Search results for "Nose"
showing 10 items of 1793 documents
Organizzazioni del terzo settore
2021
When referring to migrants, the collective representation sees them as recipients of services offered by the third sector and not, in the first instance, as actors actively engaged in associative processes. Addressing the issue of the relationship between migrants and the third sector implies, therefore, proposing a change of perspective that leads to think of migrants (also this rather wide category) not as direct beneficiaries, as victims in need, but as protagonists actively engaged in the institutions or as collaborators, experts, employees, therefore paid, or as volunteers, free of charge.
Nonlinear Optical Characterization of InP@ZnS Core-Shell Colloidal Quantum Dots Using 532 nm, 10 ns Pulses
2021
InP@ZnS core-shell colloidal quantum dots (CQDs) were synthesized and characterized using the z-scan technique. The nonlinear refraction and nonlinear absorption coefficients (γ = −2 × 10−12 cm2 W−1, β = 4 × 10−8 cm W−1) of these CQDs were determined using 10 ns, 532 nm pulses. The saturable absorption (β = −1.4 × 10−9 cm W−1, Isat = 3.7 × 108 W cm−2) in the 3.5 nm CQDs dominated at small intensities of the probe pulses (I ≤ 7 × 107 W cm−2) followed by reverse saturable absorption at higher laser intensities. We report the optical limiting studies using these CQDs showing the suppression of propagated nanosecond radiation in the intensity range of 8 × 107–2 × 109 W cm−2. The role of nonline…
Psychoeducational Challenges in Spanish Children With Dyslexia and Their Parents’ Stress During the COVID-19 Pandemic
2021
BackgroundResearch during 2020 has been rapidly attending to the impact of COVID-19 on various dimensions of wellbeing (e.g., physical, psychological, lifestyle and routines) on adults and children around the world. However, less attention has focused on the psychoeducational impact on children and their families. To our knowledge, no currently available studies have looked specifically at the impact of COVID-19 on students with dyslexia and their families. Research on this topic is needed to offer greater support for this population of students and their families.ObjectiveThe main objective of this paper is to examine the psychoeducational impact of the required COVID-19 quarantine in Spai…
CHILDREN’S DEPRESSION RATING SCALE-REVISED (CDRS-R) – DEVELOPMENT OF THE LATVIAN VERSION AND PSYCHOMETRIC PROPERTIES IN A CLINICAL AND NON-CLINICAL S…
2019
Depression is one of the most widespread mental disorders worldwide. Adolescence is a vulnerable period for developing depression. It is associated with a number of challenges in biological, psychological and social areas. Valid and reliable measurement instruments are required for assessment of symptoms of depression in clinical samples of adolescents in Latvia. Children's Depression Rating Scale Revised (CDRS-R, Posnanski & Mokros, 1996) is a semi-structured, clinician-rated interview for assessment of depression in children and adolescents. While the CDRS-R is the most widely used rating scale for research and clinicians’ practical use worldwide, there's no validated version in Latvi…
The role of self-compassion in the relationship between attachment, depression, and quality of life.
2019
Abstract Background Self-compassion may be shaped by early attachment experiences, and has been linked to mental health and well-being. This study examined the role of two distinct features of self-compassion, self-warmth and self-coldness, in the relationship between attachment insecurity and depression as well as quality of life in a general population sample in Germany. Methods Participants (N = 2,253; 53.4% female, Mage 50 years) completed the Self-Compassion Scale (SCS), Adult Attachment Scale (AAS), Beck Depression Inventory-Fast Screen (BDI-FS), and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30). Mediation analysis was used to…
Low intensity vs. self-guided Internet-delivered psychotherapy for major depression: A multicenter, controlled, randomized study
2013
Abstract Background Major depression will become the second most important cause of disability in 2020. Computerized cognitive-behaviour therapy could be an efficacious and cost-effective option for its treatment. No studies on cost-effectiveness of low intensity vs self-guided psychotherapy has been carried out. The aim of this study is to assess the efficacy of low intensity vs self-guided psychotherapy for major depression in the Spanish health system. Methods The study is made up of 3 phases: 1.- Development of a computerized cognitive-behaviour therapy for depression tailored to Spanish health system. 2.- Multicenter controlled, randomized study: A sample (N=450 patients) with mild/mod…
Diagnoses as Selection Criteria in Drug Trials
1990
Drug trials are needed to establish the efficacy and safety of psychopharmacological agents in clearly defined indications. When the goal of treatment is more complex than removal of an isolated symptom (“difficulty in falling asleep” or “pain”) the syndrome or clinical entity to be treated is most easily classified by way of a diagnostic label (like “depression,” “schizophrenia,” or “panic disorder”). Dimensional models have many advantages: they often fit the data better and provide a conceptual framework for a continuum in the behavior from normal to abnormal. However, they have never reached the popularity of typological models (Strauss 1973, 1975, 1986) which reflect more the medical t…
Human NCL Neuropathology
2015
AbstractThe neuronal ceroid lipofuscinoses (NCL) currently encompass fourteen genetically different forms, CLN1 to CLN14, but are all morphologically marked by loss of nerve cells, particularly in the cerebral and cerebellar cortices, and the cerebral and extracerebral formation of lipopigments. These lipopigments show distinct ultrastructural patterns, i.e., granular, curvilinear/rectilinear and fingerprint profiles. They contain−although to a different degree among the different CLN forms−subunit C of ATP synthase, saposins A and D, and beta-amyloid proteins. Extracerebral pathology, apart from lipopigment formation, which provides diagnostic information, is scant or non-existent. The ret…
Retinal ultrastructure of neuronal ceroid-lipofuscinosis in the Dalmatian dog
1985
Ultrastructural studies of the retinae in two NCL-affected Dalmatian dogs revealed ubiquitous accumulation of lipopigments in numerous cell types of the retina, the fine structure of which closely resembled that seen in NCL-affected English setters. Photoreceptors and other retinal cell types were largely intact. These findings show that the retinal involvement in NCL of our Dalmatian dogs is identical to that of NCL-affected English setters. It also shows that in canine NCL a severe retinopathy, regularly encountered in human childhood NCL, does not develop. Thus, the NCL of Dalmatian dogs —and English setters — represents a reliable model to study human NCL, but for human retinopathia pig…
Retina in various animal models of neuronal ceroid-lipofuscinosis
1992
The childhood forms of human neuronal ceroid-lipofuscinosis (NCL) are invariably associated with a severe progressive retinopathy which commences at the photoreceptor level morphologically and proceeds to a final loss of neuronal cells accompanied by severe gliosis. In respective spontaneous animal conditions of NCL, in English setters, Dalmatian dogs, and New Zealand sheep, retinal involvement is not commensurate although the retina does not seem to be completely unaffected. In canine NCL, there might be functional and electro-physiological impairment of retinal cells, but retinal atrophy is not obvious. In ovine NCL, the retina, apart from accumulating NCL-specific lipopigments within neu…