Search results for "Neste"

showing 10 items of 639 documents

Outcomes of Patients Presenting with Mild Acute Respiratory Distress Syndrome: Insights from the LUNG SAFE Study

2019

Editor's Perspective What We Already Know about This Topic Hospital mortality in acute respiratory distress syndrome is approximately 40%, but mortality and trajectory in "mild" acute respiratory distress syndrome (classified only since 2012) are unknown, and many cases are not detected What This Article Tells Us That Is New Approximately 80% of cases of mild acute respiratory distress syndrome persist or worsen in the first week; in all cases, the mortality is substantial (30%) and is higher (37%) in those in whom the acute respiratory distress syndrome progresses Background: Patients with initial mild acute respiratory distress syndrome are often underrecognized and mistakenly considered …

MaleInternationalityRespiratory Distress Syndrome Adultadult respiratory distress syndromeMiddle AgedSeverity of Illness IndexPatient Outcome AssessmentProspective StudieAnesthesiology and Pain MedicineSettore MED/41 - ANESTESIOLOGIAARDSFemaleHospital MortalityAcute Respiratory Distress SyndromeHuman
researchProduct

Intracranial pressure monitoring in patients with acute brain injury in the intensive care unit (SYNAPSE-ICU): an international, prospective observat…

2021

Background: The indications for intracranial pressure (ICP) monitoring in patients with acute brain injury and the effects of ICP on patients’ outcomes are uncertain. The aims of this study were to describe current ICP monitoring practises for patients with acute brain injury at centres around the world and to assess variations in indications for ICP monitoring and interventions, and their association with long-term patient outcomes. Methods: We did a prospective, observational cohort study at 146 intensive care units (ICUs) in 42 countries. We assessed for eligibility all patients aged 18 years or older who were admitted to the ICU with either acute brain injury due to primary haemorrhagic…

MaleIntracranial PressureGlasgow Outcome ScaleMalalties cerebralsintensive care unitlaw.inventionCohort Studies0302 clinical medicinelawBrain Injuries TraumaticMedicineacute brain injuryProspective StudiesProspective cohort studyUnitats de cures intensivesIntracranial pressureIntensive care unitsGlasgow Outcome ScaleMiddle AgedIntensive care unitIntensive Care UnitsHypertensionIntracranial pressure monitoringFemaleHipertensióBrain diseasesAdultmedicine.medical_specialtyCritical CareTraumatic brain injuryIntracranial pressure monitoring brain injury03 medical and health sciencesInternal medicineIntensive careSettore MED/41 - ANESTESIOLOGIAHumansGlasgow Coma ScaleAgedMonitoring Physiologicbusiness.industryGlasgow Coma Scale030208 emergency & critical care medicineICPIntracranial pressure monitoringmedicine.diseaseBrain InjuriesNeurology (clinical)Intracranial Hypertensionbusiness030217 neurology & neurosurgery
researchProduct

Chromium Exposure and Risk of Cardiovascular Disease in High Cardiovascular Risk Subjects　― Nested Case-Control Study in the Prevention With Mediterr…

2017

BACKGROUND: Epidemiological data on chromium (Cr) exposure and the risk of cardiovascular disease (CVD) are still limited. Toenail Cr level (TCL) provides a time-integrated measure reflecting long-term Cr exposure. We measured TCL to assess the hypothesis that long-term Cr exposure was inversely associated with incident CVD in a population at high risk for CVD.Methods and Results:The associations between TCL and CVD were evaluated in a case-control study nested within the "PREvención con DIeta MEDiterránea" (PREDIMED) trial. We randomly selected 147 of the 288 patients diagnosed with CVD during follow-up and matched them on age and sex to 271 controls. Instrumental neutron activation analys…

MaleMetalls -- Efectes fisiològicsChromiumPREDIMED0301 basic medicineMediterranean diet010501 environmental sciencesDiet Mediterranean01 natural sciences03 medical and health sciencesMediterranean cookingRisk FactorsCuina mediterràniaHumansMedicineToenail biomarkerAged0105 earth and related environmental sciencesAged 80 and overDiabetis030109 nutrition & dieteticsMalalties cardiovascularsbusiness.industryDiabetesGeneral MedicineMiddle AgedAtencion primariaCardiovascular diseasePredimedDietCardiovascular DiseasesSpainCase-Control StudiesNested case-control studyDietaFemaleCardiology and Cardiovascular MedicinebusinessHumanitiesOlive oilCirculation Journal
researchProduct

Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project

2019

Contains fulltext : 206779.pdf (Publisher’s version ) (Open Access) BACKGROUND: The objective of this study was to assess the cumulative incidence of invasive candidiasis (IC) in intensive care units (ICUs) in Europe. METHODS: A multinational, multicenter, retrospective study was conducted in 23 ICUs in 9 European countries, representing the first phase of the candidemia/intra-abdominal candidiasis in European ICU project (EUCANDICU). RESULTS: During the study period, 570 episodes of ICU-acquired IC were observed, with a cumulative incidence of 7.07 episodes per 1000 ICU admissions, with important between-center variability. Separated, non-mutually exclusive cumulative incidences of candide…

MaleOutcome Assessmentlnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]MULTICENTERCritical Care and Intensive Care Medicinelaw.invention610 Medical sciences Medicine0302 clinical medicineRetrospective StudieRisk FactorslawOutcome Assessment Health CareEPIDEMIOLOGYMedicineCumulative incidencePREDICTORSCandidaMedicine(all)Cross InfectionIncidenceIncidence (epidemiology)lcsh:Medical emergencies. Critical care. Intensive care. First aidCandidiasisMiddle AgedIntensive care unitEuropeIntensive Care UnitsAbdominal candidiasis; Candida; Candidemia; Candidiasis; ICU; Incidence; Aged; Candidiasis Invasive; Cross Infection; Europe; Female; Humans; Incidence; Intensive Care Units; Male; Middle Aged; Outcome Assessment Health Care; Retrospective Studies; Risk FactorsCandidiasiFemaleSOFA scoreLife Sciences & BiomedicineHumanAbdominal candidiasismedicine.medical_specialtyInvasiveIntensive Care Unit610Abdominal candidiasis Candida Candidemia Candidiasis ICU Incidence03 medical and health sciencesCritical Care MedicineGeneral & Internal MedicineIntensive careSettore MED/41 - ANESTESIOLOGIAMANAGEMENTHumansCandidiasis InvasiveAgedRetrospective StudiesScience & TechnologyAbdominal candidiasis; Candida; Candidemia; Candidiasis; ICU; Incidencebusiness.industrySeptic shockINTRAABDOMINAL CANDIDIASISResearchCandidemia030208 emergency & critical care medicineRetrospective cohort studylcsh:RC86-88.9Odds ratiomedicine.diseaseHealth Carelnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4]ICUEmergency medicineAbdominal candidiasibusinessCritical Care
researchProduct

The use of fentanyl buccal tablets for breakthrough pain by using doses proportional to opioid basal regimen in a home care setting.

2013

Abstract The dose of rapid onset opioids to be given for breakthrough cancer pain (BTcP) is controversial. Dose proportional to the basal opioid regimen seem to be safe and effective in hospital units. However, data in other less protected settings, like home care, are lacking. The aim of this open-label study was to assess the efficacy and safety in a group of patients with BTcP followed at home, after giving a dose of fentanyl buccal tablets (FBT) proportional to the opioid basal regimen, skipping the steps for dose titration. Consecutive patients admitted to a home care program presenting BTcP episodes and receiving stable doses of opioids for background pain were selected. Data from fou…

MalePain medicineSettore MED/41 - AnestesiologiaOpioidSettore MED/42 - Igiene Generale E ApplicataHome careFentanylDose-Response RelationshipBuccalBreakthrough-episodic painNeoplasmsmedicine80 and overHumansCancer painAdverse effectAgedPain MeasurementAged 80 and overAnalgesicsDose-Response Relationship Drugbusiness.industryBreakthrough PainAdministration BuccalBuccal administrationMiddle AgedFentanyl buccal tabletHome Care ServicesAnalgesics OpioidOpioidsFentanylRegimenTreatment OutcomeBasal (medicine)OpioidOncologyCancer pain; Breakthrough-episodic pain; Fentanyl buccal tablet; Opioids; Home careAnesthesiaAdministrationFemaleBreakthrough-episodic pain; Cancer pain; Fentanyl buccal tablet; Home care; Opioids; Administration Buccal; Aged; Aged 80 and over; Analgesics Opioid; Breakthrough Pain; Dose-Response Relationship Drug; Female; Fentanyl; Home Care Services; Humans; Male; Middle Aged; Neoplasms; Pain Measurement; Tablets; Treatment Outcome; OncologyDrugCancer painbusinessmedicine.drugTablets
researchProduct

The use of sublingual fentanyl for breakthrough pain by using doses proportional to opioid basal regimen.

2013

Abstract OBJECTIVE: The aim of this study was to prospectively assess the efficacy and safety of sublingual fentanyl (SLF) in doses proportional to opioid doses used for background analgesia for the treatment of BTP of cancer patients. METHODS: A sample of patients admitted to an acute palliative care unit, presenting breakthrough pain (BTP) episodes and receiving stable doses of opioids for background pain was selected to assess the efficacy and safety of SLF used in doses proportional to the basal opioid regimen used for the management of BTP. For each patient, data from four consecutive episodes were collected. For each episode, nurses collected changes in pain intensity and adverse effe…

MalePalliative careAdministration SublingualSettore MED/41 - AnestesiologiaMANAGEMENT BTPSettore MED/42 - Igiene Generale E ApplicataFentanylQuality of lifemedicineHumansAdverse effectAgedPain Measurementbreakthrough pain; FENTANYL; MANAGEMENT BTPbusiness.industryPalliative CareFENTANYLGeneral MedicineMiddle Agedbreakthrough painAnalgesics OpioidRegimenTreatment OutcomeBasal (medicine)OpioidAnesthesiaQuality of LifeFemalebusinessCancer painmedicine.drug
researchProduct

A nested case–control study: personal, social and environmental correlates of vigorous physical activity in adolescents with asthma

2014

Objective: Physical activity (PA) is associated with health benefits. Children and adolescents with asthma may be limited in their PA, particularly at vigorous intensity due to asthma symptoms or poor psychological adjustment to asthma. We aimed to investigate if self-perceived competence, enjoyment, support from others and social-physical environment were associated with vigorous physical activity (VPA) and secondarily to assess if such associations were modified by asthma and asthma severity. Methods: Data from a nested case–control study at 13 years of age within the birth-cohort Environment and Childhood Asthma Study were compiled from 95 participants with and 79 without asthma. The par…

MaleParentsPulmonary and Respiratory Medicinemedicine.medical_specialtyAdolescentHealth BehaviorcompetencePhysical activityEnvironmentSeverity of Illness IndexPeer GroupMetabolic equivalentsocial environmentSocial supportSex Factorsimmune system diseasesMetabolic EquivalentmedicineHumansImmunology and AllergyBody Weights and MeasuresChildExerciseCompetence (human resources)Asthmabusiness.industrySocial environmentsocial supportmedicine.diseaseFacultyAsthmaSelf Efficacyrespiratory tract diseasesPeer reviewCase-Control Studiesphychological adjustmentPediatrics Perinatology and Child HealthNested case-control studyPhysical therapyFemalehealth benefitsbusinessClinical psychologyJournal of Asthma
researchProduct

Epidemiological characteristics, practice of ventilation, and clinical outcome in patients at risk of acute respiratory distress syndrome in intensiv…

2016

Background Scant information exists about the epidemiological characteristics and outcome of patients in the intensive care unit (ICU) at risk of acute respiratory distress syndrome (ARDS) and how ventilation is managed in these individuals. We aimed to establish the epidemiological characteristics of patients at risk of ARDS, describe ventilation management in this population, and assess outcomes compared with people at no risk of ARDS. Methods PRoVENT (PRactice of VENTilation in critically ill patients without ARDS at onset of ventilation) is an international, multicentre, prospective study undertaken at 119 ICUs in 16 countries worldwide. All patients aged 18 years or older who were rece…

MalePediatricsARDSmedicine.medical_treatmentlaw.inventionPositive-Pressure Respiration0302 clinical medicinelawRisk FactorsPrevalenceventilator–induced lung injuryProspective StudiesHospital MortalityProspective cohort studyTidal volumeeducation.field_of_studyRespiratory Distress SyndromeAcute respiratory distress syndrometidal volumeARDS critically ill ventilationMiddle AgedIntensive care unitIntensive Care UnitsCritical IllneFemaleHumanPulmonary and Respiratory Medicinemedicine.medical_specialtyCritical IllnessPopulationIntensive Care UnitLung injurymechanical ventilationNO03 medical and health sciencesIntensive caremedicineAcute respiratory distress syndrome mechanical ventilation ventilator–induced lung injury tidal volume positive end–expiratory pressureHumansMED/41 - ANESTESIOLOGIAeducationAgedMechanical ventilationbusiness.industryRisk FactorRespiratory Distress Syndrome Adult030208 emergency & critical care medicinemedicine.diseaseRespiration ArtificialMechanical ventilation Acute respiratory failure Acute respiratory distress syndromeProspective Studie030228 respiratory systemEmergency medicinepositive end–expiratory pressurebusiness
researchProduct

Epidemiology, practice of ventilation and outcome for patients at increased risk of postoperative pulmonary complications:LAS VEGAS - An observationa…

2017

BACKGROUND Limited information exists about the epidemiology and outcome of surgical patients at increased risk of postoperative pulmonary complications (PPCs), and how intraoperative ventilation was managed in these patients. OBJECTIVES To determine the incidence of surgical patients at increased risk of PPCs, and to compare the intraoperative ventilation management and postoperative outcomes with patients at low risk of PPCs. DESIGN This was a prospective international 1-week observational study using the ‘Assess Respiratory Risk in Surgical Patients in Catalonia risk score’ (ARISCAT score) for PPC for risk stratification. PATIENTS AND SETTING Adult patients requiring intraoperative venti…

MalePediatricsInternationalityRESPIRATORY-DISTRESS-SYNDROME0302 clinical medicinePostoperative Complications030202 anesthesiologyRisk FactorsEpidemiologyABDOMINAL-SURGERY80 and overMedicine and Health SciencesGeneral anaesthesiaAnesthesiaEND-EXPIRATORY-PRESSUREBERLIN DEFINITION030212 general & internal medicineProspective StudiesProspective cohort studyLungAged 80 and overFramingham Risk ScoreIncidence (epidemiology)RespirationMiddle AgedTreatment OutcomeArtificialFemalePRACTICE PATTERNSHumanmedicine.medical_specialtymechanical ventilation ; prospective observational study ; Intensive careAnesthesia GeneralNONCARDIOTHORACIC SURGERYNOAged; Aged 80 and over; Anesthesia General; Cross-Sectional Studies; Female; Humans; Intraoperative Care; Lung; Male; Middle Aged; Postoperative Complications; Prospective Studies; Respiration Disorders; Respiration Artificial; Risk Factors; Tidal Volume; Treatment Outcome; Internationality; Anesthesiology and Pain MedicineACUTE LUNG INJURY03 medical and health sciencesGENERAL-ANESTHESIAInternal medicinemedicineJournal ArticleTidal VolumeHumansMED/41 - ANESTESIOLOGIAGeneralAgedCross-Sectional StudieIntraoperative Carebusiness.industryRisk FactorRespiration DisorderRespiration DisordersRespiration ArtificialConfidence intervalPROTECTIVE MECHANICAL VENTILATIONProspective StudieAnesthesiology and Pain MedicineCross-Sectional StudiesRelative riskMAJOR NONCARDIAC SURGERYPostoperative ComplicationbusinessAbdominal surgery
researchProduct

Epidemiology and Characteristics of Episodic Breathlessness in Advanced Cancer Patients. An Observational Study

2016

Abstract Context Episodic breathlessness is a relevant aspect in patients with advanced cancer. Objectives The aim of this study was to assess the different aspects of this clinical phenomenon. Methods A consecutive sample of patients with advanced cancer admitted to different settings for a period of six months was surveyed. The presence of background breathlessness and episodic breathlessness, their intensity (numerical scale 0–10), and drugs used for treatment were collected. Factors inducing episodic breathlessness and its influence on daily activities were investigated. Results Of 921 patients, 29.3% ( n  = 269) had breathlessness and 134 patients (49.8%) were receiving drugs for backg…

MalePediatricsmedicine.medical_specialtyPalliative careActivities of daily livingTime FactorsEpisodic breathlessneSettore MED/41 - AnestesiologiaContext (language use)advanced cancer; dyspnea; Episodic breathlessness; opioids; palliative care; Anesthesiology and Pain Medicine; Neurology (clinical); Nursing (all)2901 Nursing (miscellaneous)DiseaseComorbidityepisodic breathlessness; advanced cancer; dyspnea; opioids; palliative care03 medical and health sciencesPulmonary Disease Chronic Obstructive0302 clinical medicineNeoplasmsEpidemiologyActivities of Daily LivingmedicinePrevalenceHumansadvanced cancer030212 general & internal medicineKarnofsky Performance StatusGeneral NursingNursing (all)2901 Nursing (miscellaneous)Agedpalliative careEpisodic breathlessnessbusiness.industryEpisodic breathlessness; advanced cancer; dyspnea; opioids; palliative careopioidsCardiovascular Agentsrespiratory systemMiddle Ageddyspneamedicine.diseaseComorbidityAnesthesiology and Pain Medicine030220 oncology & carcinogenesisCardiovascular agentMultivariate AnalysisopioidObservational studyFemaleNeurology (clinical)business
researchProduct