Search results for "Normal"

showing 10 items of 2571 documents

Novel threat-based AI strategies that incorporate adaptive data structures for multi-player board games

2016

This paper considers the problem of designing novel techniques for multi-player game playing, in a range of board games and configurations. Compared to the well-known case of two-player game playing, multi-player game playing is a more complex problem with unique requirements. To address the unique challenges of this domain, we examine the potential of employing techniques inspired by Adaptive Data Structures (ADSs) to rank opponents based on their relative threats, and using this information to achieve gains in move ordering and tree pruning. We name our new technique the Threat-ADS heuristic. We examine the Threat-ADS’ performance within a range of game models, employing a number of diffe…

Game mechanicsNon-cooperative gameSequential gamebusiness.industryComputer scienceNormal-form gameComputingMilieux_PERSONALCOMPUTINGCombinatorial game theory020207 software engineeringScreening game02 engineering and technologyExtensive-form gameWin-win gameGame designArtificial IntelligenceSimulations and games in economics education0202 electrical engineering electronic engineering information engineeringRepeated game020201 artificial intelligence & image processingArtificial intelligencebusinessGame treeMetagamingApplied Intelligence
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Search for Neutrino‐induced Cascades from Gamma‐Ray Bursts with AMANDA

2007

Using the neutrino telescope AMANDA-II, we have conducted two analyses searching for neutrino-induced cascades from gamma-ray bursts. No evidence of astrophysical neutrinos was found, and limits are presented for several models. We also present neutrino effective areas which allow the calculation of limits for any neutrino production model. The first analysis looked for a statistical excess of events within a sliding window of 1 or 100 seconds (for short and long burst classes, respectively) during the years 2001-2003. The resulting upper limit on the diffuse flux normalization times E^2 for the Waxman-Bahcall model at 1 PeV is 1.6 x 10^-6 GeV cm^-2 s^-1 sr^-1 (a factor of 120 above the the…

Gamma rays: burstsNormalization (statistics)PhysicsRange (particle radiation)MuonAstrophysics::High Energy Astrophysical PhenomenaGamma rays: bursts; Neutrinos; TelescopesAstrophysics (astro-ph)FOS: Physical sciencesAstronomy and AstrophysicsAstrophysicsAstrophysicsCoincidenceSpace and Planetary ScienceCascadeAstronomiaDiffuse fluxHigh Energy Physics::ExperimentNeutrinosNeutrinoGamma-ray burstTelescopesThe Astrophysical Journal
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WT1 isoform expression pattern in acute myeloid leukemia.

2013

WT1 plays a dual role in leukemia development, probably due to an imbalance in the expression of the 4 main WT1 isoforms. We quantify their expression and evaluate them in a series of AML patients. Our data showed a predominant expression of isoform D in AML, although in a lower quantity than in normal CD34+ cells. We found a positive correlation between the total WT1 expression and A, B and C isoforms. The overexpression of WT1 in AML might be due to a relative increase in A, B and C isoforms, together with a relative decrease in isoform D expression.

Gene isoformAdultMalecongenital hereditary and neonatal diseases and abnormalitiesCancer ResearchAdolescentCD34HL-60 CellsBiologyurologic and male genital diseasesPositive correlationCohort StudiesYoung AdultDual roleExpression patternhemic and lymphatic diseasesmedicineTumor Cells CulturedHumansProtein IsoformsWT1 ProteinsAgedAged 80 and overurogenital systemGene Expression Regulation LeukemicGene Expression ProfilingMyeloid leukemiaHematologyMiddle Agedmedicine.diseaseMolecular biologyfemale genital diseases and pregnancy complicationsLeukemiaLeukemia Myeloid AcuteOncologyCase-Control StudiesFemaleK562 CellsLeukemia research
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Relative risk estimation of dengue disease at small spatial scale

2017

Abstract Background Dengue is a high incidence arboviral disease in tropical countries around the world. Colombia is an endemic country due to the favourable environmental conditions for vector survival and spread. Dengue surveillance in Colombia is based in passive notification of cases, supporting monitoring, prediction, risk factor identification and intervention measures. Even though the surveillance network works adequately, disease mapping techniques currently developed and employed for many health problems are not widely applied. We select the Colombian city of Bucaramanga to apply Bayesian areal disease mapping models, testing the challenges and difficulties of the approach. Methods…

General Computer ScienceOperations research030231 tropical medicinePopulationGeographic MappingColombialcsh:Computer applications to medicine. Medical informaticsNormalized Difference Vegetation IndexDengue feverDengue03 medical and health sciencessymbols.namesake0302 clinical medicineCohen's kappaRisk FactorsStatisticsmedicineHumans030212 general & internal medicineSatellite imagesRisk factoreducationEstimationeducation.field_of_studyResearchPublic Health Environmental and Occupational HealthCohen’s KappaMarkov chain Monte CarloBayes Theoremmedicine.diseaseGeneral Business Management and AccountingBayesian modelingGeographyData qualitysymbolsDisease mappinglcsh:R858-859.7International Journal of Health Geographics
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On generalised FC-groups in which normality is a transitive relation

2016

We extend to soluble FC∗ -groups, the class of generalised FC-groups introduced in [F. de Giovanni, A. Russo, G. Vincenzi, Groups with restricted conjugacy classes , Serdica Math. J. 28(3) (2002), 241 254], the characterisation of finite soluble T-groups obtained recently in [G. Kaplan, On T-groups, supersolvable groups and maximal subgroups , Arch. Math. 96 (2011), 19 25].

General Mathematicsmedia_common.quotation_subject0102 computer and information sciencesFC-group01 natural sciencesCombinatoricsT-groupT-groupFC-groupmedia_common.cataloged_instance0101 mathematicsAlgebra over a fieldEuropean unionNormalityMathematicsmedia_commonTransitive relationPronormal subgroup010102 general mathematicsGrups Teoria dePronormal subgroup010201 computation theory & mathematicsT-group FC-group pronormal subgroupÀlgebraMATEMATICA APLICADA
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Communication between mothers and their normal or developmentally dysphasic children in experimental sessions

1991

The interaction of 32 Finnish mother-child dyads were analyzed in order to compare the behavioral features of normally developing (8 boys, 8 girls) and developmentally dysphasic (language-delayed) children (12 boys, 4 girls) doing tasks with their mothers. The average age of the children in the normal group was 4:1 years and in dysphasic group 4:7 years. The groups were matched to educational background of the mothers and to the age of the children. The videotaped observation sessions consisted of a block construction task and a discussion task. Results showed that mothers of dysphasic children tended to be more dominant and controlling and less cooperative. The dysphasic childrens' lower l…

General MedicinePsychologyParent-child communicationNormal groupDevelopmental psychologyScandinavian Journal of Logopedics and Phoniatrics
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Spacetime curvature and Higgs stability after inflation

2015

We investigate the dynamics of the Higgs field at the end of inflation in the minimal scenario consisting of an inflaton field coupled to the Standard Model only through the non-minimal gravitational coupling $\xi$ of the Higgs field. Such a coupling is required by renormalisation of the Standard Model in curved space, and in the current scenario also by vacuum stability during high-scale inflation. We find that for $\xi\gtrsim 1$, rapidly changing spacetime curvature at the end of inflation leads to significant production of Higgs particles, potentially triggering a transition to a negative-energy Planck scale vacuum state and causing an immediate collapse of the Universe.

General PhysicsParticle physicsCosmology and Nongalactic Astrophysics (astro-ph.CO)spacetime curvaturePhysics MultidisciplinaryVacuum stateFOS: Physical sciencesGeneral Physics and Astronomy01 natural sciences09 Engineeringrenormalizationvacuum stateStandard ModelGravitationGeneral Relativity and Quantum CosmologyHigh Energy Physics - Phenomenology (hep-ph)vacuum stability0103 physical sciencesPARTICLE-PRODUCTIONELECTROWEAK VACUUMHiggs fieldHiggs particles010306 general physics01 Mathematical SciencesPlanck scalePhysicsInflation (cosmology)Science & Technology02 Physical SciencesQuantum field theory in curved spacetimeta114010308 nuclear & particles physicsPhysicsHigh Energy Physics::Phenomenologyhep-phInflatonFIELDSThe Standard ModelCREATIONHiggs fieldHigh Energy Physics - PhenomenologyPhysical Sciencesastro-ph.COHiggs bosonAstrophysics - Cosmology and Nongalactic Astrophysics
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FISH of supernumerary marker chromosomes (SMCs) identifies six diagnostically relevant intervals on chromosome 22q and a novel type of bisatellited S…

2005

Supernumerary marker chromosomes (SMCs) are frequently found at pre- and postnatal cytogenetic diagnosis and require identification. A disproportionally large subset of SMCs is derived from the human chromosome 22 and confers tri- or tetrasomy for the cat eye chromosomal region (CECR, the proximal 2 Mb of chromosome 22q) and/or other segments of 22q. Using fluorescence in situ hybridization (FISH) and 15 different DNA probes, we studied nine unrelated patients with an SMC(22) that contained the CECR. Five patients showed the small (type I) cat eye syndrome (CES) chromosome and each one had the larger (type II) CES chromosome, small ring chromosome 22, der(22)t(11;22) extrachromosome, and a …

Genetic MarkersChromosomes Human Pair 22Marker chromosomeRing chromosomeAnal CanalTrisomyBiologyCraniofacial AbnormalitiesGeneticsmedicineHumansAbnormalities MultipleSmall supernumerary marker chromosomeIn Situ Hybridization FluorescenceGenetics (clinical)Chromosome AberrationsGeneticsmedicine.diagnostic_testSyndromemedicine.diseaseMolecular biologyCat eye syndromeColobomaChromosome 17 (human)Chromosome 21Chromosome 22Fluorescence in situ hybridizationEuropean Journal of Human Genetics
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An autosomal dominant retinitis pigmentosa family with close linkage to D7S480 on 7q.

1995

Retinitis pigmentosa is the most prevalent inherited disorder of the retina. It can be autosomal dominant (adRP), autosomal recessive (arRP) or X-linked (XLRP). A form of adRP mapping to chromosome 7q was reported in a large Spanish pedigree. We have typed DNA from the members of another Spanish family for polymorphic markers from the known candidate genes. Positive lod scores were obtained only for the markers located on 7q31-35, giving a maximum lod score of 2.98 (3.01 by multipoint analysis) at theta = 0.00 for D7S480. A brief clinical evaluation is given.

Genetic MarkersMaleCandidate genecongenital hereditary and neonatal diseases and abnormalitiesgenetic structuresBiologyAutosomal dominant retinitis pigmentosaGene mappingRetinitis pigmentosaGeneticsmedicineHumansGeneGenetics (clinical)Genes DominantLinkage (software)GeneticsChromosome Mappingmedicine.diseaseHuman geneticseye diseasesPedigreeGenetic markerFemaleLod ScoreChromosomes Human Pair 7Retinitis PigmentosaHuman genetics
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Comparative architectural aspects of regions of conserved synteny on human chromosome 11p15.3 and mouse chromosome 7 (including genes WEE1 and LMO1)

2001

Human chromosome 11p15.3 is associated with chromosome aberrations in the Beckwith Wiedemann Syndrome and implicated in the pathogenesis of different tumor types including lung cancer and leukemias. To date, only single tumor-relevant genes with linkage to this region (e.g. LMO1) have been found suggesting that this region may harbor additional potential disease associated genes. Although this genomic area has been studied for years, the exact order of genes/chromosome markers between D11S572 and the WEE1 gene locus remained unclear. Using the FISH technique and PAC clones of the flanking markers we determined the order of the genomic markers. Based on these clones we established a PAC cont…

Genetic Markerscongenital hereditary and neonatal diseases and abnormalitiesBeckwith–Wiedemann syndromeCell Cycle ProteinsBiologyChromosomesEvolution MolecularContig MappingMiceChromosome regionsGene OrderMetalloproteinsGeneticsmedicineAnimalsHumansCloning MolecularMolecular BiologyGeneConserved SequenceIn Situ Hybridization FluorescenceGenetics (clinical)Repetitive Sequences Nucleic AcidSyntenyOncogene ProteinsGeneticsChromosome 7 (human)Base CompositionChromosomes Human Pair 11Nuclear ProteinsChromosomeSequence Analysis DNALIM Domain ProteinsProtein-Tyrosine Kinasesmedicine.diseaseAT Rich SequenceGC Rich SequenceDNA-Binding ProteinsChromosome 3CpG IslandsChromosome 21Transcription FactorsCytogenetic and Genome Research
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