Search results for "Neurology"
showing 10 items of 11123 documents
Author response: Septin/anillin filaments scaffold central nervous system myelin to accelerate nerve conduction
2016
Le jugement d’oubli dans la maladie d’Alzheimer
2017
International audience; IntroductionAvez-vous déjà eu l’impression d’oublier quelque chose ? Le sentiment d’oubli est très commun dans la vie quotidienne mais a été très peu étudié expérimentalement.ObjectifsL’objectif de cette étude est d’évaluer les jugements d’oubli sur des tâches de mémoire sémantique et épisodique dans le vieillissement normal et dans la maladie d’Alzheimer.Patients et méthodesCinquante jeunes adultes, 35 personnes âgées et 33 patients Alzheimer ont été testés. Les participants effectuaient soit des jugements d’oubli, soit des jugements de rappel sur 2 tâches de mémoire. Pour la tâche de mémoire sémantique, les participants devaient rappeler toutes les régions de Franc…
Breathing and its stimulatory responses in parkinsonism: repercussions for physiotherapy
2020
This study addresses respiratory and motor impairments in an experimental reserpine-induced model of parkinsonism in rats. The role of chronic hypoxia due to diminished ventilation in the development and course of neurodegeneration is addressed. An attempt was made to distinguish between central and peripheral dopamine pathways in the mechanisms of neurodegeneration. A dissociation of putative mechanisms of respiratory and motor impairments is tackled as well. Although this purely experimental study cannot be directly extrapolated to human pathophysiology, the corollaries have been drawn concerning the potential repercussions of the respiratory and motor impairments for the physiotherapeuti…
Hypotensive eyedrops: The neverending story. Should we consider more than active principles?
2017
Subarachnoid Haemorrhage in an Elderly Patient with Comorbidities
2020
Abstract Subdural hemorrhage is usually caused by a traumatic injury. Other risk factors that may lead to subdural hemorrhage include: hypertension, anticoagulants, elderly, alcohol abuse, vascular abnormalities etc. Mortality range is between 50% and 90% depending on age, admission Glasgow Coma Scale (GCS) and anticoagulant treatment. We present a case of 74-year old patient, female, known for diabetes, high blood pressure, obesity, chronic heart failure, receiving anticoagulant treatment, bronchial asthma who develops a posttraumatic massive chronic subdural hematoma accompanied by comorbidities.
Prognostic value of Hutchinson's sign for ocular involvement in herpes zoster ophthalmicus
2017
Management of chronic knee osteoarthritis pain: Where are we going?
2016
Recent Advances in Computational Approaches for Designing Potential Anti-Alzheimer’s Agents
2017
“Brainstorming”: Extracellular Vesicles in Physical Activity and Neuronal Health
2020
Physical and mental activity are known to contribute to brain health and overall longevity. Extracellular vesicles (EVs) have attracted attention for their ability to transport bioactive cargo through various body-fluids and their role in tissue crosstalk and regeneration. Targeted intercellular communication processes, including those facilitated by EVs, are of vital importance for the complex architecture and function of the brain. Activated neurons trigger the transfer of EVs from myelinating oligodendrocytes to neurons, promoting neuronal long-term maintenance and survival. Likewise, physical activity leads to the liberation of EVs into the circulation, while the molecular link between …
Patología vascular: ¿causa o efecto en la enfermedad de Alzheimer?
2018
Resumen: Introducción: La enfermedad de Alzheimer (EA) es la principal enfermedad neurodegenerativa cortical. Su incidencia aumenta con la edad, lo que provoca importantes problemas médicos, sociales y económicos, especialmente en países con población envejecida. Objetivo: El objetivo de esta revisión es poner de manifiesto las evidencias que existen sobre el modo en que la disfunción vascular puede contribuir al deterioro cognitivo en la EA, así como las posibilidades terapéuticas que de ello podrían derivarse. Desarrollo: La hipótesis vascular ha surgido como alternativa a la hipótesis de la cascada amiloide como explicación de la fisiopatología de la EA. Esta hipótesis sitúa en los vasos…