Search results for "OCR"

Homocisteína plasmática, Lp(a) y marcadores de estrés oxidativo en la vasculopatía periférica del paciente con diabetes tipo 2

2016

Resumen Objetivo Buscar nuevos factores biologicos como el estres oxidativo (EO) y su interaccion con los clasicos, edad, HbA1c, Lp(a) y homocisteina plasmatica asociados con la vasculopatia periferica (VP) del paciente con diabetes tipo 2 (DMT2). Sujetos y metodos Estudiamos 204 diabeticos tipo 2 seleccionados de forma consecutiva de un hospital de referencia y un hospital comarcal de nuestra comunidad autonoma en el periodo comprendido entre enero de 2009 a mayo de 2010. Se trato de un estudio transversal de caso (ITB   1,2. Los parametros clinicobiologicos fueron medidos por procedimientos estandarizados. Resultados Los sujetos fueron divididos en 2 grupos: con VP (ITB > 0,89) o sin VP (…

Il neonato che “sa di sale”

2021

Pseudohypoaldosteronism type 1 (PHA1) is a rare genetic disease due to the peripheral resistance to aldosterone. Clinical spectrum with neonatal onset includes salt loss, hyponatremia, hypochloraemia, hyperkalaemia, metabolic acidosis and increased plasmatic levels of aldosterone. Two forms of the disease - renal and systemic – have been described, which are genetically distinct and with wide clinical expressivity. The most severe generalized PHA1 is caused by mutations in the genes encoding for the subunits of the epithelial sodium channels (ENaC). The paper reports the case of a newborn of the first pregnancy of healthy and consanguineous Sicilian parents, with a clinical and hormonal pic…

Intergenerational differences in the body build of women

2019

Background: This study analyzed generational differences in body build of woman. Aim of the study: The aim of the study was to examine the intergenerational differences in the body build of women. Material and methods: 90 women (30 female physiotherapy students, their mothers and grandmothers) were examined. Their heights, weights, waist circumferences, and waist and hip circumferences were measured. Their Body mass index (BMI) and Waist to Hip Ratio (WHR) were calculated. Their frequency of underweight, overweight and obesity were estimated. WHO criteria were applied. The results were subjected to statistical analysis. Descriptive statistics were calculated. The Shapiro-Wilk test for testi…

Les tuteurs de résilience des enfants et adolescents vivant dans des camps à Port-au-Prince et dans les villes avoisinantes

2016

Resume Dans le contexte de reconstruction durable d’Haiti suite au seisme du 12 janvier 2010, cette recherche analyse les processus de resilience et createurs des enfants et adolescents haitiens. Elle examine notamment le role de la famille, de l’ecole, des institutions de soin, des croyances, des reseaux associatifs, de l’Etat et de la communaute internationale dans l’emergence de ces processus. Ces strates sont considerees comme des moyens humains susceptibles d’aider a l’elaboration des vecus difficiles et a la reconstruction des etayages, la recherche vise principalement a reperer les tuteurs de resilience aupres des enfants et adolescents haitiens vivant dans des camps de Port-au-Princ…

Corrigendum to “Management of undescended testes: European Association of Urology/European Society for Paediatric Urology Guidelines” [J Pediatr Urol…

2017

Qualité de l’évaluation de l’état nutritionnel et évaluation de l’observance des compléments nutritionnels oraux chez des patients hospitalisés au CH…

2018

Introduction et but de l’etude A l’hopital, la mise en place d’une complementation nutritionnelle orale (CNO) intervient lorsque les apports energetiques et/ou proteiques des patients ne sont pas atteints et que l’enrichissement de l’alimentation ne suffit pas selon les criteres specifiques de la HAS (2007). L’objectif ici est d’evaluer les pratiques professionnelles autour du suivi de l’etat nutritionnel des patients avant, pendant et apres leur hospitalisation et de faire l’etat des lieux de la consommation reelle de CNO et de leur representation par les patients. Materiel et methodes Une etude prospective a ete realisee dans les services d’endocrinologie et de chirurgie digestive. L’eval…

Système endocannabinoïde : effets sur le métabolisme glucidique, mais aussi lipidique

2016

Resume Le systeme endocannabinoide (SEC) est compose de recepteurs couples aux proteines G : Cannabinoid type 1-receptor (CB 1 -R) et Cannabinoid type 2-receptor (CB 2 -R), de leurs ligands endogenes (anandamide [AEA], et 2-acylglycerol [2-AG]), et des enzymes responsables de leur synthese et de leur degradation. Bien que les recepteurs CB 1 -R et CB 2 -R furent initialement decrits au niveau du systeme nerveux central, ils sont presents dans de nombreux tissus peripheriques, ou ils sont impliques dans le metabolisme, la croissance, et l’inflammation. Apres le retrait commercial du rimonabant, pour des effets secondaires psychiatriques, un agoniste inverse du recepteur CB 1 (CB 1 -R), desti…

Betulinic Acid Exerts Cytotoxic Activity Against Multidrug-Resistant Tumor Cells via Targeting Autocrine Motility Factor Receptor (AMFR).

2018

Betulinic acid (BetA) is a naturally occurring pentacyclic triterpene isolated from the outer bark of white-barked birch trees and many other medicinal plants. Here, we studied betulinic acid's cytotoxic activity against drug-resistant tumor cell lines. P-glycoprotein (MDR1/ABCB1) and BCRP (ABCG2) are known ATP-binding cassette (ABC) drug transporters that mediating MDR. ABCB5 is a close relative to ABCB1, which also mediates MDR. Constitutive activation of the EGF receptor is tightly linked to the development of chemotherapeutic resistance. BetA inhibited P-gp, BCRP, ABCB5 and mutation activated EGFR overexpressing cells with similar efficacy as their drug-sensitive parental counterparts. …

What are the determinants of adherence to the mediterranean diet?

2021

Current evidence suggests that adherence to traditional dietary patterns are slowly disappearing in favour of a globalised market, in which higher availability of processed, ready-to-use, energy-dense foods undermines the consumption of fresh, locally produced goods ... When exploring the nutritional quality of processed foods, excess content in added free sugars, saturated and hydrogenated fats, together with scarcity in fibre and vitamins, ...

2021

Proteins play a crucial role in metabolism, in maintaining fluid and acid-base balance and antibody synthesis. Dietary proteins are important nutrients and are classified into: 1) animal proteins (meat, fish, poultry, eggs and dairy), and, 2) plant proteins (legumes, nuts and soy). Dietary modification is one of the most important lifestyle changes that has been shown to significantly decrease the risk of cardiovascular (CV) disease (CVD) by attenuating related risk factors. The CVD burden is reduced by optimum diet through replacement of unprocessed meat with low saturated fat, animal proteins and plant proteins. In view of the available evidence, it has become acceptable to emphasize the …