Search results for "Novas"
showing 10 items of 30 documents
Forutsetninger for vellykket sosial innovasjon i sykehjem: ledernes perspektiv – en kvalitativ intervjustudie
2019
Preconditions for successful social innovation in nursing homes: Managers' perspectives - a qualitative interview studyIn this article, we investigate preconditions for social innovation in institution-based elderly care in Norway and Denmark. The article draws on two semi-structured interviews and one focus-group interview. The interviewees are managers in elderly-care facilities that are known to be proficient with regards to innovation. The analysis point to three principles managers describe as being pertinent to successful social innovation. Firstly, an overall theme across the interviews was that the managers underscored the importance of eagerness and willingness to change as a prere…
Experiences with Blockade of the Renin System in Human Hypertension Using Converting Enzyme Inhibitor SQ 20,881 and Saralasin
1980
The development of agents which are capable of producing in vivo angiotensin II blockade has provided to investigators and clinicians alike the opportunity to determine and to quantify the extent to which the renin-angiotensin system participates in the maintenance of hypertensive states. High levels of plasma renin activity relative to the state of sodium balance have been documented in patients with malignant, surgically remediable renovascular hypertension and also in some patients with essential hypertension.1 The recent development of the angiotensin II analogue sar1-ala8-angiotensin II (saralasin) provided evidence to support the concept that these elevated renin levels are in fact pa…
Takayasu's disease effects on the kidneys: current perspectives.
2018
Takayasu arteritis (TA) is a chronic vasculitis disease of unknown etiology. Clinically significant renal disease is relatively common, and renovascular hypertension is the major renal problem. The assessment of TA activity is usually challenging because vascular inflammation may progress to fixed vascular injury without findings of active disease. Until now, the best therapeutic options have not been identified. This review highlights the current perspectives of renal involvement in TA.
Hyperuricemia and non-dipping blood pressure
2013
Dear editor The strong association between the metabolic derangements that characterize the metabolic syndrome with arterial hypertension is very well-known, as it is the common finding of hyperuricemia in the patients with the metabolic syndrome. Besides, hyperuricemia has been found to be associated with cardiovascular, renal, and metabolic diseases; including not only gout but also type 2 diabetes mellitus, although its role as a risk factor is still debated.1 We were not aware of previous studies describing an association between uric acid levels and the non-dipping 24-hour blood pressure (BP) pattern, and for that reason we were intrigued by Tutal et al’s article, regarding hypertensiv…
Migraine and cluster headache – the common link
2018
Abstract Although clinically distinguishable, migraine and cluster headache share prominent features such as unilateral pain, common pharmacological triggers such glyceryl trinitrate, histamine, calcitonin gene-related peptide (CGRP) and response to triptans and neuromodulation. Recent data also suggest efficacy of anti CGRP monoclonal antibodies in both migraine and cluster headache. While exact mechanisms behind both disorders remain to be fully understood, the trigeminovascular system represents one possible common pathophysiological pathway and network of both disorders. Here, we review past and current literature shedding light on similarities and differences in phenotype, heritability…
Other Methods to Assess Renal Damage
2015
Although glomerular filtration rate (GFR) and proteinuria remain gold standard in the evaluation of renal target organ damage, imaging techniques and image-derived parameters allow for both assessment of renal function and estimation of cardiovascular risk. Enhancement in digital image processing permits dynamic measurement of renal vascular and intraparenchymal processes in real time. The most relevant in terms of clinical use to assess hypertension-induced organ damage are the renal resistive index (RRI), renal calcium score, and functional magnetic resonance imaging.
Evaluation von Nierenarterienstenosen: Vergleich von Angiographie mit invasiver Blutdruckmessung und Doppler-Sonographie
2000
Ziel: Der bei einer Nierenarterien-Angioplastie angiographisch gemessene Stenosegrad soll mit dem transstenotischen Blutdruck-Gradienten und dem prainterventionellen dopplersonographischen Befund verglichen werden. Methoden: Anhand von insgesamt 46 Nierenarterienstenosen bei 35 Patienten mit renovaskularer Hypertonie werden die angiographisch-morphologischen Befunde („linearer”, „geometrischer” und „densitometrischer” Stenosegrad) mit der invasiven transstenotischen Blutdruckmessung und den prainterventionellen Doppler-Befunden verglichen. Ergebnisse: Alle angiographisch bestimmten Stenosegrade korrelieren - masig - mit den transstenotischen Druckgradienten (Korrelationskoeffizienten: 0,67 …
99mTc–MAG3–Nierenfunktionsszintigraphie ohne und mit Captopril zur Diagnostik der renovaskulären Hypertonie
1993
In this study, the diagnostic value of renal function scintigraphy performed both without and with ACE inhibition has been evaluated using the new radiopharmaceutical 99mTc-MAG3. In cases of decompensated renal artery stenoses, the typical scan finding with this tubular excreted agent was shown to be a distinct parenchymal nuclide retention in combination with a delayed appearance of the radiotracer in the pelvic system. Using this criterion in 43 patients with suspected renovascular hypertension, sensitivity and specificity were 89 and 88%, respectively. Bilateral positive findings were non-specific; excluding them from the study, specificity increased to 100%. In renal insufficiency, capt…
"Ikke alle piloter flyr" : implementering av telemedisin i norske kommuner
2019
Masteroppgave helse- og sosialinformatikk HSI500 - Universitetet i Agder 2019 Running pilots is a widespread way of conducting innovations in the Norwegian health service, many of these projects are not implemented permanently or lead to lasting changes in services. Solutions based on Telemedicine are being tested, but the implementation rate does not match the existing ambitions. The aim of this study is to gain increased knowledge of some of the factors that are required for pilot projects in Telemedicine to go from pilots to permanent solutions, especially focused on stakeholders and their role. The thesis question is «What is the significance of different stakeholders in the municipalit…
Past, present, and future of green product innovation
2021
Firms are under constant pressure from various governmental and nongovernmental agencies to switch from conventional environmentally polluting products to green product innovations (GPIs). However, the relevant research pertaining to GPI has been published in a diverse set of journals that vary in their scope and readership and, therefore, the scholarly contribution to the topic remains largely fragmented. This study has utilised a systematic literature review approach to examine the literary corpus on GPI to paint a holistic picture of its different aspects. The content and thematic analysis of 85 studies resulted in the extraction of seven key research themes: organisational capabilities,…