Search results for "Normal"

showing 10 items of 2571 documents

Investigation of the maxillary lateral incisor agenesis and associated dental anomalies in an orthodontic patient population

2011

CEYLAN, Ismail/0000-0002-8693-4175; KAMAK, HASAN/0000-0003-1910-3694 WOS: 000314401800025 PubMed: 22549676 Objectives: The aim of this study was to investigate the prevalence of maxillary lateral incisor (MLI) agenesis and associated dental anomalies as well as skeletal patterns in an orthodontic population, and then to compare it with the prevalence of these anomalies in the general population. Study Design: The material of the present study included the records of the 3872 orthodontic patients. The followings were recorded for each subject with the agenesis of MLI: Age, sex, unilateral or bilateral absence, anterior-posterior skeletal relationship of the maxilla and mandible, and presence…

AdultMaleMaxillary lateral incisor agenesisAdolescentmissing lateralsPopulationDentistryOrthodonticsOdontologíaYoung AdultIncisorClinical and Experimental DentistrymedicineMaxillaPrevalenceHumansAbnormalities MultipleeducationChildGeneral DentistryMaxillary lateral incisoreducation.field_of_studybusiness.industryTooth AbnormalitiesHypodontiaMaxillary caninemedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludIncisorstomatognathic diseasesmedicine.anatomical_structureOtorhinolaryngologyassociated dental anomaliesAgenesisMaxillaUNESCO::CIENCIAS MÉDICASSurgeryFemaleResearch-ArticleMalocclusionbusinessMalocclusion
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Assessment of brainstem function in Chiari II malformation utilizing brainstem auditory evoked potentials (BAEP), blink reflex and masseter reflex

2000

Brainstem dysfunction was evaluated in 67 patients with myelomeningocele and Chiari II malformation using brainstem auditory evoked potentials (BAEP), blink reflex (BR) and masseter reflex (MR). Signs and symptoms related to Chiari II malformation were observed in 18 patients while 49 patients had normal brainstem findings. BAEP and BR showed a higher sensitivity of brainstem involvement than MR (BAEP=1.0, BR=0.83, MR=0.50). BR, and in particular, MR were of higher accuracy (BR=0.52, MR=0.72) than BAEP (0.39) in separating patients with brainstem signs and symptoms related to Chiari II malformation. We feel that this is due to anatomic and physiologic peculiarities of the brainstem structur…

AdultMaleMeningomyeloceleAdolescentgenetic structuresCentral nervous systemSigns and symptomsSensitivity and SpecificityCentral nervous system diseaseDevelopmental NeuroscienceReflexEvoked Potentials Auditory Brain Stemotorhinolaryngologic diseasesmedicineHumansCorneal reflexChildBlinkingMasseter Musclebusiness.industryGeneral Medicinemedicine.diseaseArnold-Chiari Malformationmedicine.anatomical_structureChild PreschoolAnesthesiaPediatrics Perinatology and Child HealthReflexFemaleNeurology (clinical)BrainstembusinessJaw jerk reflexNormal brainstemBrain StemHydrocephalusBrain and Development
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Israeli Spotted Fever in Sicily. Description of two cases and minireview

2017

Mediterranean spotted fever (MSF) is endemic in Italy, where Rickettsia conorii subsp. conorii was thought to be the only pathogenic rickettsia and Rhipicephalus sanguineus the vector and main reservoir. R. conorii subsp. israelensis, which belongs to the R. conorii complex, is the agent of Israeli spotted fever (ISF); apart from Israel, it has also been found in Italy (Sicily and Sardinia) and in different regions of Portugal. We describe here two severe cases of ISF which occurred in otherwise healthy Italian adults. Their characteristics are analyzed and discussed in the light of other 91 cases found through a systematic review of international literature.

AdultMaleMicrobiology (medical)Settore MED/17 - Malattie InfettiveIsraeli spotted fever; Mediterranean spotted fever; Rickettsia israelensis; Microbiology (medical); Infectious DiseasesRhipicephalus sanguineus030231 tropical medicineBoutonneuse Feverlcsh:Infectious and parasitic diseases03 medical and health sciences0302 clinical medicinemedicineInternational literatureAnimalsHumanslcsh:RC109-216Rickettsia israelensi030212 general & internal medicineIsraelSicilyNormal rangebiologyMediterranean spotted feverGeneral Medicinebiology.organism_classificationmedicine.diseaseIsraeli spotted feverVirologySpotted feverBoutonneuse feverRickettsia conoriiInfectious DiseasesRickettsiaRickettsia israelensisVector (epidemiology)FemaleRickettsia conoriiInternational Journal of Infectious Diseases
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New syndrome: Autosomal dominant microcephaly and radio-ulnar synostosis

1994

To date, the combination of microcephaly and radio-ulnar synostosis has not been recognized as a distinct clinical and genetic entity. We report on 4 familial cases with this previously undescribed combination of defects, showing autosomal dominant inheritance (Fig. 1). © 1994 Wiley-Liss, Inc.

AdultMaleMicrocephalyAdolescentUlnaSupinationMedicineHumansAbnormalities MultiplemicrocephalyChildGenetics (clinical)Genes Dominantradioulnar synostosisbusiness.industryfungiInfantAnatomySyndromeSynostosisMiddle Agedmedicine.diseasePedigreeautosomal dominant inheritanceRadiusSynostosisRadioulnar synostosisFemaleCongenital diseasebusinessHand Deformities Congenital
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A two base pair deletion in the PQBP1 gene is associated with microphthalmia, microcephaly, and mental retardation.

2007

X-linked mental retardation has been traditionally divided into syndromic (S-XLMR) and non-syndromic forms (NS-XLMR), although the borderlines between these phenotypes begin to vanish and mutations in a single gene, for example PQBP1, can cause S-XLMR as well as NS-XLMR. Here, we report two maternal cousins with an apparently X-linked phenotype of mental retardation (MR), microphthalmia, choroid coloboma, microcephaly, renal hypoplasia, and spastic paraplegia. By multipoint linkage analysis with markers spanning the entire X-chromosome we mapped the disease locus to a 28-Mb interval between Xp11.4 and Xq12, including the BCOR gene. A missense mutation in BCOR was described in a family with …

AdultMaleMicrocephalycongenital hereditary and neonatal diseases and abnormalitiesGermline mosaicismLocus (genetics)BiologyMicrophthalmiaFrameshift mutationGenetic linkageGenes X-LinkedIntellectual DisabilityGeneticsmedicineMissense mutationHumansMicrophthalmosAbnormalities MultipleFrameshift MutationGenetics (clinical)GeneticsChromosomes Human XNuclear ProteinsGenetic Diseases X-LinkedSyndromemedicine.diseasePedigreeLenz microphthalmia syndromeDNA-Binding ProteinsChild PreschoolMicrocephalyFemaleCarrier ProteinsGene DeletionEuropean journal of human genetics : EJHG
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Hereditary motor sensory neuropathy type II with neurofilament accumulation: new finding or new disorder?

1985

Peroneal muscular atrophy is now known to be heterogeneous and to be due to various underlying genetic mechanisms. Exploring this heterogeneity further, we report on a German kinship with the clinical, genetic, and nerve conduction features of hereditary motor and sensory neuropathy type II (HMSN type II) but whose sural nerves on biopsy were found to show infrequent axonal swellings with neurofilament accumulations not previously described. The dominant inheritance and absence of kinky hair set this disorder apart from giant axonal neuropathy. There was no history of toxic exposure to industrial chemicals. We conclude that the disorder either is a new type of HMSN or is HMSN type II with p…

AdultMaleNeurofilamentAdolescentBiopsyCardiomyopathyNeural ConductionCardiovascular System03 medical and health sciences0302 clinical medicineSural NerveEvoked Potentials SomatosensoryBiopsymedicineHumansAxonHereditary Sensory and Autonomic NeuropathiesChildCytoskeleton030304 developmental biologyGiant axonal neuropathyAged0303 health sciencesmedicine.diagnostic_testbusiness.industryElectromyographyPeroneal muscular atrophyMiddle Agedmedicine.diseaseAxonsPedigreeMicroscopy ElectronMuscular Atrophymedicine.anatomical_structureNeurologyEvoked Potentials VisualFemaleNeurology (clinical)AbnormalityHereditary motor and sensory neuropathybusinessNeuroscience030217 neurology & neurosurgeryAnnals of neurology
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End-plate dysfunction in acute organophosphate intoxication.

1989

Acute organophosphate intoxication resulting from suicide attempts in 14 patients produced a series of electrophysiologic abnormalities that correlated with the clinical course. Spontaneous repetitive firing of single evoked compound muscle action potentials (CMAP) was the earliest and most sensitive indicator of the acetylcholinesterase inhibition. A decrement of evoked CMAP following repetitive nerve stimulation was the most severe abnormality. At the height of the intoxication no CMAP was evoked after the first few stimuli. The decrement-increment phenomenon occurred only at milder stages of intoxication and its features are characteristic of acetylcholinesterase inhibition. These electr…

AdultMaleNeuromuscular JunctionSuicide AttemptedMotor Endplatechemistry.chemical_compoundOrganophosphate PoisoningMuscle actionmedicineCholinesterasesHumansBotulismRepetitive nerve stimulationEvoked Potentialsbusiness.industryMusclesClinical courseMiddle Agedmedicine.diseaseAcetylcholinesteraseRespiration ArtificialMyasthenia gravisElectric StimulationOrganophosphate intoxicationMedian NervechemistryAnesthesiaFemaleNeurology (clinical)AbnormalitybusinessNeurology
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Spatial variability of muscle activity during human walking: The effects of different EMG normalization approaches

2015

Human leg muscles are often activated inhomogeneously, e.g. in standing. This may also occur in complex tasks like walking. Thus, bipolar surface electromyography (sEMG) may not accurately represent whole muscle activity. This study used 64-electrode high-density sEMG (HD-sEMG) to examine spatial variability of lateral gastrocnemius (LG) muscle activity during the stance phase of walking, maximal voluntary contractions (MVCs) and maximal M-waves, and determined the effects of different normalization approaches on spatial and inter-participant variability. Plantar flexion MVC, maximal electrically elicited M-waves and walking at self-selected speed were recorded in eight healthy males aged 2…

AdultMaleNormalization (statistics)EMG normalizationmedicine.medical_specialtyWalkingElectromyographyta3112Young AdultPhysical medicine and rehabilitationmedicineHumansHuman legMuscle activityMultichannel EMGMuscle Skeletalta315MathematicsLegmedicine.diagnostic_testElectromyographyGeneral NeuroscienceReproducibility of ResultsSignal Processing Computer-AssistedElectric StimulationElectromyogramData Interpretation StatisticalGait analysisPhysical therapySpatial variabilityGait analysisPeak valuehuman activitiesLateral gastrocnemiusNEUROSCIENCE
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Dual-Energy CT Material Density Iodine Quantification for Distinguishing Vascular From Nonvascular Renal Lesions: Normalization Reduces Intermanufact…

2019

OBJECTIVE. The purpose of this study was to determine whether a single, uniform normalized iodine threshold reduces variability and enables reliable differentiation between vascular and nonvascular renal lesions independent of the dual-energy CT (DECT) platform used. MATERIALS AND METHODS. In this retrospective, HIPAA-compliant, institutional review board-approved study, 247 patients (156 men, 91 women; mean age ± SD, 67 ± 12 years old) with 263 renal lesions (193 nonvascular, 70 vascular) underwent unenhanced single- energy and contrast-enhanced DECT scans. One hundred and six nonvascular and 38 vascular lesions were scanned on two dual-source DECT (dsDECT) scanners, and 87 nonvascular and…

AdultMaleNormalization (statistics)chemistry.chemical_elementIodinedual-energy CTrapid-kilovoltage switching030218 nuclear medicine & medical imagingDiagnosis DifferentialRadiography Dual-Energy Scanned ProjectionYoung Adult03 medical and health sciences0302 clinical medicineHumansMedicineDual sourceRadiology Nuclear Medicine and imagingAgedRetrospective StudiesAged 80 and overvariabilitybusiness.industryGeneral MedicineMaterial densityMiddle Agedrenal lesionKidney Neoplasmschemistry030220 oncology & carcinogenesisdual sourceFemaleDual energy ctTomography X-Ray ComputedbusinessNuclear medicineIodineAmerican Journal of Roentgenology
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Escalation from normal appearance related intrusive cognitions to clinical preoccupations in Body Dysmorphic Disorder: A cross-sectional study

2018

Abstract Current cognitive approaches to Body Dysmorphic Disorder (BDD) assume that appearance-related intrusive cognitions and their functional consequences characterize the disorder, in a similar way that obsessive intrusive thoughts characterize the Obsessive-Compulsive Disorder (OCD). This study explores whether normal but unwanted appearance-related intrusive thoughts (AITs), escalate to clinical AITs when they are dysfunctionally appraised and instigate counterproductive neutralizing strategies. From a sample of 344 non-clinical individuals who reported a highly upsetting AIT during the past three months two subgroups were extracted according to their high (n = 68) and low (n = 276) v…

AdultMaleObsessive-Compulsive Disorder050103 clinical psychologyAdolescentCross-sectional studyEmotionsThinkingYoung Adult03 medical and health sciencesCognition0302 clinical medicinemental disordersmedicineHumans0501 psychology and cognitive sciencesNormal appearanceBiological PsychiatryCognitive Behavioral Therapy05 social sciencesCognitionBody Dysmorphic Disordersmedicine.diseasePsychiatry and Mental healthCross-Sectional StudiesBody dysmorphic disorderFemalePast Three MonthsPsychology030217 neurology & neurosurgeryClinical psychologyPsychiatry Research
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