Search results for "Neurologi"

Pharmacotherapy, drug-drug interactions and potentially inappropriate medication in depressive disorders.

2021

Introduction The aim of this study was to describe the number and type of drugs used to treat depressive disorders in inpatient psychiatry and to analyse the determinants of potential drug-drug interactions (pDDI) and potentially inappropriate medication (PIM). Methods Our study was part of a larger pharmacovigilance project funded by the German Innovation Funds. It included all inpatients with a main diagnosis in the group of depressive episodes (F32, ICD-10) or recurrent depressive disorders (F33) discharged from eight psychiatric hospitals in Germany between 1 October 2017 and 30 September 2018 or between 1 January and 31 December 2019. Results The study included 14,418 inpatient cases.…

Disfunzioni sessuali, farmaci antiepilettici e profilo ormonale sierico negli uomini affetti da epilessia

2012

Razionale ed obiettivi: Le disfunzioni sessuali sono un problema relativamente comune nei pazienti di sesso maschile affetti da epilessia, la cui.prevalenza varia dal 38-71%. La loro eziologia non è conosciuta e potrebbe essere multifattoriale; possono essere implicati nella loro genesi sia l’epilessia che l’utilizzo di farmaci antiepilettici (FAE). L’assunzione di farmaci per la terapia dell’epilessia può essere all’origine della presenza di DS e di alterazioni ormonali e riproduttive in questa popolazione di pazienti. Lo scopo dello studio è valutare l’incidenza delle DS negli uomini con epilessia, valutando il tipo di epilessia, la frequenza delle crisi, il tipo di FAE utilizzato, il pro…

Disfunzioni sessuali, farmaci antiepilettici e profilo ormonale sierico negli uomini affetti da epilessia. Sexual disfunctions, antiepileptic drugs, …

2012

Sexual dysfunctions (SD) are a relatively common problem in men with epilepsy; the prevalence ranges from 38-71%. Etiology may be multifactorial and may involve both the epilepsy and the use of antiepileptic drugs. The purpose of this study was to evaluate the incidence of SD in epileptic men, assessing the type of epilepsy, seizures frequency, antiepileptic drugs used, the serum hormonal profile and the presence of psychiatric disorders.

FOLLOW-UP 2003-2008 DEI NATI VERY LOW BIRTH WEIGHT: ESITI NEUROLOGICI

2009

Fast Estimation of Diffusion Tensors under Rician noise by the EM algorithm

2016

Diffusion tensor imaging (DTI) is widely used to characterize, in vivo, the white matter of the central nerve system (CNS). This biological tissue contains much anatomic, structural and orientational information of fibers in human brain. Spectral data from the displacement distribution of water molecules located in the brain tissue are collected by a magnetic resonance scanner and acquired in the Fourier domain. After the Fourier inversion, the noise distribution is Gaussian in both real and imaginary parts and, as a consequence, the recorded magnitude data are corrupted by Rician noise. Statistical estimation of diffusion leads a non-linear regression problem. In this paper, we present a f…

Robust Conditional Independence maps of single-voxel Magnetic Resonance Spectra to elucidate associations between brain tumours and metabolites.

2020

The aim of the paper is two-fold. First, we show that structure finding with the PC algorithm can be inherently unstable and requires further operational constraints in order to consistently obtain models that are faithful to the data. We propose a methodology to stabilise the structure finding process, minimising both false positive and false negative error rates. This is demonstrated with synthetic data. Second, to apply the proposed structure finding methodology to a data set comprising single-voxel Magnetic Resonance Spectra of normal brain and three classes of brain tumours, to elucidate the associations between brain tumour types and a range of observed metabolites that are known to b…

Valmistuvien fysioterapeuttiopiskelijoiden käsityksiä neurologisesta fysioterapiasta

2014

TIIVISTELMÄ Anne Ryhänen (2014). Valmistuvien fysioterapeuttiopiskelijoiden käsityksiä neurologisesta fysioterapiasta. Terveystieteiden laitos, Jyväskylän yliopisto, (fysioterapia) pro gradu -tutkielma. 49 s., 9 liitettä. Tutkimuksen tarkoituksena oli ymmärtää valmistuvien fysioterapeuttien käsityksiä neurologisesta fysioterapiasta ja sen oppimisesta. Ymmärtämällä opiskelijoiden käsityksiä tutkittavasta ilmiöstä voidaan kehittää opetussuunnitelmaa opiskelijalähtöisesti. Neurologiset potilaat ovat olleet vuosikymmenien ajan yksi keskeisimmistä fysioterapiaa saaneista asiakasryhmistä ja väestön ikääntyessä neurologisia sairauksia sairastavien määrä lisääntyy edelleen. Neurologisen fysioterapi…

Griscelli-Syndrom: ein Fallbericht

2003

Background: Griscelli syndrome is a rare disorder with poor prognosis. It is characterized by silver-grey hair or strands of silver-grey hair in childhood, and variable cellular immunodeficiency. The course of the untreated disease is fatal. Recurrent episodes of fever and lymphohistocytic infiltration of organs lead to hepatosplenomegaly, lymphadenopathy, pancytopenia, and progressive neurological impairment. Prognosis on morbidity and lethality depends on an early diagnosis. Patient: The girl we report on suffers from Griscelli syndrome. She developed normally and only her grey strands of hair, grey eyebrows, and eyelids were conspicuous. With the age of 4 years she presented with a first…

Papel de la eminencia talámica, el sistema olfativo principal y el sistema olfativo accesorio en la maduración sexual del encéfalo y las manifestacio…

2014

El desarrollo de sistema olfativo y la diferenciación sexual del encéfalo, tanto en el hombre como en los animales, están estrechamente relacionados. Actualmente, se describe la imbricación entre la formación del sistema olfativo principal y la migración de las neuronas que sintetizan la hormona liberadora de gonadotrofinas (GnRF). Estas neuronas GnRF se desplazan por los nervios olfatorios, desde la parte medial del epitelio nasal al bulbo olfatorio, continúan por el encéfalo rostral hasta alcanzar el hipotálamo anterior. Por otro lado, el síndrome de Kallmann es un trastorno genético en el cual se combina el hipogonadismo hipogonadotrópico y la anosmia. El hipogonadismo se caracteriza por…

Food of the Gods for the Treatment of Multiple Sclerosis Related Fatigue?

2019

In their JNNP paper, Coe et al report the preliminary results of a feasibility trial on flavonoid enriched cocoa for the treatment of multiple sclerosis (MS) related fatigue, showing promising results that encourage the conduction of a phase III clinical trial to confirm the results of possible clinical effects on MS related fatigue.1 As described in the paper,1 fatigue is the most common symptom reported by individuals affected by MS, affecting the majority of patients. It is often present even when neurological disability is low and in the early stages of the disease, but impacts significantly the quality of life in MS patients, diminishing independence in everyday activities. Fatigue sym…