castineiras, J.Borras|2009|J.Inorg.Biochem.|103|243|doi:10.1016/j.jinorgbio.2008.10.015
Oxidative nuclease activity of ferromagnetically coupled μ-hydroxo-μ-propionato copper(II) complexes [Cu3(L)2(μ-OH)2(μ-propionato)2] (L=N-(pyrid-2-yl…
2008
Three doubly-bridged, trinuclear copper(II) compounds with hydroxo and carboxylato bridges, ∞ 1 [Cu 3 (L1) 2 (μ-OH) 2 (μ-propionato) 2 ] ∞ 1 [ Cu 3 ( L 1 ) 2 ( μ - OH ) 2 ( μ - propionato ) 2 ] (1) , [Cu 3 (L2) 2 (μ-OH) 2 (μ-propionato) 2 (DMF) 2 ] (2) and ∞ 1 {[Cu 3 (L3) 2 (μ-OH) 2 (μ-propionato) 2 ]} ∞ 1 { [ Cu 3 ( L 3 ) 2 ( μ - OH ) 2 ( μ - propionato ) 2 ] } [Cu 3 (L3) 2 (μ-OH) 2 (μ-propionato) 2 (DMF) 2 ]} (3) [HL1 = N -(pyrid-2-ylmethyl)benzenesulfonylamide, HL2 = N -(pyrid-2-ylmethyl)toluenesulfonylamide, HL3 = N -(pyrid-2-ylmethyl)naphthalenesulfonylamide], have been synthesized and characterized. 1 is built from [Cu 3 (L1) 2 (μ-OH) 2 (μ-propionato) 2 ] clusters. Each unit contai…
Molecular recognition of naphthalene diimide ligands by telomeric quadruplex-DNA: the importance of the protonation state and mediated hydrogen bonds.
2016
In depth Monte Carlo conformational scans in combination with molecular dynamics (MD) simulations and electronic structure calculations were applied in order to study the molecular recognition process between tetrasubstituted naphthalene diimide (ND) guests and G-quadruplex (G4) DNA receptors. ND guests are a promising class of telomere stabilizers due to which they are used in novel anticancer therapeutics. Though several ND guests have been studied experimentally in the past, the protonation state under physiological conditions is still unclear. Based on chemical intuition, in the case of N-methyl-piperazine substitution, different protonation states are possible and might play a crucial …
Naphthalene Derivatives from the Roots of Pentas parvifolia and Pentas bussei
2016
The phytochemical investigation of the CH2Cl2/MeOH (1:1) extract of the roots of Pentas parvifolia led to the isolation of three new naphthalenes, parvinaphthols A (1), B (2), and C (3), two known anthraquinones, and five known naphthalene derivatives. Similar investigation of the roots of Pentas bussei afforded a new polycyclic naphthalene, busseihydroquinone E (4), a new 2,2'-binaphthralenyl-1,1'-dione, busseihydroquinone F (5), and five known naphthalenes. All purified metabolites were characterized by NMR and MS data analyses, whereas the absolute configurations of 3 and 4 were determined by single-crystal X-ray diffraction studies. The E-geometry of compound 5 was supported by DFT-base…