Search results for "OCAI"
showing 10 items of 237 documents
Differential effects of MDMA and cocaine on inhibitory avoidance and object recognition tests in rodents.
2017
Introduction Drug addiction continues being a major public problem faced by modern societies with different social, health and legal consequences for the consumers. Consumption of psychostimulants, like cocaine or MDMA (known as ecstasy) are highly prevalent and cognitive and memory impairments have been related with the abuse of these drugs. Aim The aim of this work was to review the most important data of the literature in the last 10 years about the effects of cocaine and MDMA on inhibitory avoidance and object recognition tests in rodents. Development: The object recognition and the inhibitory avoidance tests are popular procedures used to assess different types of memory. We compare th…
Effect of cocaine and related drugs on the uptake of noradrenaline by heart and spleen
1961
Noradrenaline uptake by heart and spleen after intravenous infusion of noradrenaline was measured in the pithed rat. Cocaine, given before the infusion, inhibited the noradrenaline uptake in relation (a) to the dose administered and (b) to the amount of noradrenaline infused. There was an association between increase in the pressor response to a test dose of noradrenaline and inhibition of the uptake by the heart. Drugs related chemically to cocaine, such as alpha-cocaine, amethocaine, and atropine, did not alter the noradrenaline uptake or potentiate the blood pressure response to noradrenaline. The noradrenaline uptake by the heart was unchanged after dibenamine, but blocked by the dichlo…
Fast-Track Surgery and Early Rehabilitation for Total Hip Replacement in Hospital of Traumatology and Orthopaedics
2019
Abstract Due to an ageing population, the necessity for hip replacement has grown, and therefore, new options are being sought, such as the Fast-track principle, to improve patient condition, reduce their hospital stay and enhance the hospital’s ability to treat more patients. The aim of this study was to investigate the effects of same-day patient mobilisation on pain, side effects, complications, duration of hospital stay, and recovery after primary hip replacement, using intermediate-acting local anaesthetics in spinal anaesthesia (SA). A prospective, randomised study was conducted at the Hospital of Traumatology and Orthopaedics. Forty-six patients undergoing total hip replacement were …
Role of ozone Disc Nucleolysis in Herniated intervertebral Disc : The Indian experience [abstract]
2018
Aim: To study the role of ozone disc Nucleolysis in herniated intervertebral disc 
 Materials: We retrospectively analysed consecutives patients undergoing ozone disc nucleolysis. There were Total of 5265 patients with 2740 males and 2525 females .their Age was ranging from 17yrs to 84 years. Patients weight was ranging from 36 to 138 kilograms. All the patients had failed conservative management for at least 3weeks. 
 Methods: All the patients were clinically evaluated as per inclusion and exclusion criterions. Pre-treatment Visual Analogue scale (VAS)and Oswestry Disability Index (ODI).All the patients undergone Pre-treatments work up of MRI of the spine.256 patients were underg…
A prospective randomized clinical trial compared the effect of various types of local anesthetics cartridges on hypertensive patients during dental e…
2015
Objectives: To evaluate hemodynamic changes of blood pressure and heart rate on hypertensive patients undergoing tooth extraction using various types of local anesthesia (LA). Study Design: A prospective randomized clinical trial was conducted on 45 hypertensive patients who were divided equally into 3 parallel groups according to LA received. Group 1: Lidociane 2% with epinephrine 1: 80,000. Group 2: Prilocaine 3% with Felypressin 0.03 IU/ml. Group 3: Mepivacaine 3% plain. Inclusion criteria: hypertensive patients, under medical management with blood pressure ≤ 159/99. Exclusion criteria: Blood pressure ≥160 /100 and patients receiving β blockers. Negative aspiration was mandatory before t…
Neuroinflammatory and behavioral susceptibility profile of mice exposed to social stress towards cocaine effects.
2021
Using the social defeat (SD) model, numerous studies have shown that stressed mice display an enhanced response to the motivational effects of cocaine in the self-administration (SA) and conditioned-place preference (CPP) paradigms. However, not all subjects exposed to stress express its harmful effects. Some are particularly susceptible to the deleterious effects of repeated SD, while resilient mice successfully cope with stressful experiences and display adjusted psychological functioning after stress. Vulnerability to develop stress-related disorders, such as depression, has been linked to coping strategies and more recently to individual differences in the immune system. However, no stu…
Cannabidiol Treatment Might Promote Resilience to Cocaine and Methamphetamine Use Disorders: A Review of Possible Mechanisms
2019
Currently, there are no approved pharmacotherapies for addiction to cocaine and other psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a promising treatment for substance use disorders. In the present work, the authors describe the scarce preclinical and human research about the actions of CBD on the effects of stimulant drugs, mainly cocaine and methamphetamine (METH). Additionally, the possible mechanisms underlying the therapeutic potential of CBD on stimulant use disorders are reviewed. CBD has reversed toxicity and seizures induced by cocaine, behavioural sensitization induced by amphetamines, motivation to self-administer cocaine and METH, context- …
Enfance, logiques de la filiation et de la transmission dans l’œuvre de Rachid O.
2017
L’enfance apparaît chez Rachid O. comme une période à laquelle il accorde une grande attention dans son œuvre romanesque, mais aussi comme le pivot autour duquel tournent le questionnement sur son identité homosexuelle, ses rapports familiaux et son écriture. Cet article interroge la représentation de l’enfance et sa panoplie de constructions imaginaires, mais aussi les structures symboliques de la filiation et de la transmission, là où elles dévoilent le réel de l’écrivain et montrent l’enjeu de la jouissance.
La résilience en marche : Drââ, un projet franco-marocain d’observatoire territorial
2014
International audience
Organizācijas kultūras pilnveides iespējas Pumpuru vidusskolā
2022
Bakalaura darbā „Organizācijas kultūras pilnveides iespējas Pumpuru vidusskolā” autore Ieva Šleinere pēta Pumpuru vidusskolas organizācijas kultūru un sniedz priekšlikumus tās pilnveides iespējām. Darba mērķis ir pētīt organizācijas kultūru Pumpuru vidusskolā, izstrādāt priekšlikumus tās pilnveides iespējām. Pētījuma uzdevumi 1. analizēt zinātnisko literatūru par organizācijas kultūras nozīmi izglītības iestādē, 2. pētīt organizācijas kultūru Pumpuru vidusskolā, 3. analizēt gūtos rezultātus, izstrādājot secinājumus un ieteikumus organizācijas kultūras pilnveides iespējām Pumpuru vidusskolā. Bakalaura darbs sastāv no ievada, teorētiskās daļas, empīriskā daļas, secinājumiem, priekšlikumiem, l…