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RESEARCH PRODUCT

Occupational exposure to chlorinated and petroleum solvents and mycosis fungoides.

Wolfgang AhrensAgustín Llopis-gonzálezLinda KaerlevJuan José AurrekoetxeaLennart HardellDiane CyrAndreas StangFranco MerlettiJoelle FevotteGiuseppe GoriniMaría Morales-suárez-varelaSara VilleneuvePreben JohansenJørn OlsenPascal GuénelGun Wingren

subject

QuestionnairesAdultMalemedicine.medical_specialtyTetrachloroethyleneSkin NeoplasmsMedizincomplex mixturesKeroseneMycosis FungoidesSex FactorsOccupational ExposureSurveys and Questionnairespolycyclic compoundsmedicineHydrocarbons ChlorinatedOdds RatioHumansAgedMycosis fungoidesbusiness.industryPublic Health Environmental and Occupational HealthMiddle Agedmedicine.diseaseDermatologyPetroleumCase-Control StudiesSolventsFemaleOccupational exposurebusinessFuel Oils

description

OBJECTIVE: To evaluate the potential association between occupational exposure to chlorinated and petroleum solvents and mycosis fungoides (MF).METHODS: A questionnaire on lifetime job history was administered to 100 patients diagnosed with MF and 2846 controls. Odds ratios (ORs) were calculated as the measure of the association between exposure to each specific solvent and MF.RESULTS: In the total sample and in men, cases and controls did not differ in relation to exposure to any of the solvents studied. In women, an association with MF was seen for the highest level of estimated exposure to perchloroethylene (OR = 11.38; 95% confidence interval: 1.04 to 124.85) and for exposure less than the median to kerosene/fuel/gasoil (OR = 8.53; 95% confidence interval: 1.11 to 65.62).CONCLUSIONS: These results do not provide conclusive evidence that exposure to solvents may increase risk of MF because they were not found in men.

yearjournalcountryeditionlanguage
2013-08-01Journal of occupational and environmental medicine
10.1097/jom.0b013e3182941a1chttps://pubmed.ncbi.nlm.nih.gov/23887697