Search results for "ODD"

What drives inhaler prescription for asthma patients? Results from a real-life retrospective analysis

2020

Abstract Background The choice of inhaler device for asthma patients depends upon multiple attributes. We investigated factors that may drive general practitioners (GPs) and respiratory specialists in the prescription of inhaler devices for asthma patients who initiated inhalation therapy. Methods We retrospectively analysed prescriptions by GPs and respiratory specialists to asthma patients commencing inhaled corticosteroid/long-acting β2-agonist combination therapy available as both pressurised metered-dose inhalers (pMDIs) and dry powder inhalers (DPIs). Patient characteristics were compared by device and multivariate analysis was used to model the likelihood of receiving a pMDI as oppos…

El tabaquismo pasivo en adultos

2002

Is an activity volume threshold really realistic for lung cancer resection?

2018

IF 1.804 (2017); International audience; Background:We analyzed volume as a continuous variable to estimate threshold, which is a methodology rarely seen in the literature. The objective of this work was to assess hospital volume for lung cancer (LC) surgery and to establish the associated threshold for acceptable in-hospital mortality (IHM). Data was obtained from the French national medico-administrative database.Methods:From January 2005 to December 2016, data from 108,571 patients operated for LC in France were collected from the national administrative database. To estimate the volume threshold, hierarchical logistic regression models were developed.Results:The crude IHM rate was 5.2% …

COVID-19 y tabaquismo: revisión sistemática y metaanálisis de la evidencia

2021

RESUMEN Objetivo: el objetivo del estudio ha sido responder a las siguientes preguntas: ¿Se asocia el consumo de tabaco en pacientes con Covid-19 con una progresión negativa y desenlace adverso de la enfermedad? y, ¿se asocia el consumo de tabaco, actual y pasado, a una mayor posibilidad de desarrollar COVID-19? Material y Métodos: Se realizó una revisión sistemática (RS) y metaanálisis (MA) de trabajos publicados previamente. La estrategia de búsqueda incluyó todos los descriptores conocidos sobre Covid-19 y tabaco y se realizó en diferentes bases de datos. Se utilizaron modelos estadísticos adecuados para abordar el tamaño del efecto en un metaanálisis: modelo de efectos aleatorios y de e…

On globally generated vector bundles on projective spaces II

2014

Extending a previous result of the authors, we classify globally generated vector bundles on projective spaces with first Chern class equal to three.

Chern classes of the moduli stack of curves

2005

Here we calculate the Chern classes of ${\bar {\mathcal M}}_{g,n}$, the moduli stack of stable n-pointed curves. In particular, we prove that such classes lie in the tautological ring.

Nonradial Hormander algebras of several variables and convolution operators

2001

A characterization of the closed principal ideals in nonradial Hormander algebras of holomorphic functions of several variables in terms of the behaviour of the generator is obtained. This result is applied to study the range of convolution operators and ultradifferential operators on spaces of quasianalytic functions of Beurling type. Contrary to what is known to happen in the case of non-quasianalytic functions, an ultradistribution on a space of quasianalytic functions is constructed such that the range of the operator does not contain the real analytic functions. Let u, v : R → R be continuous, non-negative and even functions which are increasing on the positive real numbers. We assume …

Closed star products and cyclic cohomology

1992

We define the notion of a closed star product. A (generalized) star product (deformation of the associative product of functions on a symplectic manifold W) is closed iff integration over W is a trace on the deformed algebra. We show that for these products the cyclic cohomology replaces the Hochschild cohomology in usual star products. We then define the character of a closed star product as the cohomology class (in the cyclic bicomplex) of a well-defined cocycle, and show that, in the case of pseudodifferential operators (standard ordering on the cotangent bundle to a compact Riemannian manifold), the character is defined and given by the Todd class, while in general it fails to satisfy t…

Severe asthma features in children: A case–control online survey

2016

Background Very few studies have explored the distinguishing features of severe asthma in childhood in Europe, and only one study was conducted in Southern Europe. The aim of this study was to provide a detailed characterization of children with severe asthma treated in specialized pediatric asthma centers across Italy. Methods We conducted a web-based data collection of family, environmental, clinical and laboratory characteristics of 41 patients aged 6–17 years with severe asthma, defined according to the recent guidelines of the European Respiratory Society and the American Thoracic Society, and 78 age-matched peers with non-severe persistent asthma. The patients have been enrolled from …

Occupational exposure to chlorinated and petroleum solvents and mycosis fungoides.

2013

OBJECTIVE: To evaluate the potential association between occupational exposure to chlorinated and petroleum solvents and mycosis fungoides (MF).METHODS: A questionnaire on lifetime job history was administered to 100 patients diagnosed with MF and 2846 controls. Odds ratios (ORs) were calculated as the measure of the association between exposure to each specific solvent and MF.RESULTS: In the total sample and in men, cases and controls did not differ in relation to exposure to any of the solvents studied. In women, an association with MF was seen for the highest level of estimated exposure to perchloroethylene (OR = 11.38; 95% confidence interval: 1.04 to 124.85) and for exposure less than …