Search results for "Normal"

showing 10 items of 2571 documents

Granuloma anulare disseminatum als seltene Nebenwirkung von Allopurinol

1995

During long-term therapy of hyperuricaemia with allopurinol (300 mg/d) two patients developed generalized granuloma annulare. The diagnoses were confirmed by histology; concomitant diseases, especially diabetes mellitus, were not detectable. Following discontinuation of allopurinol therapy, cutaneous granulomas healed without relapse. Hyperuricaemia could be controlled by low-purine diet and medication avoiding allopurinol. The clinical history of our two patients suggested a causal connection between allopurinol therapy and generalized granuloma annulare. For this reason we rate the development of this disease in both cases as a rare but significant side effect of allopurinol. This should …

musculoskeletal diseasescongenital hereditary and neonatal diseases and abnormalitiesmedicine.medical_specialtyChemotherapySide effectbusiness.industrymedicine.medical_treatmentnutritional and metabolic diseasesAllopurinolDermatologymedicine.diseaseConcomitant drugDermatologyDiscontinuationGranulomaConcomitantmedicinebusinessmedicine.drugGeneralized granuloma annulareDer Hautarzt
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Novel Digital Technique to Quantify the Area and Volume of Cement Remaining and Enamel Removed after Fixed Multibracket Appliance Therapy Debonding: …

2020

The aim of this study was to construct a novel, repeatable, reproducible, and accurate measurement protocol for the area and volume of the remaining cement after removal of fixed multibracket appliances, the area and volume of remaining cement after cement removal, the area and volume of enamel removed after cement removal, and the volume of cement used to adhere fixed multibracket appliances. A total of 30 brackets were cemented and removed with over 30 extracted teeth embedded into three experimental models of epoxy resin. The models were scanned before and after bracket placement, bracket debonding, and polishing the remaining cement. The brackets were submitted to micro-computed tomogra…

musculoskeletal diseaseslcsh:MedicineCementos dentales.Orthodontics.Article03 medical and health sciences0302 clinical medicineDientes - Anomalías y malformaciones - Tratamiento.Teeth - Abnormalities - Treatment.Dental cement0502 economics and businessOrtodoncia.In vitro studyMedicineMateriales dentales.Dental therapeutics - Equipment and supplies.CementTerapéutica dental - Aparatos y material.ReproducibilityDental enamel.Enamel paintDental cements.business.industryenamel removedlcsh:R05 social sciencesBrackettechnology industry and agriculturegeomorphometryalignment030206 dentistryGeneral MedicineRepeatabilityequipment and suppliesEsmalte dental.surgical procedures operativecement remainingvisual_artdigital impressionvisual_art.visual_art_medium050211 marketingDental materials.businessorthodonticsBiomedical engineeringVolume (compression)Journal of Clinical Medicine
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Combined effect of AAV-U7-induced dystrophin exon skipping and soluble activin Type IIB receptor in mdx mice.

2012

Adeno-associated virus (AAV)-U7-mediated skipping of dystrophin-exon-23 restores dystrophin expression and muscle function in the mdx mouse model of Duchenne muscular dystrophy. Soluble activin receptor IIB (sActRIIB-Fc) inhibits signaling of myostatin and homologous molecules and increases muscle mass and function of wild-type and mdx mice. We hypothesized that combined treatment with AAV-U7 and sActRIIB-Fc may synergistically improve mdx muscle function. Bioactivity of sActRIIB-Fc on skeletal muscle was first demonstrated in wild-type mice. In mdx mice we show that AAV-U7-mediated dystrophin restoration improved specific muscle force and resistance to eccentric contractions when applied a…

musculoskeletal diseasesmdx mousemedicine.medical_specialtycongenital hereditary and neonatal diseases and abnormalitiesDuchenne muscular dystrophyActivin Receptors Type IIGenetic VectorsMyostatinBiologyDystrophin03 medical and health sciencesMice0302 clinical medicineInternal medicineGeneticsmedicineMyocyteAnimalsMuscular dystrophyMuscle SkeletalMolecular Biology030304 developmental biology0303 health sciencesBody WeightSkeletal muscleExonsGenetic TherapyDependovirusMuscular Dystrophy Animalmedicine.diseasemusculoskeletal system3. Good healthMice Inbred C57BLEndocrinologymedicine.anatomical_structureImmunologybiology.proteinMice Inbred mdxMolecular MedicineITGA7Dystrophin030217 neurology & neurosurgeryMuscle ContractionHuman gene therapy
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Scientific evidence on the usefulness of intraarticular hyaluronic acid injection in the management of temporomandibular dysfunction

2010

Abstract Hyaluronic acid (HA) is found in high concentrations in cartilage and synovial fluid, and is an important component of the extracellular matrixes ? exerting joint lubrication and buffering actions thanks to its viscoelastic properties. The present study examines the scientific evidence found in the current literature on the usefulness of the intraarticular injection of HA in patients with temporomandibular dysfunction. A literature search was made up until May 2008 in the following databases: PubMed / MEDLINE. Of the articles found in the literature, the present review included 18 relevant studies on the application of HA in the temporomandibular joint (TMJ). The quality, level of …

musculoskeletal diseasesmedicine.medical_specialtyHyaluronic acidMEDLINETemporomandibular joint abnormalities.BioinformaticsScientific evidenceInjections Intra-Articularchemistry.chemical_compoundHyaluronic acidTemporomandibular joint abnormalitiesmedicineSynovial fluidHumansMalformacions de l'articulació temporomandibularHyaluronic AcidGeneral Dentistrybusiness.industryCartilageTherapeutic effectEvidence-based medicineTemporomandibular Joint Dysfunction Syndrome:CIENCIAS MÉDICAS [UNESCO]Àcid hialurònicSurgeryTemporomandibular jointmedicine.anatomical_structureOtorhinolaryngologychemistryUNESCO::CIENCIAS MÉDICASSurgerybusiness
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Joint contractures in the absence of inflammation may indicate mucopolysaccharidosis

2009

Abstract Background Undiagnosed patients with the attenuated form of mucopolysaccharidosis (MPS) type I often have joint symptoms in childhood that prompt referral to a rheumatologist. A survey conducted by Genzyme Corporation of 60 European and Canadian rheumatologists and pediatric rheumatologists demonstrated that Bone and joint manifestations are prominent among most patients with MPS disorders. These life-threatening lysosomal storage diseases are caused by deficient activity of specific enzymes involved in the degradation of glycosaminoglycans. Patients with attenuated MPS disease often experience diagnostic delays. Enzyme replacement therapy is now commercially available for MPS I (l…

musculoskeletal diseasesmedicine.medical_specialtyPediatricscongenital hereditary and neonatal diseases and abnormalitieslcsh:Diseases of the musculoskeletal systemIdursulfaseMucopolysaccharidosisDiseaseRheumatologyInternal medicinemedicineImmunology and AllergyPediatrics Perinatology and Child HealthYoung adultCarpal tunnel syndromeskin and connective tissue diseasesbusiness.industrylcsh:RJ1-570nutritional and metabolic diseaseslcsh:PediatricsEnzyme replacement therapyHypothesismedicine.diseaseRheumatologyJoint painPediatrics Perinatology and Child Healthmedicine.symptomlcsh:RC925-935businessmedicine.drugPediatric Rheumatology
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Dyskeratosis congenita: Report of a case with literature review

2007

Leukoplakic lesion is not uncommon in clinical practice but its occurrence as a component of a syndrome is rare. Dyskeratosis congenita is a rare genodermatosis, which is characterized by triad of skin pigmentation, nail dystrophy and leukoplakic lesion in the oral cavity. It is important for dentists to now about Dyskeratosis Congenita because these leukoplakic lesions can spontaneously undergo malignant transformation. Majority of cases have been reported in dermatology or pediatrics literature whereas only few reports have appeared in dental literature. The purpose of reporting this case with review of recent literature is to create better awareness among dentists about the multisystem m…

nail dystrohpyleukoplakiaUNESCO::CIENCIAS MÉDICASskin pigmentationhematological abnormalities:CIENCIAS MÉDICAS [UNESCO]Dyskeratosis congenita
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Jeg følte meg velkommen : kan ungdommers deltakelse på KickOff – leir påvirke deres utvikling, og i så fall hvordan?

2016

Masteroppgave psykisk helsearbeid - Universitetet i Agder 2016 Background: In The child and youth mental health department (ABUP), is the focus placed on the development of effective interventions. KickOff-camp for youth is an initiative in development. Purpose and research question: The study has a hermeneutic-phenomenological approach, and the intention was to explore adolescent experiences by attending camp. Which experiences can youngsters who have attended KickOff- camp tell about, how come they expressed at the camp, and in what ways might their experiences at camp affect the normal development? Method: The method used for data collection was a qualitative research interview with four…

narrativeutviklingspsykologihermeneutical-phenomenologicalME504developmental psychologysocial constructivismnarrativVDP::Medical disciplines: 700::Health sciences: 800normal developmentnormalutviklinghermeneutisk-fenomenologisksosialkonstruktivistisk
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Natural Addition of Ordinals

2019

Summary In [3] the existence of the Cantor normal form of ordinals was proven in the Mizar system [6]. In this article its uniqueness is proven and then used to formalize the natural sum of ordinals.

natural sumApplied Mathematicshessenberg sumcantor normal form68t99ordinal numbersAlgebraMathematics::LogicComputational Mathematics03e1003b35QA1-939Natural (music)MathematicsMathematicsFormalized Mathematics
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Identification and quantification of phosphatidylcholines containing very long chain polyunsaturated fatty acid (VLC-PUFA) in bovine and human retina…

2010

The retina is one of the vertebrate tissues with the highest content in polyunsaturated fatty acids (PUFA). A large proportion of the retinal glycerophospholipids, especially those found in photoreceptor membranes, are dipolyunsaturated molecular species. Among them, dipolyunsaturated phosphatidylcholine molecular species are known to contain very long chain polyunsaturated fatty acids (VLC-PUFA) from the n-3 and n-6 series and having 24 to 36 carbon atoms (C24 to C36) and four to six double bonds. Recent interest in the role of VLC-PUFA arose from the findings that a protein named ELOngation of Very Long chain fatty acids 4 (ELOVL4) is involved in their biosynthesis and that mutations in E…

normal phase chromatographyhplc chromatographyretinacoupled methodcomplex lipidvertebrataadsorption chromatography[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologytandem mass spectrometryqualitative analysisanimalhumanungulataphosphatidylcholinephospholipid[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologylong chainquantitative analysisbovinepolyunsaturated fatty acideyeeye diseasesanalysis methodartiodactylalipids (amino acids peptides and proteins)mammaliaelectrospray[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Kontrole pār ķermeni: nevakcinēto bērnu piemērs

2018

Bakalaura darbā „Kontrole pār bērna ķermeni: nevakcinēto bērnu piemērs” tiek parādīts, kā notiek zināšanu un informācijas aprite to cilvēku vidē, kuri izvēlas savus bērnus nevakcinēt. Šis darbs ir izstrādāts, analizējot galvenokārt vakcinācijas kontroli, kā arī apskatot normalitātes un soda konceptus, izmantojot medicīnas antropoloģijas teorētisko perspektīvu. Tiek pētīti priekšstati par to, kā vecāku vakcinācijas izvēle tiek kontrolēta, kāpēc un kā bērna nevakcinācija atstāj ietekmi uz vecāku ikdienas praksēm. Apskatīts arī tas, kā nevakcinācija mainījusi viņu priekšstatus par bērna ķermenisko pašizjūtu un kā vecāki izjūt savu bērnu ķermeni pēc izvēlēšanās bērnu nevakcinēt. Bakalaura darbs…

normalitāteAntropoloģijakontrolevakcinācijasankcijasķermenis
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