Search results for "Neon"

showing 10 items of 760 documents

La cattedrale di Palermo tra Quattro e Cinquecento e le chiese neonormanne nella prima età moderna in Sicilia

2012

A partire dalla fine del Quattrocento e per buona parte del secolo successivo si costruirono in Sicilia una serie di chiese, con dimensioni più modeste delle cattedrali normanne, ma ispirate, soprattutto nella conformazione del santuario, al loro modello. A partire dall'esempio offerto dalla cattedrale di Palermo, i casi sinora emersi e le ragioni che possono avere provocato questo rinnovato successo sono argomento di questo saggio.

architettura religiosa Sicilia XV-XVI secolo neonormannoSettore ICAR/18 - Storia Dell'Architettura
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Molecular Basis for Endocrine Disruption by Pesticides Targeting Aromatase and Estrogen Receptor

2020

The intensive use of pesticides has led to their increasing presence in water, soil, and agricultural products. Mounting evidence indicates that some pesticides may be endocrine disrupting chemicals (EDCs), being therefore harmful for the human health and the environment. In this study, three pesticides, glyphosate, thiacloprid, and imidacloprid, were tested for their ability to interfere with estrogen biosynthesis and/or signaling, to evaluate their potential action as EDCs. Among the tested compounds, only glyphosate inhibited aromatase activity (up to 30%) via a non-competitive inhibition or a mixed inhibition mechanism depending on the concentration applied. Then, the ability of the thr…

aromatasemedicine.drug_classHealth Toxicology and Mutagenesislcsh:MedicineEstrogen receptorMixed inhibitionEndocrine Disruptors010501 environmental sciencesPharmacology01 natural sciencesArticle03 medical and health scienceschemistry.chemical_compoundImidaclopridReceptorsmedicineHumansAromataseestrogenic activity030304 developmental biology0105 earth and related environmental sciences0303 health sciencesAromatase inhibitorendocrine disrupting chemicalbiologyAromatase Inhibitorslcsh:RPublic Health Environmental and Occupational HealthEstrogenspesticidesPesticideThiaclopridEstrogenmolecular dynamicsReceptors EstrogenchemistryEstrogenMELN allosteric inhibitionbiology.proteingene reporter assayAromatase; Endocrine disrupting chemical; Estrogen receptor; Estrogenic activity; Gene reporter assay; MELN allosteric inhibition; Molecular dynamics; Neonicotinoids; Pesticides; Aromatase; Aromatase Inhibitors; Estrogens; Humans; Receptors Estrogen; Endocrine Disruptors; Pesticidesneonicotinoidsestrogen receptorInternational Journal of Environmental Research and Public Health
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Un caso di due gemelle monocoriali con una differente doppia atresia intestinale

2008

atresia intestinale neonato occlusione intestinaleSettore MED/20 - Chirurgia Pediatrica E Infantile
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Grave ipotonia neonatale con artrogriposi: descrizione di un caso clinico e problematiche diagnostiche

2014

atrogriposi ipotonia neonatale
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Segmentation et métrologie des sinus de Valsalva à partir de ciné-IRM

2012

Automatic segmentation of Valsalva sinuses from cine-MRI

body regionscongenital hereditary and neonatal diseases and abnormalities[ INFO.INFO-IM ] Computer Science [cs]/Medical Imaging[INFO.INFO-IM] Computer Science [cs]/Medical Imagingcardiovascular system[INFO.INFO-IM]Computer Science [cs]/Medical Imagingcardiovascular diseasescirculatory and respiratory physiology
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No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Data…

2021

Background. Lynch syndrome is the most common genetic predisposition for hereditary cancer. Carriers of pathogenic changes in mismatch repair (MMR) genes have an increased risk of developing colorectal (CRC), endometrial, ovarian, urinary tract, prostate, and other cancers, depending on which gene is malfunctioning. In Lynch syndrome, differences in cancer incidence (penetrance) according to the gene involved have led to the stratification of cancer surveillance. By contrast, any differences in penetrance determined by the type of pathogenic variant remain unknown. Objective. To determine cumulative incidences of cancer in carriers of truncating and missense or aberrant splicing pathogenic …

cancer incidence0302 clinical medicineMalalties hereditàriesMissense mutation8Q23.3CàncerCancerGenetics0303 health sciencesmedicine.diagnostic_testFactors de risc en les malaltiesMISMATCH REPAIR GENESRMLH1General MedicinePenetranceLynch syndrome3. Good healthsyöpägeenit030220 oncology & carcinogenesisMedicinesyöpätauditilmaantuvuusGenetic diseasescongenital hereditary and neonatal diseases and abnormalitiesmissense11Q23.1Risk factors in diseasesCANCER-RISKMLH1Articleaberrant splicing03 medical and health sciencesAGEmedicineGenetic predispositionddc:610<i>MSH2</i>Lynchin oireyhtymäpenetrance030304 developmental biologyGenetic testingMLH1; MSH2; penetrance; cancer incidence; truncating; missense; aberrant splicing; Lynch syndromeperinnölliset tauditbusiness.industryMUTATIONSHMSH2Cancernutritional and metabolic diseasesmedicine.diseasedigestive system diseasesMSH2Lynch syndromeMSH23121 General medicine internal medicine and other clinical medicine<i>MLH1</i>businesstruncating
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Effects of Gestational Diabetes Mellitus on Cholesterol Metabolism in Women with High-Risk Pregnancies: Possible Implications for Neonatal Outcome

2022

Metabolic disorders in pregnancy, particularly gestational diabetes mellitus (GDM), are associated with an increased risk for adverse pregnancy outcome and long-term cardiometabolic health of mother and child. This study analyzed changes of serum cholesterol synthesis and absorption markers during the course of high-risk pregnancies, with respect to the development of GDM. Possible associations of maternal lipid biomarkers with neonatal characteristics were also investigated. The study included 63 women with high risk for development of pregnancy complications. Size and proportions of small low-density (LDL) and high-density lipoprotein (HDL) particles were assessed across trimesters (T1&nd…

cholesterol synthesis and absorptionEndocrinology Diabetes and Metabolismhigh-risk pregnancy; gestational diabetes; cholesterol synthesis and absorption; LDL and HDL particles; neonatal outcomeLDL and HDL particles cholesterol synthesis and absorption gestational diabetes high-risk pregnancy neonatal outcomehigh-risk pregnancygestational diabetesLDL and HDL particlesMolecular BiologyBiochemistryneonatal outcome
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Severe Perinatal Hypoxic-Ischemic Brain Injury Induces Long-Term Sensorimotor Deficits, Anxiety-Like Behaviors and Cognitive Impairment in a Sex-, Ag…

2019

Perinatal brain injury (PBI) leads to neurological disabilities throughout life, from motor deficits, cognitive limitations to severe cerebral palsy. Yet, perinatal brain damage has limited therapeutic outcomes. Besides, the immature brain of premature children is at increased risk of hypoxic/ischemic (HI) injury, with males being more susceptible to it and less responsive to protective/therapeutical interventions. Here, we model in male and female C57BL/6 mice, the impact of neonatal HI and the protective effects of neonatal handling (NH), an early life tactile and proprioceptive sensory stimulation. From postnatal day 1 (PND1, modeling pre-term) to PND21 randomized litters received either…

cognitionsensory stimulationCognitive NeurosciencePhysiologyBrain damageCorpus callosumlcsh:RC321-571Cerebral palsy03 medical and health sciencesBehavioral Neuroscience0302 clinical medicineAtrophyCognitionmedicinesexAnimal modelneonatal hypoxic ischemic injurylcsh:Neurosciences. Biological psychiatry. Neuropsychiatry030304 developmental biologyOriginal Research0303 health sciencesBehaviorSensory stimulation therapyNeocortexbusiness.industrybehaviorPutamenanimal modelNeophobiagender medicineNeonatal handlingmedicine.diseaseSensory stimulationmedicine.anatomical_structureNeuropsychology and Physiological PsychologyNeonatal hypoxic ischemic injuryneonatal handlingSexGender medicinemedicine.symptombusiness030217 neurology & neurosurgeryNeuroscienceFrontiers in Behavioral Neuroscience
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SULL'IMPIEGO SPERIMENTALE DI UN COLLANTE BIOLOGICO NELLE ANASTOMOSI INTESTINALI NEL RATTO IN ACCRESCIMENTO

1980

The problems that arise in the preparation of the anastomoses of channelicular organs have not found a unique solution. In fact, when it is necessary to proceed to the synthesis of very small gauge hollow organs as in the accreting subjects (infants) the risk of formation of a stenosis is always present despite the various techniques practiced. In recent years several experimental researches have been carried out in order to verify the validity of biological adhesives in intestinal anastomoses in rapidly growing animals. For this purpose we have chosen the rat whose rapidity of somatic growth permits an evaluation in times contained

collanti biologici chirurgia sperimentale su ratti in accrescimento.Experimental micro-surgery in rats intesinal anastomosis Isobutil-2-cianoacrilatoChirurgia pediatrfica e neonataleSettore MED/20 - Chirurgia Pediatrica E Infantileanastomosi intestinali
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Does Hysteroscopic Dissection of Partial Uterine Septum Represent a Risk Factor for Placental Abnormalities in Subsequent Pregnancy Compared with Con…

2022

Background: Hysteroscopic septum dissection (HSD) is thought to improve fertility and pregnancy outcomes. However, the available literature suggests that uterine surgery can cause placental abnormalities in subsequent pregnancies. Methods: A case–control study was performed at the University Medical Center of Ljubljana, Department of Human Reproduction, from 1 January 2016 to 31 December 2018. The primary outcome was the association between HSD and the occurrence of placental abnormalities. We included women who underwent HSD due to infertility. Age-matched women who underwent hysteroscopic surgery for other issues were considered as controls. In addition, we divided the groups according to…

congenital uterine anomalies; uterine septum dissection; placental abnormalities; neonatal outcome; IVF/ICSI; hysteroscopy; complicationsComplicationsUterine septum dissectionIVF/ICSIGeneral MedicineCongenital uterine anomaliesHysteroscopyNeonatal outcomeSettore MED/40 - Ginecologia E OstetriciaPlacental abnormalities
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