Search results for "Neumonia"

No klīniskajiem paraugiem izdalīto Streptococcus pneumoniae virulences faktori un rezistence pret antibakteriālajiem līdzekļiem

2020

Ievads: Latvijā un Pasaulē aktuāla problēma ir Streptococcus pneumoniae baktērijas rezistence, kas izveidojusies pret antibakteriālajiem līdzekļiem. Rezistento Streptococcus pneumoniae celmu skaits palielinās ar katru gadu. Preventīvie pasākumi, kas samazinātu rezistences incidenci ir svarīga atbildīga un piesardzīga antibakteriālo līdzekļu izmantošana cilvēku veselības uzlabošanai un pacientu informētība, izpratne par Streptococcus pneumoniae rezistenci. Darba mērķi: Noteikt Streptecoccus pneumoniae jutību pret antibakteriālajiem līdzekļiem, kas iegūti no klīniskā materiāla paraugiem. Materiāli un metodes: Pētījums veikts RAKUS stacionārs ‘’Tuberkulozes un plaušu slimību centrs’’ klīnikas …

No klīniskā materiāla izdalīto Streptococcus pneumoniae jutība pret antibakteriālajiem līdzekļiem

2016

Nozīmīga sabiedrības veselības problēma ir baktēriju rezistence pret antibakteriālajiem līdzekļiem. Pasaulē parādās arvien jauni pret antibakteriālajiem līdzekļiem rezistenti S. pneumoniae celmi. Tas galvenokārt, saistīts ar antibakteriālo līdzekļu nepareizu pielietošanu un plaša spektra preparātu lietošanu, kad ir iespējams izmantot šaura spektra antibakteriālus līdzekļus. Darba mērķis: Noteikt S. pneumoniae jutību pret antibakteriālajiem līdzekļiem, celmiem, kas izdalīti no klīniskā materiāla. Darba uzdevumi: Veikt laboratorijā identificēto S. pneumoniae jutības testus pret antibakteriālajiem līdzekļiem, pielietojot BBLTM DDT un BBLTM E – testu, analizēt statistiskos datus, izmantojot Mic…

One is not enough: On the effects of reference genome for the mapping and subsequent analyses of short-reads.

2020

Mapping of high-throughput sequencing (HTS) reads to a single arbitrary reference genome is a frequently used approach in microbial genomics. However, the choice of a reference may represent a source of errors that may affect subsequent analyses such as the detection of single nucleotide polymorphisms (SNPs) and phylogenetic inference. In this work, we evaluated the effect of reference choice on short-read sequence data from five clinically and epidemiologically relevant bacteria (Klebsiella pneumoniae, Legionella pneumophila, Neisseria gonorrhoeae, Pseudomonas aeruginosa and Serratia marcescens). Publicly available whole-genome assemblies encompassing the genomic diversity of these species…

Specialized subsets of innate-like T cells and dendritic cells protect from lethal pneumococcal infection in the lung

2021

SummaryInnate-like T cells, including invariant natural killer T (iNKT) cells, mucosal-associated invariant T (MAIT) cells and γδ T cells, are present in various barrier tissues, including the lung. They carry out protective responses during infections, but the mechanisms for protection are not completely understood. Here, we investigated their roles during pulmonary infection with Streptococcus pneumoniae. Following infection, innate-like T cells rapidly increased in lung tissue, in part through recruitment, but TCR activation and cytokine production occurred mostly in IL-17-producing NKT17 and γδ T cells. NKT17 cells were preferentially located outside the vasculature prior to infection, …

Telemedicine and Remote Screening for COVID-19 in Inflammatory Bowel Disease Patients: Results From the SoCOVID-19 Survey

2020

Lung Ultrasonography – A Paraclinical Investigation Promoter in Community-Acquired Pneumonia Diagnosis in Children

2019

Abstract Lung ultrasonography is an excellent alternative to chest radiography, with better sensitivity, specificity, positive and negative predictive values and, finally, with better accuracy. The lung ultrasonography is proven to be useful in trying to reduce the request of chest radiography. In the opinion of most specialists, lung ultrasonography is recommended to be a valuable tool for the diagnosis of community-acquired pneumonia in children. Considering the fact that clinical examination remains essential because it suspects the diagnosis, the evolution does not require radiologic follow-up, also the pathologic findings at the clinical examination may change over the course of a day,…

Hochauflösende Computertomographie der Lunge bei neutropenischen Patienten mit Fieber

1996

Purpose To determine the sensitivity and clinical impact of high-resolution CT (HRCT) of the lung in febrile neutropenic patients under antibiotic therapy. Material and methods Chest X-ray and HRCT were prospectively performed to exclude pneumonia in 34 patients (53 examinations) suffering from febrile neutropenia following antitumor therapy. Diagnosis was confirmed by bronchoalveolar lavage or sputum cultures. Results Chest X-ray showed pneumonia in 13/53 examinations, in 12/13 a micro-organism was found. HRCT demonstrated pneumonia in 39/53, in 31/39 a micro-organism was found. All cases with positive cultures showed suspicious HRCT findings. Changes in antibiotic treatment resulted in fi…

Virtual meetings and social isolation in COVID-19 times: transposable barriers

2020

E.coli, K.pneumoniae un P. aeruginosa antimikrobiālā rezistence urīnceļu infekcijās

2018

Fons: 2015. gadā PVO ieviesa Globālo mikrobu rezistences uzraudzības sistēmu (GLASS). 2017. gadā to pirmoreiz ieviesa Latvijā. Mērķi: Raksturot pašreizējo situāciju attiecībā uz antimikrobiālo rezistenci, multirezistenci kā arī ESBL (plaša spektra beta laktamāzes) producētājus urīnceļu infekcijām, ko izraisa E. coli, K. pneumoniae un P. aeruginosa un analizēt saistību ar pacienta vecumu, dzimumu un infekcijas izcelsmi. Materiāli un metodes: Kopskaitā tika analizēti 924 urīna paraugi no Paula Stradiņa Klīniskās universitātes slimnīcas, 2016. gadā (731 — E. coli, 147 — K. pneumoniae, 46 — P. aeruginosa). Rezultāti: E. coli rezistences procentuālās daļas: amikacīns: 0,3%, ceftazidīms: 13,8%, c…

Impact of the COVID-19 pandemic on urological practice in emergency departments in Italy

2020

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) and the disease it causes, coronavirus disease 2019 (COVID-19), are causing a rapid and tragic health emergency worldwide [1,2]. Italy was the first European country to experience a virus outbreak, starting on 21 February 2020. It resulted in a national quarantine, and the official lockdown of the country’s non-essential businesses and services began on 9 March 2020. Although several reports are available in the literature providing recommendations for the reorganization of clinical and surgical activities [3–7], to our knowledge, no data are available on the effects of the COVID-19 pandemic on the outcomes of other medical conditi…