Search results for "Note"
showing 10 items of 10709 documents
Physicochemical stability of irinotecan injection concentrate and diluted infusion solutions in PVC bags
2000
Purpose. To determine the physicochemical stability of irinotecan injection concentrate and irinotecan infusion solutions after dilution in two commonly used infusion fluids (0.9% sodium chloride, 5% dextrose) in PVC bags, stored under refrigeration (2-8°C) or at room temperature either light protected or exposed to light. Methods. Stability of irinotecan injection concentrate was determined in the original amber glass vials. Diluted irinotecan infusion solutions were aseptically prepared by further dilution of irinotecan stock solution with either 0.9% sodium chloride or 5% dextrose in PVC bags, in amounts yielding irinotecan concentrations of 0.4, 1.0, or 2.8 mg/ml. Test solutions were s…
The influence of NiTi alloy on the cyclic fatigue resistance of endodontic files
2020
Background: The aim of this study was to analyze the influence of NiTi alloy in endodontic rotary instruments on cyclic fatigue resistance. Methods: One hundred and sixty-four (164) sterile endodontic rotary files were selected and distributed into the following study groups: A: 25.08 F2 ProTaper Universal (PTU) (n = 41)
Unpredictable Performance of pH-Dependent Coatings Accentuates the Need for Improved Predictive in Vitro Test Systems.
2017
First introduced in the second half of the 19th century, enteric coatings are commonly used to protect acid-labile drugs, reduce the risk of gastric side effects due to irritating drugs, or for local drug delivery to the lower gastrointestinal (GI) tract. The currently available enteric-coatings are based on pH-sensitive weakly acidic polymers. Despite the long history of their use, the causes behind their performance often being unpredictable have not been properly investigated with most of the attention being focused only on the gastric emptying. However, little attention has been given to the postgastric emptying disintegration and dissolution of these dosage forms. This lack of attentio…
Towards the Point of Care and Noninvasive Classification of Bladder Cancer from Urine Sediment Infrared Spectroscopy. Spectral differentiation of nor…
2021
Abstract Bladder cancer (BC) is the 9th cancer cause of death and one of most cost-intensive in the world. The diagnostic tools are still not at all satisfactory. Herein we evaluated the potential of infrared spectroscopy to detect molecular changes that precede and accompany the carcinogenesis in voided urine sediment. We collected 165 samples from patients being diagnosed for BC and measured them with attenuated total reflectance Fourier transformed infrared spectroscopy (ATR FTIR). Samples were primarily divided into three groups according to cytology that indicated the presence of normal, abnormal and cancer cells. ATR FTIR spectra of sediments were analyzed with the use of partial leas…
Visualizing the atherosclerotic plaque: a chemical perspective.
2014
Atherosclerosis is the major underlying pathologic cause of coronary artery disease. An early detection of the disease can prevent clinical sequellae such as angina, myocardial infarction, and stroke. The different imaging techniques employed to visualize the atherosclerotic plaque provide information of diagnostic and prognostic value. Furthermore, the use of contrast agents helps to improve signal-to-noise ratio providing better images. For nuclear imaging techniques and optical imaging these agents are absolutely necessary. We report on the different contrast agents that have been used, are used or may be used in future in animals, humans, or excised tissues for the distinct imaging moda…
A New Absorbable Synthetic Substitute With Biomimetic Design for Dural Tissue Repair
2015
Dural repair products are evolving from animal tissue-derived materials to synthetic materials as well as from inert to absorbable features; most of them lack functional and structural characteristics compared with the natural dura mater. In the present study, we evaluated the properties and tissue repair performance of a new dural repair product with biomimetic design. The biomimetic patch exhibits unique three-dimensional nonwoven microfiber structure with good mechanical strength and biocompatibility. The animal study showed that the biomimetic patch and commercially synthetic material group presented new subdural regeneration at 90 days, with low level inflammatory response and minimal …
Influence of compression sportswear on recovery and performance: A systematic review
2018
Compression garments are becoming increasingly popular among sportspeople who wish to improve performance and reduce their exercise discomfort and risk of injury. However, evidence for such effects is scarce. This paper presents the evidence following a review of the literature evaluating the effects of the application of compression garments on sports performance and recovery after exercise. The literature reviewed was the result of a search on the Web of Science, PubMed, and SPORTDiscus electronic databases for studies which analysed the effect of compression garments on physiological, psychological, and biomechanical parameters during and after exercise. These search criteria were met b…
Running thermoregulation effects using bioceramics versus polyester fibres socks
2020
The feet, covered by socks and shoes during running, undergo an increase of temperature. The aim of this study was to reduce heat generation in the feet of athletes during running by wearing novel thermoregulatory socks impregnated with bioceramic materials. Thirty male athletes ran a half-marathon (21.0975 km) wearing polyester based with bioceramic fibres (zirconium silicate and titanium oxide) and control socks (polyester). The average temperatures were measured with a thermographic camera (FLIR e60bx) before and after the run. Nine regions of interests were evaluated in the plantar surface and eight in the dorsum. Before running, the plantar region with the highest temperature was the …
Effects of a fatiguing run in popliteal vein flow using sports compression socks
2018
Introduction Although the use of sports compression socks is becoming more popular, there is still a lack of knowledge regarding the helpfulness of these garments for physical movement or sports use. One of the main effects attributed to the use of compression sock is the facilitation of venous blood flow return which is thought to improve performance and recovery. Methodology In this study, 10 trained runners performed 2 treadmill running tests for 30 min to 75% of their maximum aerobic speed, without sports socks (control) and with different sports compression socks. We measured popliteal vein flow volume before and after each test using magnetic resonance imaging. Results and discussion …
The Effect of surface topographical changes of two different surface treatments rotary instrument
2018
Background One of the major innovations in endodontics has been the introduction of nickel-titanium (NiTi) alloy. This study evaluated the surface topographical changes of two different surface treatments rotary instrument after instrumentation and sterilization. Material and Methods 240 Extracted teeth were included in this study. 90 new AlphaKite and Revo-S NiTi rotary instruments were selected and divided into two groups (Group A 45 AlphaKite and group B 45 Revo-S). Each group were divided into three subgroups: (A1, B1) n=5 files were used as a control, (A2,B2) n=20 files were used to prepare three root canals using endodontic rotary motor then sterilized by autoclave for one cycle under…