Search results for "Neck"

showing 10 items of 745 documents

Uncommon clinical presentation of Kimura’s disease as bilateral retroauricular masses in a young Malian male: successful surgical approach.

2016

We present a case of a 27 year-old Malian male referred to our hospital for two large, painless retroauricolar masses that had appeared two years earlier. Bilateral cervical painless lymphadenopathy was present at physical examination, without any other systemic symptoms. His history was relevant for bilateral Kimura’s disease lesions resected 5 years earlier in the same locations. Lymphocytosis and a mild hypereosinophilia were found in routine blood tests, together with increased total IgE levels. After surgery, histology showed lymphoid infiltrates with reactive prominent germinal centres containing eosinophils, suggesting relapse of Kimura’s disease, in the context of nonencapsulated fi…

AdultMaleKimura diseaseCancer ResearchPhysiologyEndocrinology Diabetes and MetabolismImmunologyAngiolymphoid Hyperplasia with EosinophiliaNon-AsianFibrosisKeloid Kimura disease neck retroauricolar non-AsianTreatment OutcomeEndocrinologyOncologyRecurrenceKeloidPhysiology (medical)retroauricolarHumansImmunology and AllergyRetroauricularNeck
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High constant incidence rates of second primary cancers of the head and neck: a pooled analysis of 13 cancer registries

2010

Scanty data are available on the incidence (i.e., the absolute risk) of second cancers of the head and neck (HN) and its pattern with age. We investigated this issue using data from a multicentric study of 13 population-based cancer registries from Europe, Canada, Australia and Singapore for the years 1943-2000. A total of 99,257 patients had a first primary HN cancer (15,985 tongue, 22,378 mouth, 20,758 pharyngeal, and 40,190 laryngeal cancer), contributing to 489,855 person-years of follow-up. 1294 of the patients (1.3%) were diagnosed with second HN cancers (342 tongue, 345 mouth, 418 pharynx, and 189 larynx). Male incidence rates of first HN cancer steeply increased from 0.68/100,000 at…

AdultMaleLarynxOncologyCancer Researchmedicine.medical_specialtyPopulationArticlehead and neckTongueInternal medicineEpidemiologymedicineHumanscancerpooled analysiRegistrieseducationAgedAged 80 and overGynecologyeducation.field_of_studybusiness.industryIncidence (epidemiology)second neoplasmsHead and neck cancerPharynxCancerNeoplasms Second PrimaryMiddle Agedmedicine.diseasesecond primaryAdult ; Aged ; Aged 80 and over ; Female ; Head and Neck Neoplasms/epidemiology* ; Humans ; Incidence ; Male ; Middle Aged ; Neoplasms Second Primary/epidemiology*; Registriesmedicine.anatomical_structureOncologyageHead and Neck Neoplasmscancer registriesincidenceFemalehead and neck cancerHigh constant incidence ratebusiness
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Rupture of supra-aortic neck arteries due to lesions caused by tracheal tubes

1984

Haemorrhages from the common carotid or innominate artery caused by tracheal tubes are rare but dramatic complications of head and neck surgery. Patients with metal tracheostomy cannulas or patients in the phase of wound healing after radical tumour resections of the pharynx and larynx run a greater risk. Following extensive tumour resections and radiation of the upper respiratory and digestive tracts in 680 patients, acute bleeding of the larger neck arteries occurred in 18 patients. In four of these cases, fistulae developed in the innominate or common carotid artery. These ruptures were caused by both plastic and metal tracheal tubes.

AdultMaleLarynxmedicine.medical_specialtyHemorrhagePostoperative Complicationsmedicine.arteryIntubation IntratrachealmedicineHumansCommon carotid arteryRespiratory systemLaryngeal NeoplasmsBrachiocephalic TrunkAgedRupturebusiness.industryPharynxGeneral MedicineMiddle AgedSurgerymedicine.anatomical_structureOtorhinolaryngologyHead and neck surgeryDigestive tractCarotid Artery InjuriesbusinessAortic neckArteryThe Journal of Laryngology & Otology
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Quality of life during the first year after partial laryngectomy: Longitudinal study

2018

This prospective study was conducted to assess changes in quality of life (QOL) of patients who undergo a partial laryngectomy.The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaires Core and Head and Neck (EORTC-QLQ-C30, QLQ-HN35) were used preprocedure (n = 218), 1 week (n = 159), 3 months (n = 122), and 1 year after partial laryngectomy (n = 88). Changes over time were analyzed with the Wilcoxon signed rank test and the Holm-Bonferroni method, and interpreted regarding clinical relevance.Most subscales worsened 1 week postprocedure, but many recovered to baseline level after 1 year. Dyspnea and cognitive functioning deteriorated over time, with worst…

AdultMaleLongitudinal studymedicine.medical_specialtyTime FactorsLaryngectomy03 medical and health sciencesPostoperative Complications0302 clinical medicineQuality of lifeSurveys and QuestionnairesHumansMedicineLongitudinal StudiesProspective Studies030223 otorhinolaryngologyProspective cohort studyHead and neckLaryngeal NeoplasmsPartial laryngectomyAgedAged 80 and overbusiness.industryCarcinomaHead and neck cancersocial sciencesMiddle Agedmedicine.diseasehumanitiesOtorhinolaryngology030220 oncology & carcinogenesisQuality of LifePhysical therapyFemalebusinessHead & Neck
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Endocrine response after cervical manipulation and mobilization in people with chronic mechanical neck pain: a randomized controlled trial

2019

BACKGROUND: Most of the research on the effects of spinal manipulation on endocrine function has been done on healthy subjects and has yielded contradictory results. The potential role of cervical manual therapy intervention in order to induce changes in the endocrine system has not yet been investigated. AIM: The aim of this trial is to compare the effects on salivary cortisol levels and clinical outcomes of cervical manipulation versus cervical mobilization or sham manipulation in patients with chronic mechanical neck pain. DESIGN: Randomized controlled trial. SETTING: University of Alcala de Henares: outpatient (referrals from office workers). POPULATION: A total of 83 patients with chro…

AdultMaleManipulation SpinalPain Threshold030506 rehabilitationHydrocortisonePopulationPhysical Therapy Sports Therapy and RehabilitationSpinal manipulationlaw.inventionDisability Evaluation03 medical and health sciences0302 clinical medicineRandomized controlled triallawThreshold of painHumansMedicineRange of Motion ArticularSalivaeducationPain MeasurementHydrocortisoneeducation.field_of_studyNeck painNeck Painbusiness.industryRehabilitationMiddle AgedAnesthesiaFemaleChronic PainManual therapymedicine.symptom0305 other medical sciencebusinessRange of motion030217 neurology & neurosurgerymedicine.drugEuropean Journal of Physical and Rehabilitation Medicine
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Immediate effects of active cranio-cervical flexion exercise versus passive mobilisation of the upper cervical spine on pain and performance on the c…

2014

This study compared the immediate effects of an assisted plus active cranio-cervical flexion exercise (exercise group) versus a passive mobilisation plus assisted cranio-cervical flexion (mobilisation group) on performance of the cranio-cervical flexion test (CCFT), cervical range of motion (ROM) and pain in patients with chronic neck pain. Eighteen volunteers with chronic idiopathic neck pain participated in the study and were randomised to one of the two intervention groups. Current level of pain, cervical ROM and pain perceived during movement, pressure pain threshold (PPT) and surface electromyography (EMG) during performance of the CCFT were measured before and immediately after the in…

AdultMaleManipulation Spinalmedicine.medical_specialtyAnterior scaleneFlexion TestPhysical Therapy Sports Therapy and RehabilitationElectromyographyRisk AssessmentSeverity of Illness Index03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationmedicineHumansIn patientSingle-Blind MethodRange of Motion ArticularPain Measurement030222 orthopedicsNeck painAnalysis of VarianceNeck Painmedicine.diagnostic_testbusiness.industryElectromyographyMotor controlGeneral MedicineMiddle AgedCervical spineExercise Therapybody regionsAtlanto-Occipital JointTreatment OutcomeChronic DiseasePhysical therapyFemaleActive treatmentmedicine.symptombusiness030217 neurology & neurosurgeryFollow-Up StudiesManual therapy
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A Phase II Study of Levofolinic Acid and 5-Fluorouracil Plus Cisplatin in Patients with Advanced Head and Neck Squamous Cell Carcinoma

1993

Forty patients with advanced squamous cell carcinoma of the head and neck (SCHNC) were treated with a combination of levofolinic acid 100 mg/m2+5-fluorouracil 375 mg/m2 in a 4-hour infusion plus cisplatin 20 mg/m2 in a 2-hour infusion for 5 consecutive days, repeated every 21-28 days. In the group of 20 previously untreated patients, a 90% overall response rate (ORR) with a 30% complete response rate (CRR) was obtained. In the group of 20 pretreated patients with recurrent and/or metastatic SCHNC, a 55% ORR with 15% CRR was achieved. This treatment was given on an outpatient basis and was generally very well tolerated with only 2 patients requiring hospitalization. Grade 1-2 gastrointestina…

AdultMaleOncologyCancer Researchmedicine.medical_specialtyPathologymedicine.medical_treatmentLeucovorinPhases of clinical researchInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansIn patientHead and neckAgedNeoplasm StagingCisplatinChemotherapybusiness.industryStereoisomerismGeneral MedicineMiddle Agedmedicine.diseaseCombined Modality TherapyHead and neck squamous-cell carcinomaOncologyHead and Neck NeoplasmsFluorouracilCarcinoma Squamous CellFemaleFluorouracilCisplatinbusinessLevofolinic acidmedicine.drugOncology
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Overexpression of GLUT-1 is associated with resistance to radiotherapy and adverse prognosis in squamous cell carcinoma of the oral cavity

2006

This study tested the hypothesis that GLUT-1 is a marker of radioresistance in oral squamous cell carcinomas (OSCC). A GLUT-1 labeling index (LI) was determined by immunohistochemistry in 40 pretreatment OSCC biopsies. Radiation responses were categorized by histopathology of the resection specimens. Associations between the LI and radiation response, Kaplan-Meier survival estimates and Cox regression analysis for the variables GLUT-1, T-stage, N-stage and chemotherapy were examined. The median LI was 64.2% (range 14-100%). Tumors with65% of GLUT-1+cells were more resistant to radiation (p=0.023). Overall survival was higher (p=0.044) for subjects with low LI (median value) than those with …

AdultMaleOncologyendocrine systemCancer Researchmedicine.medical_specialtyPathologymedicine.medical_treatmentAntineoplastic AgentsRadiation ToleranceImmunoenzyme TechniquesRadioresistanceInternal medicineBiomarkers TumorHumansMedicineAgedRetrospective StudiesGlucose Transporter Type 1Chemotherapybusiness.industryProportional hazards modelHead and neck cancerMiddle AgedPrognosismedicine.diseaseCombined Modality TherapySurvival AnalysisNeoplasm ProteinsRadiation therapystomatognathic diseasesTreatment OutcomeOncologyEpidermoid carcinomaCarcinoma Squamous CellImmunohistochemistryFemaleMouth NeoplasmsHistopathologyOral Surgerybusinesshormones hormone substitutes and hormone antagonistsOral Oncology
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Cachexia induces head and neck changes in locally advanced oropharyngeal carcinoma during definitive cisplatin and image-guided volumetric-modulated …

2015

Cancer cachexia is a syndrome characterized by weight loss (WL) and sarcopenia. Aim of the study was to assess the impact of cachexia on head and neck changes during definitive cisplatin and image-guided volumetric-modulated arc radiation therapy in a series of locally advanced oropharyngeal cancer.Volume variations of sternocleidomastoid muscle (SCM) were considered as surrogate of muscle changes related to sarcopenia. Two head and neck diameters, encompassing the cranial limits of II and III nodal levels (defined as 'head diameter' and 'neck diameter', respectively), were measured. All parameters were defined retrospectively by means of on-board cone beam computed tomography images at 1-8…

AdultMaleOncologymedicine.medical_specialtyCachexiamedicine.medical_treatmentLocally advancedMedicine (miscellaneous)030218 nuclear medicine & medical imagingCachexia03 medical and health sciences0302 clinical medicineInternal medicineWeight LossCarcinomamedicineHumansskin and connective tissue diseasesAgedCisplatinNutrition and DieteticsArc (protein)business.industryMiddle Agedmedicine.diseaseRadiation therapyOropharyngeal NeoplasmsOropharyngeal Carcinoma030220 oncology & carcinogenesisSarcopeniaFemaleRadiotherapy Intensity-Modulatedsense organsRadiologyCisplatinbusinessHeadNeckmedicine.drugEuropean Journal of Clinical Nutrition
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DNA measurements for monitoring chemotherapy in advanced head and neck carcinomas

1994

Background. Quantitative DNA measurements have demonstrated prognostic relevance in various malignancies, including head and neck cancer. The application of DNA measurements in monitoring and predicting the outcome of chemotherapy in treating patients with head and neck cancer was investigated. Methods. Twenty-five patients with advanced squamous cell carcinomas of the head and neck who underwent primary chemotherapy with three courses of cisplatin and 5-fluorouracil (5-FU) were examined in this study. Cytologic smears from the tumor site, as well as from normal mucosa, were taken before and 1 week after each course of chemotherapy. Quantitative DNA measurements were performed using an auto…

AdultMaleOncologymedicine.medical_specialtyPathologymedicine.medical_treatmentCellchemistry.chemical_compoundText miningCytologyInternal medicinemedicineHumansAgedCisplatinChemotherapybusiness.industryRemission InductionHead and neck cancerHistologyDNA NeoplasmMiddle AgedPrognosismedicine.diseaseTreatment Outcomemedicine.anatomical_structureOtorhinolaryngologychemistryHead and Neck NeoplasmsCarcinoma Squamous CellFemaleDrug MonitoringbusinessDNAmedicine.drugHead & Neck
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