Search results for "Neumonia"
showing 10 items of 657 documents
Neumonía adquirida en la comunidad: tratamiento ambulatorio y prevención
2015
Resumen: La neumonía adquirida en la comunidad (NAC) en la edad pediátrica ha sufrido, en la última década, una serie de cambios epidemiológicos, clínicos, etiológicos y de resistencias a antibióticos, que obligan a replantear su abordaje terapéutico. En este documento, dos de las principales sociedades de especialidades pediátricas involucradas en el diagnóstico y tratamiento de esta entidad, como son la Sociedad Española de Infectología Pediátrica y la Sociedad Española de Neumología Pediátrica, así como el Comité Asesor de Vacunas de la AEP, proponen unas pautas consensuadas de tratamiento y prevención, con el fin de proporcionar a todos los pediatras una guía actualizada. En esta primer…
SARS-CoV-2 RNA in wastewater anticipated COVID-19 occurrence in a low prevalence area
2020
Preprint disponible en http://hdl.handle.net/10261/209125
Relative Frequencies and Significance of Faecal Coliforms as Indicators Related to Water Temperature
1983
Summary The faecal coliforms at different sites of a hypereutrophic lake near Valencia (Albufera) were identified and their relative amounts established along an annual cycle. Using lauryl tryptose broth at 35°C, followed by incubation at 44.4°C in 2% brilliant green bile, Escherichia coli and Klebsiella pneumoniae are practically the only coliforms present. A positive correlation was found between the water temperature and the relative amount of these two coliforms: K. pneumoniae predominates at high water temperatures, whereas E. coli shows preponderance during the cold period. The role of K. pneumoniae as the only faecal indicator under the circumstances described in the work is emphasiz…
Who can go back to work when the COVID-19 pandemic remits?
2020
AbstractThis paper seeks to determine which workers affected by lockdown measures can return to work when a government decides to apply lockdown exit strategies. This system, which we call Sequential Selective Multidimensional Decision (SSMD), involves deciding sequentially, by geographical areas, sectors of activity, age groups and immunity, which workers can return to work at a given time according to the epidemiological criteria of the country as well as that of a group of reference countries, used as a benchmark, that have suffered a lower level of lockdown de-escalation strategies. We apply SSMD to Spain, based on affiliation to the Social Security system prior to the COVID-19 pandemic…
To defer or not to defer? A German longitudinal multicentric assessment of clinical practice in urology during the COVID-19 pandemic
2020
PLOS ONE 15(9), e0239027 (2020). doi:10.1371/journal.pone.0239027
Genome Sequence of Klebsiella pneumoniae KpQ3, a DHA-1 β-Lactamase-Producing Nosocomial Isolate.
2012
ABSTRACT Klebsiella pneumoniae KpQ3 is a multidrug-resistant isolate obtained from a blood culture of a patient in a burn unit in the Hospital Universitario La Paz (Madrid, Spain) in 2008. The genome contains multiple antibiotic resistance genes, including a plasmid-mediated DHA-1 cephalosporinase gene.
COVID-19 Pandemic: Prevention and protection measures to be adopted at the workplace
2020
Introduction: SARS-CoV-2, identified in Wuhan, China, for the first time in December 2019, is a new viral strain, which has not been previously identified in humans; it can be transmitted both by air and via direct and indirect contact; however, the most frequent way it spreads is via droplets. Like the other viruses belonging to the same family of coronaviruses, it can cause from mild flu-like symptoms, such as cold, sore throat, cough and fever, to more severe ones such as pneumonia and breathing difficulties, and it can even lead to death. Since no effective specific drug therapy has been found yet, nor any vaccine capable of limiting the spread of this pathogen, it is important for way…
Antimikrobo līdzekļu menedžments stacionārā pnemonijas pacientiem
2019
Bakalaura darbs „Antimikrobo līdzekļu menedžments stacionārā pneimonijas pacientiem”. Tēmas aktualitāti nosaka elpošanas sistēmas saslimšanas gadījumu skaita palielināšanās, ar to saistīto antimikrobo līdzekļu lietošanas biežuma pieaugums un rezistento mikroorganismu attīstība. Darba mērķis ir noskaidrot antimikrobo līdzekļu menedžmenta realizāciju stacionārā pneimonijas pacientiem. Pētniecības metode – kvalitatīvā, instruments - intervija. Pētniecības jautājums: “Kā tiek realizēts antimikrobo līdzekļu terapijas menedžments pneimonijas pacientiem Intensīvās terapijas klīnikā?” Pētījuma rezultāti apliecina, ka Intensīvās terapijas klīnikā praktizējošās māsas izprot un īsteno antimikrobo līdz…
Looking for the best immune-checkpoint inhibitor in pre-treated NSCLC patients: An indirect comparison between nivolumab, pembrolizumab and atezolizu…
2017
Immune-checkpoint inhibitors represent the new standard of care in patients with advanced NSCLC who progressed after first-line treatment. This work aim to assess any difference in both efficacy and safety profiles among Nivolumab, Pembrolizumab and Atezolizumab in pre-treated NSCLC patients. Randomized clinical trials comparing immune-checkpoint inhibitor versus docetaxel in pre-treated patients with advanced NSCLC were included and direct comparison meta-analysis of selected trials have been performed. Subsequently the summary estimates of Nivolumab, Pembrolizumab and Atezolizumab emerging from the direct meta-analysis were selected to provide the pooled estimates of hazard ratio (HR) and…
Streptococcus pneumoniae sortāzes A inhibitoru atlase multirezistentu patogēnu izraisīto infekcijas slimību terapijai
2019
Darba mērķis ir atrast jaunas novatoriskas vielas, kas inhibē Grampozitīvās baktērijas Streptococcus pneumoniae transpeptidāzi sortāzi A. Šo inhibitoru atlasei tika izmantota rekombinanta S.pneumoniae sortāzes A katalītisko domēnu kodējoša konstrukcija bez N terminālā reģiona. Šāda rekombinanta transpeptidāze tika ekspresēta E.coli ekspresijas sistēmā un sintezētais proteīns izrādījās šķīstošs. Pēc attīrīšanas sortāze tika izmantota inhibitoru atlasei, izmantojot skrīningu, kas balstās uz fluorescences rezonanses enerģijas pārnesi (FRET). Pavisam tika pārbaudīti 966 potenciāli inhibitori savienojumi, no kuriem tālākām pārbaudēm tika atlasīti trīs labākie, kuri inhibēja IC50 testā izmantotās…