Search results for "Nevus"
showing 10 items of 64 documents
Nevus epidérmico verrugoso unilateral
2007
Seguimiento digitalizado combinado en población con alto riesgo de desarrollar un melanoma maligno: análisis retrospectivo de 152 pacientes
2021
Resumen: Antecedentes: La dermatoscopia digitalizada (DD) ha demostrado mejorar la precisión en el diagnóstico del melanoma (MM) en pacientes de alto riesgo. La combinación de DD y fotografía corporal total (FCT) puede facilitar la detección de nuevas lesiones o la aparición de cambios macroscópicos precoces en lesiones previamente registradas. Objetivos: El objetivo del presente estudio fue determinar el número de biopsias necesarias para diagnosticar un MM y, las características clínicas y dermatoscópicas asociadas al diagnóstico de melanoma en pacientes en seguimiento, mediante DD y FCT, de lesiones pigmentadas. Pacientes y métodos: Se realizó un estudio retrospectivo de 152 pacientes co…
Über das Vorkommen von „Hämatoxylin-Körpern” bei einem Naevuszellnaevus und einer Melanosis Dubreuilh
1966
Typischen „Hamatoxylin-Korperchen” (Gross), wie sie als Suchzeichen zur autoptischen Erfassung eines Lupus erythematodes bekannt sind, im HE-Schnitt auserst ahnliche, wenn nicht gar identische „Karyolyten” werden im Epidermis-nahen Cutisbereich eines Naevuszellnaevus vom Compound-Typ sowie einer Melanosis praeblastomatosa circumscripta Dubreuilh beschrieben. Die Genese derartiger Gebilde (physiko-chemische Zustandsanderungen in Nahe der Basalzell-Linie vielleicht infolge Durchtrankung mit Blutplasmaeiweisstoffen von antinuclearem Charakter) wird erortert. Dabei wird die Frage, ob dem Vorkommen solcher „Hamatoxylin-Korperchen”, wie sie vorangehend auch schon bei anderen Krankheitszustanden a…
Progressive depigmentation of a melanocytic lesion: a dermoscopic challenge for melanoma diagnosis.
2013
Sex and MC1R variants in human pigmentation: Differences in tanning ability and sensitivity to sunlight between sexes
2016
Expression of the Tumor Suppressor Gene Product p16INK4 in Benign and Malignant Melanocytic Lesions
1998
The gene MTS1 encodes p16INK4, an inhibitor of cyclin-dependent kinase 4, and is frequently deleted, mutated, or silenced by promoter methylation in melanoma cells and in the germline of familial melanoma patients. Although MTS1 may thus be the candidate melanoma suppressor gene that maps to chromosome 9p21, it is not clear how dysfunction at that locus temporally relates to melanoma progression. To further test its role in sporadic melanoma, the expression of p16INK4-protein and -mRNA was characterized in melanomas and melanocytic nevi by immunocytochemistry and in situ reverse transcriptase-polymerase chain reaction. Histologic tissue sections were immunolabeled with anti-p16INK4 antibody…
BRAF V600E Mutation in Two Distinct Meningeal Melanocytomas Associated With a Nevus of Ota
2014
Freestyle-Like V-Y Flaps of the Eyebrow: A New Outlook and Indication of an Historical Technique
2013
The eyebrow region is of utmost importance for facial movement, symmetry, and the overall cosmetic appearance of the face. Trauma or tumor resection often leave scars that may dislocate the eyebrow producing an alteration both in static symmetry of the face and in the dynamic expressivity. The authors present a technique for eyebrow’s defects repair using the remaining eyebrow advancement by means of a “freestyle-like” V-Y flap. In the past two years a total of eight consecutive patients underwent excision of skin lesions in the superciliary region and immediate reconstruction with this technique. On histology, six patients were affected from basal cell carcinomas, one from squamous cell ca…
The recurrence of odontogenic keratocysts in pediatric patients is associated with clinical findings of Gorlin-Goltz Syndrome
2019
Background Odontogenic keratocyst (OKC) is an odontogenic developmental cyst that presents distinct clinical behavior. This lesion has been described as dental cysts with keratinization since the 1930s, however the term "OKC" was established in 1956. This study aims to determine the frequency and features of OKC in children aged 0 to 14 years in an oral pathology service in Brazil. Material and Methods A retrospective study was performed to review cases of OKC in children diagnosed between 1986 and 2017. Clinical data were evaluated from medical records (gender, race, age, anatomical location, treatment, radiographic findings and follow-up). Results Ninety-seven cases of OKC were diagnosed …
Oculoectodermal syndrome: Report of a new case with a broad clinical spectrum
2014
Oculoectodermal syndrome (OMIM 600268) is rare and characterized by aplasia cutis congenita, epibulbar dermoids, and other abnormalities. We report herein on a newly recognized patient with oculoectodermal syndrome, which is the 19th reported patient with OES. The boy aged six years demonstrated a broad clinical spectrum of this condition, including aplasia cutis congenita, epibulbar dermoids, hyperkeratotic papule, mildly enlarged cisterna magna, and an enlarged fluid space in the quadrigeminal cistern, suggesting a cyst. He also manifested anomalies not reported associated with this disorder, including systematized epidermal nevus following Blaschko's lines, hypopigmented skin lesions, an…