Search results for "Note"
showing 10 items of 10709 documents
Towards Laser-Textured Antibacterial Surfaces
2018
AbstractEscherichia coli and Staphylococcus aureus bacterial retention on mirror-polished and ultrashort pulse laser-textured surfaces is quantified with a new approach based on ISO standards for measurement of antibacterial performance. It is shown that both wettability and surface morphology influence antibacterial behavior, with neither superhydrophobicity nor low surface roughness alone sufficient for reducing initial retention of either tested cell type. Surface structures comprising spikes, laser-induced periodic surface structures (LIPSS) and nano-pillars are produced with 1030 nm wavelength 350 fs laser pulses of energy 19.1 μJ, 1.01 μJ and 1.46 μJ, respectively. SEM analysis, optic…
Hydroxypropylcellulose as a novel green reservoir for the synthesis, stabilization, and storage of silver nanoparticles
2015
Muhammad Ajaz Hussain,1 Abdullah Shah,1 Ibrahim Jantan,2 Muhammad Raza Shah,3 Muhammad Nawaz Tahir,4 Riaz Ahmad,5 Syed Nasir Abbas Bukhari2 1Department of Chemistry, University of Sargodha, Sargodha, Pakistan; 2Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Malaysia; 3International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan; 4Institute of Inorganic and Analytical Chemistry, Johannes Guttenberg University, Duesbergweg, Mainz, Germany; 5Centre for Advanced Studies in Physics (CASP), GC University, Lahore, Pakistan Abstract: Polysaccharides are attracting the vigil eye of…
Discovery of 2-aryl and 2-pyridinylbenzothiazoles endowed with antimicrobial and aryl hydrocarbon receptor agonistic activities
2020
Highlights • Sixteen functionalized benzothiazoles were evaluated as antimicrobial agents and as AhR modulators. • The benzothiazoles showed noticeable antimicrobial effects against Gram-positive and Gram-negative pathogens and against the yeast C. albicans. • Six benzothiazoles exhibited significant AhR agonist effects in a cell-based reporter gene assay. • Structure-activity relationship analysis exposed some relevant headings on the substituent's contributions to the studied biological effects. • Compound 12 displayed promising biocide activity and AhR agonism as well as an adequate ADMET profile and binding similarities with FICZ.
Elpceļu infekciju gadījumos izdalīto Staphylococcus aureus jutība pret antibakteriālajiem līdzekļiem
2017
S.aureus ir gram + pozitīva baktērija, kas ir lokalizējusies degunā elpošanas traktā un uz ādas un ne vienmer ir patogēns mikroorganisms. Spēj ģēnētiski izmainīt savu šūnapvalka olbaltumvielas, padarot tos rezistentus pret antibiotikām. Meticilīn-rezistentais S. aureus (MRSA) satur mecA gēnu, kas nodrošina mikroorganismam rezistenci ne tikai pret meticilīnu un b - laktāma grupas antibiotikām, bet arī pret cefalosporīniem un citām grupām. Rezistences attīstība patogēniem ir saistīta ar plašu un bieži nepamatotu antibiotiku lietošanu terapijā. Darba mērķis: Noteikt S. aureus jutību pret antibakteriālajiem līdzekļiem, celmiem, kas izdalīti no elpceļu materiāla. Darba uzdevumi: Veikt laboratori…
Using neural networks to obtain indirect information about the state variables in an alcoholic fermentation process
2020
This work provides a manual design space exploration regarding the structure, type, and inputs of a multilayer neural network (NN) to obtain indirect information about the state variables in the alcoholic fermentation process. The main benefit of our application is to help experts reduce the time needed for making the relevant measurements and to increase the lifecycles of sensors in bioreactors. The novelty of this research is the flexibility of the developed application, the use of a great number of variables, and the comparative presentation of the results obtained with different NNs (feedback vs. feed-forward) and different learning algorithms (Back-Propagation vs. Levenberg&ndash
Extent of the influence of phosphate buffer and ionic liquids on the reduction of the silanol effect in a C18 stationary phase
2017
The presence of anionic free silanols in the silica-based stationary phases gives rise to broad and asymmetrical peaks when cationic basic compounds are chromatographed using hydro-organic mobile phases. The addition to the mobile phase of a reagent with ionic character prevents the access of analytes to the free silanols, improving the peak shape. The silanol activity can be affected by the buffer concentration and mobile phase pH, factors that are not always considered sufficiently in the literature. In this work, the chromatographic behaviour of three basic β-adrenoceptor antagonists (acebutolol, nadolol and timolol), using mobile phases containing acetonitrile, was examined at different…
Strongly confined fluids: Diverging time scales and slowing down of equilibration
2016
The Newtonian dynamics of strongly confined fluids exhibits a rich behavior. Its confined and unconfined degrees of freedom decouple for confinement length $L \to 0$. In that case and for a slit geometry the intermediate scattering functions $S_{\mu\nu}(q,t)$ simplify, resulting for $(\mu,\nu) \neq (0,0)$ in a Knudsen-gas like behavior of the confined degrees of freedom, and otherwise in $S_{\parallel}(q,t)$, describing the structural relaxation of the unconfined ones. Taking the coupling into account we prove that the energy fluctuations relax exponentially. For smooth potentials the relaxation times diverge as $L^{-3}$ and $L^{-4}$, respectively, for the confined and unconfined degrees of…
Sub-threshold signal processing in arrays of non-identical nanostructures
2011
Weak input signals are routinely processed by molecular-scaled biological networks composed of non-identical units that operate correctly in a noisy environment. In order to show that artificial nanostructures can mimic this behavior, we explore theoretically noise-assisted signal processing in arrays of metallic nanoparticles functionalized with organic ligands that act as tunneling junctions connecting the nanoparticle to the external electrodes. The electronic transfer through the nanostructure is based on the Coulomb blockade and tunneling effects. Because of the fabrication uncertainties, these nanostructures are expected to show a high variability in their physical characteristics and…
Traitpedia: a collaborative effort to gather species traits
2018
Abstract Summary Traitpedia is a collaborative database aimed to collect binary traits in a tabular form for a growing number of species. Availability and implementation Traitpedia can be accessed from http://cbdm-01.zdv.uni-mainz.de/~munoz/traitpedia. Supplementary information Supplementary data are available at Bioinformatics online.
CROSSMAPPER: estimating cross-mapping rates and optimizing experimental design in multi-species sequencing studies
2020
Motivation Numerous sequencing studies, including transcriptomics of host-pathogen systems, sequencing of hybrid genomes, xenografts, mixed species systems, metagenomics and meta-transcriptomics, involve samples containing genetic material from divergent organisms. A crucial step in these studies is identifying from which organism each sequencing read originated, and the experimental design should be directed to minimize biases caused by cross-mapping of reads to incorrect source genomes. Additionally, pooling of sufficiently different genetic material into a single sequencing library could significantly reduce experimental costs but requires careful planning and assessment of the impact of…