Search results for "Network"
showing 10 items of 7718 documents
Exploring the network of odours shared by an aroma blending mixture
2019
International audience; The first step of odour perception is an interaction between odorants and olfactory receptors [1]. Moreover, odours perceived in our environment are mainly the result of mixtures of odorants; however, the specific mechanisms involved in their processing remain poorly understood [2]. In previous studies performed at INRA-CSGA [3], the perception of a mixture of ethyl isobutyrate (Et-iB, strawberry-like odour, STR) and ethyl maltol (Et-M, caramel-like odour, CAR) was investigated in comparison with a reference (allyl hexanoate, Al-H, pineapple-like odour, PNA) chosen to evoke an odour close to the one expected in the mixture. The binary specific mixture of Et-iB and Et…
Exploring the odorant and molecular characteristics of molecules sharing the odour notes of an aroma blending mixture
2021
Online event (Live and on-demand); International audience; To perceive a huge number of odors from few hundreds ORs, the human olfactory system encodes odor identities by an olfactory scheme whereby one olfactory receptor (OR) recognizes multiple odorants while one odorant activates different combinations of ORs [1, 2]. Odors perceived in our environment are mainly the result of mixtures of odorants, but the specific mechanisms involved in their processing remain poorly understood [3]. In previous studies performed at INRAE-CSGA [4], the perception of a mixture of ethyl isobutyrate (Et iB, strawberry-like odor, STR) and ethyl maltol (Et-M, caramel-like odor, CAR) was investigated in compari…
Thaxtomin A-induced defense responses in Arabidopsis thaliana cells require an early Ca2+ influx
2008
International audience
LXR, prostate cancer and cholesterol: the Good, the Bad and the Ugly.
2012
International audience; Cholesterol is a fundamental molecule for life. Located in the cell membrane, this sterol participates to the cell signaling of growth factors. Inside the cell it can be converted in hormones such as androgens or modulate the immune response. Such important functions could not be solely dependent of external supply by diet hence de novo synthesis could occur from acetate in almost all mammalian cells. If a deficiency in cholesterol sourcing leads to development troubles, overstocking has been associated to various diseases such as atherosclerosis and cancers. Cholesterol homeostasis should thus be tightly regulated at the uptake, de novo synthesis, storage and export…
Biotic homogenisation in bird communities leads to large‐scale changes in species associations
2021
The impact of global change on biodiversity is commonly assessed in terms of changes in species distributions, community richness and community composition. Whether and how much associations between species are also changing is much less documented. In this study, we quantify changes in large-scale patterns of species associations in bird communities in relation to changes in species composition. We use network approaches to build three community-aggregated indices reflecting complementary aspects of species association networks. We characterise the spatio–temporal dynamics of these indices using a large-scale and high-resolution dataset of bird co-abundances of 109 species monitored for 17…
In vitro simulation of spiral waves in cardiomyocyte networks using multi-electrode array technology
2009
International audience; We aimed thus to provide new insights into the cellular origin of the fibrillation phenomenon by exploring the impulse propagation between cardiac myocytes in confluent monolayers of cultured cardiomyocytes (CM),
The multiple facets of Cajal-Retzius neurons.
2021
ABSTRACTCajal-Retzius neurons (CRs) are among the first-born neurons in the developing cortex of reptiles, birds and mammals, including humans. The peculiarity of CRs lies in the fact they are initially embedded into the immature neuronal network before being almost completely eliminated by cell death at the end of cortical development. CRs are best known for controlling the migration of glutamatergic neurons and the formation of cortical layers through the secretion of the glycoprotein reelin. However, they have been shown to play numerous additional key roles at many steps of cortical development, spanning from patterning and sizing functional areas to synaptogenesis. The use of genetic l…
Influence de l'état protéique sur la dynamique de séparation de phase et de gélification dans un système ternaire aqueux à base de protéines de pois …
2012
Two aqueous systems at 20°C in 0.1 M NaCl and pH 7.2 containing globular pea proteins and sodium alginate were investigated in this study. First, phase behavior of (i) either low-denatured mixed globulins or (ii) their thermally pre-aggregated counterparts - alginate mixtures was compared using a multi-scale approach, by means of phase diagram and microstructure analysis by confocal microscopy. Thermodynamic incompatibility was the main driving force leading to phase separation within the mixtures, which presented according to their initial biopolymer composition both different morphological and time-evolution features of coexisting phases. Thereafter, a cold-set gelation for each system wa…
Fragmentation des habitats et interactions hôtes-parasites
2021
Habitat fragmentation is one of the main threats to global biodiversity and despite an abundant literature on the impact of fragmentation on species abundance and diversity, the consequences of this global change in terms of ecological and evolutionary processes remain poorly understood. Beyond their direct contribution to biodiversity, as species-rich category of organisms, parasites could be involved in biodiversity change as key actors of ecological and evolutionary processes. The present work aims to understand the effect of forest fragmentation on host-parasite interactions. It is based on a large sampling carried out in the Lesser Antilles and in French Guiana, and allowing the obtent…
Étude des interconnexions dans les réseaux de régulation de Listeria monocytogenes en réponse aux conditions de l'environnement
2019
The facultative intracellular pathogen Listeria monocytogenes is a highly adaptable organism widely distributed in the environment. The ingestion of food contaminated with L. monocytogenes by at-risk individuals can ultimately lead to listeriosis, one of the leading causes of food-borne fatalities in developed countries. Regulatory networks are crucial for the adaptation and survival of this pathogen. The accessory gene regulator (Agr) system has been shown to be involved in virulence, biofilm formation, and survival of L. monocytogenes, affecting the transcription of over 700 genes. The alternative sigma factor Sigma B (σB) controls the general stress response in L. monocytogenes, regulati…