Search results for "Node"
showing 10 items of 1701 documents
Electrochemical reduction of carbon dioxide to formic acid at a tin cathode in divided and undivided cells: effect of carbon dioxide pressure and oth…
2016
Abstract The reduction of carbon dioxide to formic acid at a tin cathode was studied in both divided and undivided cells. In the first stage of the study, the effect of some operating parameters, including the working potential and the nature of the supporting electrolyte and of the cathode, on both the cathodic reduction of CO2 and the anodic oxidation of formic acid was investigated in a divided cell. In a second stage, the reduction of carbon dioxide was performed in an undivided cell with the aim of studying the effect on the generation of formic acid of various operating parameters such as current density, cathode to anode area ratio, mixing rate and nature of the anode and of the supp…
Mechanism of Sinoatrial Node Dysfunction in a RyR 2 R420Q Mouse Model Ofcatecholaminergic Polymorphic Ventricular Tachycardia
2017
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a genetic disease characterized by stress-induced syncope and/or sudden death in young individuals with structurally normal heart. More than 150 mutations located in the cardiac Ca2+ release channel (type-2 ryanodine receptor, RyR2) gene are related to CPVT. Besides ventricular tachycardia (VT) under stress, sinoatrial node (SAN) dysfunction is frequently observed in CPVT patients. However, the cellular mechanisms remain underexplored. We created a KI mice model bearing a mutation in the N-terminal portion of the RyR2 found in a CPVT family, RyR2(R420Q). ECGs were recorded in KI and WT littermates in resting condition and after…
The Use of a Surgical Patch in the Prevention of Lymphoceles After Extraperitoneal Pelvic Lymphadenectomy for Prostate Cancer: A Randomized Prospecti…
2009
Purpose: Pelvic lymphadenectomy is frequently performed simultaneously with radical prostatectomy to determine lymph node status and the most frequently recorded postoperative complication is the development of a symptomatic lymphocele. This study evaluated TachoSil® as an adjunct treatment in preventing lymphoceles after extraperitoneal pelvic lymphadenectomy for prostate cancer. Materials and Methods: A total of 60 consecutive patients who had undergone radical prostatectomy and pelvic lymphadenectomy were prospectively enrolled in this study. The patients were randomly assigned to a standard technique with the use of clips and electrocoagulation plus TachoSil, or to standard technique on…
Intrahepatic cholangiocarcinoma: Limitations for resectability, current surgical concepts and future perspectives.
2020
Intrahepatic cholangiocarcinoma (iCCA) is the second most common hepatic malignancy and its incidence has been shown to increase significantly during the past decades. Complete surgical resection is currently acknowledged as the only curative treatment option able to provide adequate long-term outcomes. We herein review technical, functional and oncologic limitations for resectability, discuss current surgical aspects as well as highlight the fields in which future research and practice should focus on in order to ameliorate long-term outcomes in patients with iCCA.
Morphometry and comparative histology of sinus and atrioventricular nodes in humans and pigs and their relevance in the prevention of nodal arrhythmi…
2019
The cardiac conduction system is a network structure that allows the initiation and fast propagation of electrical impulses that trigger the electrical depolarization of the myocardial tissue. The purpose of this work is to study the histological and morphometric characteristics of the different components of the sinus and atrioventricular nodes in humans and pigs and their relationship with supraventricular arrhythmias. In this study, we describe the morphometry of the sinus and atrioventricular nodes of 10 adult humans and 10 pig hearts. A computerized morphometric study has been carried out, where we determined the number of cells that compose the nodes as well as different parameters re…
Are homalozoans echinoderms? An answer from the extraxial-axial theory
2000
Homalozoans include four classes of non-pentamerous Paleozoic echinoderms: Homostelea (cinctans), Ctenocystoidea (ctenoid-bearing homalozoans), Homoiostelea (solutes), and Stylophora (cornutes and mitrates). Their atypical morphologies have historically made it difficult to relate them to other classes. Therefore, their systematic positions have been represented by two hypotheses (H): as stem taxa to echinoderms (H1) or as stem taxa to chordates (H2). These conclusions rest on previous inability to recognize synapomorphies with more crownward echinoderms, resulting in a forcing of the homalozoans down the phylogenetic tree that is more artifactual than evolutionary. The Extraxial-Axial Theo…
New specimens of Lingulocystis Thoral, 1935 (Eocrinoidea, Blastozoa) from the Arenig (Lower Ordovician) of Montagne noire (southern France): Intraspe…
2007
16 pages; The genus Lingulocystis Thoral, 1935 is a preponderant component of the echinoderm fauna of the Lower Ordovician of Montagne noire (France), as suggested by its abundant remains. Its morphology is characterized by a flattened theca, composed of a frame enclosing numerous small polygonal central plates. The new specimens have been determined partly as Lingulocystis elongata Thoral, 1935 and partly as Lingulocystis aff. deani Ubaghs, 1994. This study is the first report of Lingulocystis in the Foulon Formation. New stratigraphic ranges have been defined for both species: L. elongata from the early Tremadoc (Saint- Chinian Formation) to the middle Arenig (lower part of the Landeyran …
Description of two new fossil echinoids (Echinodermata: Echinoidea) from the Early Hauterivian (Early Cretaceous) of the Paris Basin (France)
2012
International audience; Deux nouveaux genres et espèces d'échinides, Salvaster roberti gen. et sp. nov. et Pygolampas edita gen. et sp. nov. provenant de la Formation des Calcaires à Spatangues (CSF) sont décrits. La CSF correspond à des sédiments calcaréo-argileux déposés dans le sud-est du bassin de Paris (France) à l'Hauterivien inférieur (Crétacé inférieur). Ces dépôts sont datés de la chronozone à Acanthodiscus radiatus, un intervalle de temps qui a correspondu à un haut niveau marin général en Europe de l'Ouest. La CSF a pourtant livré une riche faune fossile d'environnement marin peu profond, principalement représentée par des invertébrés benthiques. Parmi ceux-ci, 54 espèces d'échin…
Long Daytime Napping Is Associated with Increased Adiposity and Type 2 Diabetes in an Elderly Population with Metabolic Syndrome.
2019
The authors especially thank the PREDIMED-Plus participants for their enthusiastic collaboration, the PREDIMED-Plus personnel for their outstanding support, and the personnel of all associated primary care centers for their exceptional effort. Centros de Investigación Biomédica en Red: Obesidad y Nutrición (CIBEROBN), Centros de Investigación Biomédica en Red: Epidemiología y Salud Pública (CIBERESP) and Centros de Investigación Biomédica en Red: Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM) are initiatives of Instituto de Salud Carlos III (ISCIII), Madrid, Spain. We thank the PREDIMED-Plus Biobank Network, part of the National Biobank Platform of ISCIII for storing and managing …
Active suppression induced by cutaneous exposure to bacterial superantigen is prevented by interleukin-12 treatmentin vivo
1998
Exposure to the bacterial superantigen staphylococcal enterotoxin B (SEB) leads to inhibition of several immune responses and the induction of regulatory cells. The aim of this study was to characterize these regulatory cells further and to investigate the effect of interleukin-12 (IL-12) on superantigen-induced suppression. For this purpose BALB/c mice were injected subcutaneously with low doses of SEB that did not deplete the SEB-reactive V beta T cells. Intravenous transfer of unseparated local-draining lymph node cells from these SEB-treated animals suppressed the proliferative response of mononuclear spleen cells of naive syngeneic recipients for at least 3 weeks. The regulatory cells …