Search results for "Number"
showing 10 items of 3939 documents
Focal DNA Copy Number Changes in Neuroblastoma Target MYCN Regulated Genes
2013
Neuroblastoma is an embryonic tumor arising from immature sympathetic nervous system cells. Recurrent genomic alterations include MYCN and ALK amplification as well as recurrent patterns of gains and losses of whole or large partial chromosome segments. A recent whole genome sequencing effort yielded no frequently recurring mutations in genes other than those affecting ALK. However, the study further stresses the importance of DNA copy number alterations in this disease, in particular for genes implicated in neuritogenesis. Here we provide additional evidence for the importance of focal DNA copy number gains and losses, which are predominantly observed in MYCN amplified tumors. A focal 5 kb…
Enseñanza de las ciencias : revista de investigación y experiencias didácticas
2020
Nuestro objetivo en esta investigación es identificar las dificultades de aprendizaje que tienen los niños de 1.º a 3.º grado de educación primaria en la construcción de los números naturales. Tales dificultades no proceden de la enseñanza, sino de las propias matemáticas y para poder observar esas dificultades, es necesario reducir el problema a los elementos primitivos. Con los modelos teóricos locales como marco teórico y metodológico, se ha diseñado un modelo de enseñanza traduciendo el componente formal (modelo de J. Von Neumann) a una secuencia de actividades con el uso de material manipulativo. Se analiza la experiencia de enseñanza y en los resultados se destacan y explican las difi…
Benchmarking of strength models for unidirectional composites under longitudinal tension
2018
© 2018 Elsevier Ltd Several modelling approaches are available in the literature to predict longitudinal tensile failure of fibre-reinforced polymers. However, a systematic, blind and unbiased comparison between the predictions from the different models and against experimental data has never been performed. This paper presents a benchmarking exercise performed for three different models from the literature: (i) an analytical hierarchical scaling law for composite fibre bundles, (ii) direct numerical simulations of composite fibre bundles, and (iii) a multiscale finite-element simulation method. The results show that there are significant discrepancies between the predictions of the differe…
Expression of MAP1a and MAP1b in the ganglionic eminence and the internal capsule of the human fetal brain.
2001
The expression of microtubule-associated proteins 1a and 1b (MAP1a and 1b) were investigated in two transient structures, the ganglionic eminence (GE) being a prominent part of the telencephalic proliferative zone and the perireticular nucleus (PR) within the internal capsule (IC). Anti-MAP1a immunolabels PR neurons from 18 weeks of gestation (wg) onwards, whereas anti-MAP1b immunolabels long IC fibers between 18 and 22 wg. MAP1b is further present in thalamic fibers that seem to terminate at the medial margin of the GE, in a moderate number of cells of the GE and its medial extension, the gangliothalamic body (GTB). From 26 to 33 wg MAP1b is expressed in short fiber bundles of the IC, a fe…
Nitrous oxide fluxes from permafrost regions
2020
This dataset is a synthesis of published nitrous oxide (N2O) fluxes from permafrost-affected soils in Arctic, Antarctic, and Alpine permafrost regions. The data includes mean N2O flux rates measured under field (in situ) conditions and in intact plant-soil systems (mesocosms) under near-field conditions. The dataset further includes explanatory environmental parameters such as meteorological data, soil physical-chemical properties, as well as site and experimental information. Data has been synthesized from published studies (see 'Further details'), and in some cases the authors of published studies have been contacted for additional site-level information. The dataset includes studies publ…
Annihilators of tensor density modules
2007
Abstract We describe the two-sided ideals in the universal enveloping algebras of the Lie algebras of vector fields on the line and the circle which annihilate the tensor density modules. Both of these Lie algebras contain the projective subalgebra, a copy of sl 2 . The restrictions of the tensor density modules to this subalgebra are duals of Verma modules (of sl 2 ) for Vec ( R ) and principal series modules (of sl 2 ) for Vec ( S 1 ) . Thus our results are related to the well-known theorem of Duflo describing the annihilating ideals of Verma modules of reductive Lie algebras. We find that, in general, the annihilator of a tensor density module of Vec ( R ) or Vec ( S 1 ) is generated by …
Weyl Type Theorems for Left and Right Polaroid Operators
2010
A bounded operator defined on a Banach space is said to be polaroid if every isolated point of the spectrum is a pole of the resolvent. In this paper we consider the two related notions of left and right polaroid, and explore them together with the condition of being a-polaroid. Moreover, the equivalences of Weyl type theorems and generalized Weyl type theorems are investigated for left and a-polaroid operators. As a consequence, we obtain a general framework which allows us to derive in a unified way many recent results, concerning Weyl type theorems (generalized or not) for important classes of operators.
Volumetric properties, viscosities and refractive indices of binary liquid mixtures of tetrafluoroborate-based ionic liquids with methanol at several…
2015
Abstract Densities, speeds of sound, viscosities and refractive indices of two binary systems 1-butyl-3-methylimidazolium tetrafluoroborate [bmim][BF4] + methanol and 1-ethyl-3-methylimidazolium tetrafluoroborate [emim][BF4] + methanol, as well as of all pure components, have been measured covering the whole range of compositions at T = (278.15 to 318.15) K and p = 101 kPa. From this data, excess molar volumes, excess isentropic compressibilities, viscosity deviations and refractive index deviations were calculated and fitted to extended versions of the Redlich–Kister equation. Estimated coefficients of these equations taking into account the dependence on composition and temperature simult…
Zinc oxide application in the textile industry: surface tailoring and water barrier attributes as parameters with direct implication in comfort perfo…
2013
The present study focuses on surface tailoring and water barrier attributes of zinc oxide (ZnO)-polyester composite textile materials. The surface properties, such as surface topography and roughness, composite compositions as well as thermal stability of ZnO-100% polyester textile composite materials treated through a padding process with different concentrations of ZnO dispersions as active agent in water and methanol were studied. The results show that 3% ZnO-textile composite material have enhanced water barrier properties compared with the other compositions; a fact which promises improved properties in terms of comfort. ZnO modification of polyester surfaces leads to a dramatic decre…
DECORIN EFFECTS ON PROTEOMIC PROFILING OF BREAST CANCER CELLS: AN UPDATED STUDY
2015
The malignant carcinomas are characterized by several capabilities acquired by the neoplastic cells, among which the ability to invade the extracellular matrix (ECM) and to establish a crosstalk with several ECM components. Under this respect, the extracellular microenvironment is an entity extraordinarily rich of information with opposite signals. Our group has long undertaken the study of the effects of ECM molecules on the behavior of cancer cells in vitro. Among the studied molecules, the decorin was found to exert a non-permissive effect on the growth and motility of the transfected tumor cells. The decorin, belongs to the family of small leucine-rich proteoglycans (SLRP) and is involv…