Search results for "Normal"

Neuronal intestinal dysplasia

1987

Findings in 23 children with neuronal intestinal dysplasia (NID) are presented. Twelve children had Hirschsprung's disease that masked the existence of proximal NID. In all cases the diagnosis was established by histological-histochemical examination. Amelioration of symptoms by conservative treatment alone was achieved in 4 children; in 13 cases colostomy was necessary. In 6 patients colon resection was performed: 2 suffered from both colitis and obstruction; the other 4 were treated for obstruction, multiple perforations, persistant adynamia of the left colon, and fistulation. In 9 patients the colostomy was closed. Four of 6 children who did not have sonographic confirmation of motility …

Innovations in the Art of Microneurosurgery for Reaching Deep-Seated Cerebral Lesions.

2019

Deep-seated cerebral lesions have fascinated and frustrated countless surgical innovators since the dawn of the microneurosurgical era. To determine the optimal approach, the microneurosurgeon must take into account the characteristics and location of the pathological lesion as well as the operator's range of technical expertise. Increasingly, microneurosurgeons must select between multiple operative corridors that can provide access to the surgical target. Innovative trajectories have emerged for many indications that provide more flexible operative angles and superior exposure but result in longer working distances and more technically demanding maneuvers. In this article, we highlight 4 …

Tear production and intraocular pressure values in clinically normal eyes of whooper swans (<i>Cygnus cygnus</i>)

2018

The objective of this study was to determine the normal range of tear production and values of intraocular pressure (IOP) in clinically normal eyes of whooper swans (Cygnus cygnus). A total of 86 birds: 81 cygnets (6-10 weeks old) and 5 moulting - adult swans (3-6 years old) were examined in this study. Both eyes of all birds underwent a complete ophthalmic examination, including evaluation of tear production with the phenol red thread test (PRTT) and the assessment of the IOP by rebound tonometry, employing the TonoVet® device. The mean ± standard deviation of PRTT values were as follows: all cygnets (81) 22.59±3.48 mm/15s, male cygnets (45) 22.64±3.54 mm/15s, female cygnets (36) 22.53±3.4…

2021

AIM: To investigate short- and long-term intraocular pressure (IOP) fluctuations and further ocular and demographic parameters as predictors for normal tension glaucoma (NTG) progression. METHODS: This retrospective, longitudinal cohort study included 137 eyes of 75 patients with NTG, defined by glaucomatous optic disc or visual field defect with normal IOP (<21 mm Hg), independently from therapy regimen. IOP fluctuation, mean, and maximum were inspected with a mean follow-up of 38mo [standard deviation (SD) 18mo]. Inclusion criteria were the performance of minimum two 48-hour profiles including perimetry, Heidelberg retina tomograph (HRT) imaging, and optic disc photographs. The impact …

Las revistas científico-técnicas españolas de ciencias de la actividad física y el deporte: adecuación a las normas ISO y grado de normalización

2004

Este artículo tiene por objeto conocer el grado de normalización y la adecuación de las revistas científico-técnicas españolas del campo de las Ciencias de la Actividad Física y el Deporte a diversos apartados clave de las normas ISO 8-1977 e ISO 215-1986. A partir de la observación directa de los fascículos, se han confeccionado dos índices para calcular el Grado General de Normalización (GGN) y el Grado Fundamental de Normalización (GFN). Los resultados indican que el ajuste de las publicaciones a la norma ISO 8-1977 es equivalente a la de otros campos españoles como el de Economía y el de Tecnología, mientras que es menor en la norma ISO 215-1986. La mayoría de las revistas presentan un …

Mitochondria-related encephalomyopathies.

1989

Owing to advances in morphological and biochemical techniques, the mitochondria-related myopathies and encephalomyopathies have emerged as a still rapidly growing group of primary and secondary metabolic disorders, which may extend from infancy to late adulthood. Impairment of the biochemically diversified mitochondria is reflected in an enormous number of deficiencies, often affecting several mitochondrial enzymes in the same patient; morphologically abnormal mitochondria are common and are thus not specific to individual mitochondrial enzyme deficiencies. Skeletal muscle biopsies have provided a wealth of data through histological and histochemical studies and from isolated mitochondria. …

Myoglobin on Silica: A Case Study of the Impact of Adsorption on Protein Structure and Dynamics

2013

International audience; If protein structure and function changes upon adsorption are well documented, modification of adsorbed protein dynamics remains a blind spot, despite its importance in biological processes. The adsorption of metmyoglobin on a silica surface was studied by isotherm measurements, microcalorimetry, circular dichroïsm, and UV-visible spectroscopy to determine the thermodynamic parameters of protein adsorption and consequent structure modifications. The mean square displacement and the vibrational densities of states of the adsorbed protein were measured by elastic and inelastic neutron scattering experiments. A decrease of protein flexibility and depletion in low freque…

Response spectrum analysis of frame structures: reliability-based comparison between complete quadratic combination and damping-adjusted combination

2019

In the framework of seismic design of structures, response spectrum analysis (RSA) is the most commonly used approach in practice. The most popular combination rule is the complete quadratic combination (CQC) which is also prescribed by the most of seismic design codes and is based on the assumptions that the seismic acceleration is a white noise process and the peak factor ratios associated to the total and modal responses are unitary. Recently, the damping adjusted combination (DAC) rule has been developed for base-isolated structures to overcome the aforementioned simplified assumptions. Although it has been proved that the simplifications about peak factors lead to noticeable errors in …

Approximate renormalization-group transformation for Hamiltonian systems with three degrees of freedom

1999

We construct an approximate renormalization transformation that combines Kolmogorov-Arnold-Moser (KAM)and renormalization-group techniques, to analyze instabilities in Hamiltonian systems with three degrees of freedom. This scheme is implemented both for isoenergetically nondegenerate and for degenerate Hamiltonians. For the spiral mean frequency vector, we find numerically that the iterations of the transformation on nondegenerate Hamiltonians tend to degenerate ones on the critical surface. As a consequence, isoenergetically degenerate and nondegenerate Hamiltonians belong to the same universality class, and thus the corresponding critical invariant tori have the same type of scaling prop…

Sun exposure and PDZK1 genotype modulate PDZK1 gene expression in normal skin

2020

Human skin pigmentation results from the enzymatically controlled synthesis of melanin pigments in specialized organelles (melano‐somes) produced within epidermal melanocytes, followed by their transfer to neighboring keratinocytes and their distribution through‐out the epidermis.1 Constitutive skin pigmentation seems to be mostly genetically determined,2 being altered by numerous intrinsic and extrinsic factors affecting the epidermal melanin unit