Search results for "Ntic"

showing 10 items of 6004 documents

Correction to: Adjunctive Brivaracetam in Focal Epilepsy: Real‑World Evidence from the BRIVAracetam add‑on First Italian netwoRk Study (BRIVAFIRST)

2021

In randomized controlled trials, add-on brivaracetam (BRV) reduced seizure frequency in patients with drug-resistant focal epilepsy. Studies performed in a naturalistic setting are a useful complement to characterize the drug profile.This multicentre study assessed the effectiveness and tolerability of adjunctive BRV in a large population of patients with focal epilepsy in the context of real-world clinical practice.The BRIVAFIRST (BRIVAracetam add-on First Italian netwoRk STudy) was a retrospective, multicentre study including adult patients prescribed adjunctive BRV. Patients with focal epilepsy and 12-month follow-up were considered. Main outcomes included the rates of seizure-freedom, s…

AdultMaleDrug Resistant EpilepsyLevetiracetamEpilepsy CNS therapyCorrectionMiddle AgedSettore MED/26PyrrolidinonesPsychiatry and Mental healthTreatment OutcomeItalyChemotherapy AdjuvantHumansPharmacology (medical)AnticonvulsantsFemaleNeurology (clinical)Epilepsies PartialRetrospective Studies
researchProduct

Effectiveness of eslicarbazepine acetate in dependency of baseline anticonvulsant therapy: Results from a German prospective multicenter clinical pra…

2019

Abstract Eslicarbazepine acetate (ESL) is a third-generation antiepileptic drug (AED) approved as monotherapy for partial-onset seizures in adults and as adjunctive therapy in patients aged above 6 years in the European Union (EU). The prospective observational Zebinix Effects in DEpendency of BAseline Conditions (ZEDEBAC) study aimed at investigating the effectiveness of ESL in clinical practice, with ESL being administered as monotherapy (mono group), as only add-on to a current monotherapy (1 + group), or as add-on to ≥ 2 baseline AEDs (≥ 2 + group). In total, 237 patients were included, 35 in the mono group, 114 in the 1 +, and 88 in the ≥ 2 + group. Six-month retention rates were 93.9%…

AdultMaleDrug Resistant Epilepsymedicine.medical_specialtyYoung Adult03 medical and health sciencesBehavioral NeuroscienceEpilepsy0302 clinical medicineSodium channel blockerRefractoryDibenzazepinesSeizuresInternal medicineHumansMedicinemedia_common.cataloged_instanceProspective Studies030212 general & internal medicineEuropean unionAgedmedia_commonbusiness.industryMiddle Agedmedicine.diseaseNeurologyEslicarbazepine acetateConcomitantAnticonvulsantsFemaleObservational studyNeurology (clinical)businessHyponatremia030217 neurology & neurosurgerySodium Channel Blockersmedicine.drugEpilepsy & Behavior
researchProduct

Neuronal and Behavioral Correlates of Health Anxiety: Results of an Illness-Related Emotional Stroop Task

2011

<b><i>Background:</i></b> Health anxiety (HA) is defined as the objectively unfounded fear or conviction of suffering from a severe illness. Predominant attention allocation to illness-related information is regarded as a central process in the development and maintenance of HA, yet little is known about the neuronal correlates of this attentional bias. <b><i>Methods:</i></b> An emotional Stroop task with body symptom, illness, and neutral words was employed to elicit emotional interference in healthy participants with high (HA+, n = 12) and low (HA–, n = 12) HA during functional magnetic resonance imaging. <b><i>Results:</i>…

AdultMaleEmotionsmacromolecular substancesAnxietyNeuropsychological TestsAttentional biasVocabularyYoung AdultImage Processing Computer-AssistedReaction TimemedicineHumansBiological PsychiatryAnterior cingulate cortexAnalysis of VarianceBrain Mappingmedicine.diagnostic_testBrainMagnetic Resonance ImagingSemanticsOxygenPsychiatry and Mental healthNeuropsychology and Physiological Psychologymedicine.anatomical_structureConvictionAnxietyFemaleSelf Reportmedicine.symptomPsychologyFunctional magnetic resonance imagingPhotic StimulationStroop effectCognitive psychologyNeuropsychobiology
researchProduct

Effect of posterior gingival smile on the perception of smile esthetics

2013

Objectives: To evaluate and compare the influence of posterior gummy smile on the perception of smile esthetics by orthodontists, general-dentists and laypersons. Study Design: A frontal photograph of a smile with normal gum exposure was chosen and manipulated digitally using Adobe Photoshop C3 to generate three further images with posterior gum exposure of 4, 6 and 8mm. These four images were assessed by the three evaluator groups: orthodontists (n=40), general-dentists (n=40) and laypersons (n=40). Both orthodontists and dentists had at least ten years professional experience and laypersons were aged between 40-50 years. The proportion of men to women was 20:20 in each group. Evaluators a…

AdultMaleEstheticsmedia_common.quotation_subjectGingivaAdobe photoshopDentistryOrthodonticsOdontologíaSmilingPerceptionGummy smileClinical and Experimental DentistrySurveys and QuestionnairesMedicineHumansGeneral Dentistrymedia_commonOrthodonticsbusiness.industryResearchMiddle Aged:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludOtorhinolaryngologyAttitudeDentistryUNESCO::CIENCIAS MÉDICASSurgeryFemalebusiness
researchProduct

On the flexibility of letter position coding during lexical processing: Evidence from eye movements when reading Thai

2012

Previous research supports the view that initial letter position has a privileged role in comparison to internal letters for visual-word recognition in Roman script. The current study examines whether this is the case for Thai. Thai is an alphabetic script in which ordering of the letters does not necessarily correspond to the ordering of a word's phonemes. Furthermore, Thai does not normally have interword spaces. We examined whether the position of transposed letters (internal, e.g., porblem, vs. initial, e.g., rpoblem) within a word influences how readily those words are processed when interword spacing and demarcation of word boundaries (using alternatingbold text) is manipulated. The …

AdultMaleEye MovementsPhysiologyExperimental and Cognitive PsychologyFixation OcularMental ProcessesPhysiology (medical)Reaction TimeHumansAttentionStudentsGeneral PsychologyLanguageVisual word recognitionEye movementLatin scriptRecognition PsychologyGeneral MedicineThailandLinguisticsSemanticsNeuropsychology and Physiological PsychologyPattern Recognition VisualReadingFemalePsychologyCoding (social sciences)Quarterly Journal of Experimental Psychology
researchProduct

Famous face recognition and naming test: a normative study.

2003

Tests of famous face recognition and naming, and tasks assessing semantic knowledge about famous people after presentation either of their faces or their names are often used in the neuropsychological examination of aphasic, amnesic and demented patients. A total of 187 normal subjects took part in this study. The aim was to collect normative data for a newly devised test including five subtests: famous face naming, fame judgement after face presentation and after name presentation, semantic knowledge about famous people after face presentation and after name presentation. Norms were calculated taking into account demographic variables such as age, sex and education and adjusted scores were…

AdultMaleFamous Personsmedia_common.quotation_subjectFace PresentationJudgementFace (sociological concept)DermatologyNeuropsychological Testsbehavioral disciplines and activitiesPresentationAge DistributionReference ValuesSemantic memoryHumansSex Distributionmedia_commonAgedVerbal BehaviorNeuropsychologyAge FactorsRecognition PsychologyGeneral MedicineMiddle AgedhumanitiesTest (assessment)Psychiatry and Mental healthItalyPattern Recognition VisualFaceNormativeEducational StatusRegression AnalysisFemaleNeurology (clinical)PsychologySocial psychologypsychological phenomena and processesCognitive psychologyNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
researchProduct

Perceptual and semantic familiarity in recognition memory: an event-related potential study

2008

Putative event-related potential correlates of perceptual and semantic bases of familiarity in recognition memory were examined with a categorized pictures recognition test. Our participants were presented, at study, with pictures of categorized objects and, at test, with either the very same pictures presented at study, different pictures of studied objects, pictures of new objects belonging to studied categories, or pictures of completely new-uncategorized objects. We found evidence for a parallel evaluation, within familiarity process, of both perceptual and semantic information. We also found new and interesting evidence for the existence of some common neural circuits involved in the F…

AdultMaleGeneral NeuroscienceMemoriamedia_common.quotation_subjectComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISIONRecognition PsychologyCognitionSemanticsTest (assessment)ComputingMethodologies_PATTERNRECOGNITIONMemoryEvent-related potentialPerceptionEvoked Potentials VisualHumansFemalePerceptionPsychologyPhotic StimulationCognitive psychologyRecognition memorymedia_commonNeuroReport
researchProduct

Prevalence of fimA genotypes of Porphyromonas gingivalis and other periodontal bacteria in a Spanish population with chronic periodontitis

2012

Objectives: The aim of this study was to determine the prevalence of the different fimA genotypes of Porphyromonas gingivalis in adult Spanish patients with chronic periodontitis, patients with gingivitis and periodontally healthy subjects, and the relationship between these genotypes and other periodontopathogenic bacteria. Study design: Samples of subgingival plaque were taken from 86 patients (33 with chronic periodontitis, 16 with gingivitis, and 37 periodontally healthy) in the course of a full periodontal examination. PCR was employed to determine the presence of the 6 fimA genotypes of Porphyromonas gingivalis (I-V and Ib) and of Aggregatibacter actinomycetemcomitans, Tannerella fors…

AdultMaleGenotypePeriodontal examinationDentistryOdontologíaMicrobiologyGingivitismedicineTannerella forsythiaHumansPeriodontologyGeneral DentistryPorphyromonas gingivalisPeriodontitisbiologybusiness.industryAggregatibacter actinomycetemcomitansTreponema denticolabiochemical phenomena metabolism and nutritionMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseasebiology.organism_classificationCiencias de la saludChronic periodontitisstomatognathic diseasesOtorhinolaryngologySpainUNESCO::CIENCIAS MÉDICASChronic PeriodontitisbacteriaSurgeryResearch-ArticleFemaleFimbriae Proteinsmedicine.symptombusinessPorphyromonas gingivalisMedicina Oral, Patología Oral y Cirugía Bucal
researchProduct

Orthodontic treatment need in a Spanish young adult population

2011

Objectives: Orthodontic treatment need has often been assessed in child populations, but few studies employing internationally-recognized indices have been conducted in adult or young adult populations. The aim of this study was to determine the orthodontic treatment need of a young adult population in Spain by means of the Dental Aesthetic Index (DAI), the Index of Orthodontic Treatment Need (IOTN) and the need perceived by the patients. Study design: A cross-sectional epidemiological study was conducted in a broad, representative sample of 671 adults aged between 35 and 44 years using health centers in the Valencia Region of Spain, following the recommendations of the World Health Organiz…

AdultMaleGerontologyIndex of Orthodontic Treatment Needmedicine.medical_specialtyCross-sectional studyPopulationMEDLINESocial classEpidemiologyHumansMedicineYoung adulteducationGeneral DentistrySocioeconomic statusHealth Services Needs and Demandeducation.field_of_studybusiness.industry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCommunity and Preventive DentistryCross-Sectional StudiesOtorhinolaryngologySpainUNESCO::CIENCIAS MÉDICASFemaleResearch-ArticleSurgeryMalocclusionbusinessMedicina Oral Patología Oral y Cirugia Bucal
researchProduct

Clinical evaluation of a modified marginal sulcular incision technique in endodontic surgery

2009

The authors evaluated periodontal parameters following apical surgery using a new marginal sulcular incision. In 65 cases, surgical access was achieved by means of a sulcular incision technique without the involvement of the adjacent periodontia and the interproximal papillae and in 33 cases by means of a submarginal trapezoidal technique. Periodontal parameters (probing pocket depth, gingival recession, clinical attachment loss, and tooth mobility [periotest]) were recorded at baseline and after 6 months. Scar formation and the loss of papilla height were evaluated photographically. No significant changes in the attachment level and no loss of papilla height were found in either group. A s…

AdultMaleGingivaDentistryTooth mobilityCicatrixTooth Apexstomatognathic systemApical surgeryHumansMedicineGingival RecessionGeneral DentistryGingival recessionOrthodonticsbusiness.industryApicoectomyMiddle AgedSurgical accessMajor duodenal papillaEndodontic surgeryOtorhinolaryngologyClinical attachment lossFemaleSurgeryTooth MobilityOral Surgerymedicine.symptombusinessClinical evaluationOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
researchProduct