Search results for "Neet"

showing 10 items of 1432 documents

Discovery of varlaxins, new aeruginosin-type inhibitors of human trypsins

2022

Low-molecular weight natural products display vast structural diversity and have played a key role in the development of novel therapeutics. Here we report the discovery of novel members of the aeruginosin family of natural products, which we named varlaxins. The chemical structures of varlaxins 1046A and 1022A were determined using a combination of mass spectrometry, analysis of one- and two-dimensional NMR spectra, and HPLC analysis of Marfey's derivatives. These analyses revealed that varlaxins 1046A and 1022A are composed of the following moieties: 2-O-methylglyceric acid 3-O-sulfate, isoleucine, 2-carboxy-6-hydroxyoctahydroindole (Choi), and a terminal arginine derivative. Varlaxins 10…

EXPRESSIONentsyymitBIOSYNTHETIC GENE-CLUSTERArginineBiochemistryMICROCYSTIS298-AHumansTrypsinPhysical and Theoretical ChemistrysyanobakteeritChromatography High Pressure LiquidtrypsiinitinhibiittoritNOSTOC SPBiological ProductsMolecular StructureIDENTIFICATIONOrganic ChemistryPEPTIDESseriiniproteaasiluonnonaineetEVOLUTIONPRSS3/MESOTRYPSINbiotekniikka1182 Biochemistry cell and molecular biologyhuman activitiesRESISTANCE
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Decreased intersubject synchrony in dynamic valence ratings of sad movie contents in dysphoric individuals

2021

Emotional reactions to movies are typically similar between people. However, depressive symptoms decrease synchrony in brain responses. Less is known about the effect of depressive symptoms on intersubject synchrony in conscious stimulus-related processing. In this study, we presented amusing, sad and fearful movie clips to dysphoric individuals (those with elevated depressive symptoms) and control participants to dynamically rate the clips’ valences (positive vs. negative). We analysed both the valence ratings’ mean values and intersubject correlation (ISC). We used electrodermal activity (EDA) to complement the measurement in a separate session. There were no group differences in either t…

EXPRESSIONmasennusAdultMale515 PsychologyScienceEmotionsMotion PicturesBRAIN ACTIVITYelokuvatArticleMECHANISMSYoung Adulttoiminnallinen magneettikuvaustunteetHuman behaviourHumanskognitiivinen psykologiatarkkaavaisuusMETAANALYSISDepressionsuruQATTENTIONRBrainBIASES113 Computer and information sciencesFacial Expressionvalenssi (psykologia)negatiivisuusPATTERNSMedicineRESPONSESScientific Reports
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Poor nutritional quality of primary producers and zooplankton driven by eutrophication is mitigated at upper trophic levels

2022

Eutrophication and rising water temperature in freshwaters may increase the total production of a lake while simultaneously reducing the nutritional quality of food web components. We evaluated how cyanobacteria blooms, driven by agricultural eutrophication (in eutrophic Lake Köyliöjärvi) or global warming (in mesotrophic Lake Pyhäjärvi), influence the biomass and structure of phytoplankton, zooplankton, and fish communities. In terms of the nutritional value of food web components, we evaluated changes in the ω-3 and ω-6 polyunsaturated fatty acids (PUFA) of phytoplankton and consumers at different trophic levels. Meanwhile, the lakes did not differ in their biomasses of phytoplankton, zoo…

Ecologyrehevöityminenplanktonontogenetic diet shiftrasvahapotvesiekosysteemitfreshwater food webselkärangattomatperchbenthic invertebratesphytoplanktonahvenmakea vesiravintoaineetbiomassa (ekologia)syanobakteeritravintoketjutEcology Evolution Behavior and Systematicspolyunsaturated fatty acidsNature and Landscape ConservationEcology and Evolution
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Outsourcing within the Nordic context: Care services for older people in Finland.

2018

The early 1990s economic setback brought significant reforms favoring the outsourcing of care in Finnish municipalities. Here, outsourcing refers to the practice of municipalities employing private organizations through different means (e.g., open tendering) to deliver public care services. In this context, this study examines the growth in the outsourcing of service housing and home-help services in 311 municipalities from 2001 to 2015 and investigates the municipal factors associated with outsourcing using four dimensions: care needs, population size, economic situation, and political ideology of the municipality. The findings reveal a steep increase in the outsourcing of home-help and se…

Economic growthFinancing GovernmentmunicipalityulkoistaminenContext (language use)hoivapalvelutvanhustenhuoltoOutsourcingolder people0502 economics and business050602 political science & public administrationHumans050207 economicsLife-span and Life-course StudiesFinlandDemographyAgedbusiness.industry05 social sciencesta5142Outsourced Servicessocial careHome Care Services0506 political scienceSetbackoutsourcingvanhuspalvelutSocial carePrivate SectorBusinessOlder peopleGerontologyjulkiset palvelutikääntyneetJournal of agingsocial policy
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Care poverty : unmet care needs in a Nordic welfare state

2019

This article introduces the concept of care poverty, defined as inadequate coverage of care needs resulting from an interplay between individual and societal factors, and examines its level and predictors among the 75+ population in Finland. The data come from a survey conducted in 2010 and 2015. Despite the universalistic goals of the Finnish care system, 26 percent of respondents with limitations in daily activities faced care poverty with regard to instrumental activities of daily living; the activities of daily living care poverty rate was 17 percent. Concerning instrumental activities of daily living, care poverty was associated with income level, health status and living arrangements,…

Economic growthHealth (social science)Sociology and Political SciencePovertyHealth PolicyPublic Health Environmental and Occupational Healthvanhuksetunmet needscare for older peopleWelfare statehoivapalvelutolder peoplehoivaresurssithoivaköyhyysvanhuspalvelutavuntarvecare povertyPsychologyFinlandikääntyneethoiva
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Digital ageing in Europe: a comparative analysis of Italian, Finnish and Swedish national policies on eHealth

2023

AbstractAgeing Europeans are today healthier than previous generations and often manage to live independently up to a high age. The proportion of people 80 years of age and older has increased significantly, and with high age the risk of multi-illness and dementia increases. Strong urbanisation processes have changed the demographic structure in rural areas, and young women and men have migrated towards the urban areas to study and work, while older persons have remained behind. This demographic challenge of increasing numbers of persons older than 80 years with care needs living in remote rural areas has become a major European social problem. In tackling this dilemma, many European countr…

Economic growthterveyspalvelutHealth (social science)hyvinvointiteknologiaSocial PsychologySettore SPS/08 - SOCIOLOGIA DEI PROCESSI CULTURALI E COMUNICATIVIhyvinvointipolitiikkahoivapalvelut03 medical and health sciences0302 clinical medicineArts and Humanities (miscellaneous)vertaileva tutkimusPolitical scienceeHealthGerontologi medicinsk/hälsovetenskaplig inriktningGerontology specialising in Medical and Health Sciencesdigitalisation030212 general & internal medicineSociologi (exklusive socialt arbete socialpsykologi och socialantropologi)teleterveydenhuoltodigitalisaatiodigital landscape of careharvaan asutut alueet030503 health policy & servicesSociology (excluding Social Work Social Psychology and Social Anthropology)Public Health Environmental and Occupational Healthqualitative comparisonikääntyminenageing policieseHealthvanhuspolitiikkaGeriatrics and Gerontology0305 other medical scienceikääntyneetAgeing and Society
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Technological and organizational capital : Where complementarities exist

2018

This study analyzes the complementarities between technological and organizational capital within enterprises. Different components of technological and organizational capital exert distinct—and often opposed—forces on each other. Our empirical results show that greater employee voice promotes firm productivity when combined with information technology, but harms firm productivity when combined with communication technology. On the other hand, flexible work design is positively associated with communication technology and negatively associated with information technology. peerReviewed

Economics and Econometricsaineeton pääomaStrategy and Managementtieto- ja viestintätekniikkatuottavuusinformation and communication technologiesOrganizational performanceNegatively associatedorganizational performanceManagement of Technology and Innovation0502 economics and business050207 economicsIndustrial organizationcomplementarityComputingMilieux_THECOMPUTINGPROFESSIONbusiness.industry05 social sciencesInformation technologyJob designGeneral MedicineorganizationGeneral Business Management and AccountingComplementarity (physics)yrityksetOrganizational capitalInformation and Communications Technologyfirm productivityEmployee voiceBusiness050203 business & management
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Young people not in employment, education or training (NEET): the role of basic competencies

2021

A top priority for public policies at both national and European levels, young people who are not in employment, education or training (NEET) face a risk of exclusion that varies in intensity from country to country. While education level plays a central role in these situations, viewing them through the lens of basic competencies sharpens the focus. After all, the international data show that the same level of qualification does not guarantee the same level of competencies everywhere. How can these differences be explained? To what extent do these basic competencies protect young people from becoming not in employment, education or training regardless of their level of qualification?

Education System Stratification[SHS.EDU] Humanities and Social Sciences/EducationNEETBasic Competencies
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Synthetic electromagnetic knot in a three-dimensional skyrmion

2018

We experimentally simulate a quantum-mechanical particle interacting with knotted electromagnetic fields.

Electromagnetic fieldField (physics)skyrmionsQuantum Hall effect01 natural sciences010305 fluids & plasmasElectromagnetism0103 physical sciencesQuantum systemClassical electromagnetismknotted electromagnetic field structureskvanttifysiikka010306 general physicsQuantumResearch ArticlesSpin-½PhysicsMultidisciplinaryta114Physicssähkömagneettiset kentätBose-Einstein condensatesSciAdv r-articlesCondensed Matter PhysicsMathematics::Geometric TopologyClassical mechanicsResearch ArticleScience Advances
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Health endowment and later-life outcomes in the labour market : Evidence using genetic risk scores and reduced-form models

2019

This paper examines the relationship between health endowment and later-life outcomes in the labour market. The analysis is based on reduced-form models in which labour market outcomes are regressed on genetic variants related to the increased risk of cardiovascular diseases. We use linked Finnish data that have many strengths. Genetic risk scores constitute exogenous measures for health endowment, and accurate administrative tax records on earnings, employment and social income transfers provide a comprehensive account of an individual’s long-term performance in the labour market. The results show that although the direction of an effect is generally consistent with theoretical reasoning, …

EmploymentgenetiikkaKansanterveystiede ympäristö ja työterveys - Public health care science environmental and occupational healthtyömarkkinatArticlehealth endowmentReduced-form regressionGeneticssocial income transferslcsh:Social sciences (General)ansiotasoreduced-form regressionperinnöllisyystiedelcsh:Public aspects of medicineterveydentilatyöllistyminentyöllisyyslcsh:RA1-1270Health endowmentOikeuslääketiede ja muut lääketieteet - Forensic science and other medical sciencesEarningsSocial income transferslcsh:H1-99geneettiset tekijätterveysearnings
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