0000000000243556

AUTHOR

Giuseppe Gorini

0000-0002-1413-5948

showing 11 related works from this author

Global, regional, and national burden of diseases and injuries for adults 70 years and older:systematic analysis for the Global Burden of Disease 201…

2022

AbstractObjectivesTo use data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) to estimate mortality and disability trends for the population aged ≥70 and evaluate patterns in causes of death, disability, and risk factors.DesignSystematic analysis.SettingParticipants were aged ≥70 from 204 countries and territories, 1990-2019.Main outcomes measuresYears of life lost, years lived with disability, disability adjusted life years, life expectancy at age 70 (LE-70), healthy life expectancy at age 70 (HALE-70), proportion of years in ill health at age 70 (PYIH-70), risk factors, and data coverage index were estimated based on standardised GBD methods.ResultsGlo…

RiskMale610 Medicine & healthCare1117 Public Health and Health ServicesGlobal Burden of DiseaseDisability EvaluationLife ExpectancyCost of IllnessDeclineRisk FactorsGeneral & Internal MedicineHumansObesityMortality610 Medicine & healthAgedAged 80 and overPublic Health Global Health Social Medicine and Epidemiology1103 Clinical SciencesGeneral MedicineMortality/trends3142 Public health care science environmental and occupational healthWounds and Injuries/epidemiologyFolkhälsovetenskap global hälsa socialmedicin och epidemiologiHealthWounds and InjuriesFemaleMorbidity
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Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study…

2022

Funding: Bill & Melinda Gates Foundation. Background: The global burden of lower respiratory infections (LRIs) and corresponding risk factors in children older than 5 years and adults has not been studied as comprehensively as it has been in children younger than 5 years. We assessed the burden and trends of LRIs and risk factors across all age groups by sex, for 204 countries and territories.  Methods: In this analysis of data for the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we used clinician-diagnosed pneumonia or bronchiolitis as our case definition for LRIs. We included International Classification of Diseases 9th edition codes 079.6, 466–469, 470.0, 480–4…

AdultMaleGlobal HealthTimeGlobal Burden of DiseaseSDG 3 - Good Health and Well-beingRisk FactorsRA0421RA0421 Public health. Hygiene. Preventive MedicineHumansAmbient air-qualityChildRespiratory Tract InfectionsAgedAged 80 and overMCCSex CharacteristicsMalnutritionPyridinolcarbamateBayes Theorem3rd-DAS3142 Public health care science environmental and occupational healthInfectious Diseases3121 General medicine internal medicine and other clinical medicineChild PreschoolFemaleParticulate MatterQuality-Adjusted Life YearsCovid-19LRI
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Neutron-induced soft errors in advanced Flash memories

2008

Atmospheric neutrons are a known source of Soft Errors (SE), in static and dynamic CMOS memories. This paper shows for the first time that atmospheric neutrons are able to induce SE in Flash memories as well. Detailed experimental results provide an explanation linking the Floating Gate (FG) cell SE rate to the physics of the neutron-matter interaction. The neutron sensitivity is expected to increase with the number of bits per cell and the reduction of the feature size, but the SE issue is within the limit of current ECC capabilities and will remain so in the foreseeable future.

PhysicsAstrophysics::High Energy Astrophysical PhenomenaHardware_PERFORMANCEANDRELIABILITYFlash memorySEESettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Computational physicsSettore FIS/03 - Fisica della MateriaReduction (complexity)Flash (photography)CMOSLimit (music)Electronic engineeringNeutronSensitivity (control systems)Error detection and correctionneutron irradiationSEE neutron irradiation
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Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study …

2020

Publisher's version (útgefin grein)

MaleLife expectancyDisability-Adjusted Life YearDiseasesDiseasecommunicable diseasesystematic analysisGlobal Burden of Disease0302 clinical medicine80 and overMedicine10. No inequalityChild11 Medical and Health SciencesinjuriesAged 80 and overeducation.field_of_studySjúkdómarDEMENTIAFALLSGeneral MedicineForvarnir3. Good healthChild PreschoolHumanGBDPopulation health03 medical and health sciencesSDG 3 - Good Health and Well-beingHumansGlobal Burden of Disease StudyeducationAgedSpatial AnalysisGlobal burdenDisabilityPreventionDISABILITYInfantSpatial AnalysiMortality rateGlobal Burden of Disease Diseases Injuries Systematic analysisPREVENTIONYears of potential life lostRisk factorsDisease studyGBD; communicable disease; injuries;ITC-ISI-JOURNAL-ARTICLELife expectancyRISK-FACTORSClinical MedicineRADemographyFötlunDánartíðniÁhættuþættir030204 cardiovascular system & hematologyRisk FactorsCause of DeathGlobal health030212 general & internal medicineMortality ratePopulation health1. No povertyDisability-Adjusted Life YearsPublic Health Global Health Social Medicine and EpidemiologyMiddle Aged3142 Public health care science environmental and occupational healthAdolescent; Adult; Age Distribution; Aged; Aged 80 and over; Cause of Death; Child; Child Preschool; Disability-Adjusted Life Years; Female; Global Burden of Disease; Humans; Infant; Infant Newborn; Male; Middle Aged; Risk Factors; Spatial Analysis; Young Adult/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingLýðheilsaFemaleCLINICAL-TRIALSAdultAdolescentPopulationGlobal healthSettore MED/01 - Statistica MedicadiseasesITC-HYBRIDYoung AdultHeilbrigðisvísindiAge DistributionGeneral & Internal MedicineMortalityPreschoolDisease burdenbusiness.industryRisk FactorKlinisk medicinInfant NewbornNewborn//purl.org/pe-repo/ocde/ford#3.02.00 [https]Folkhälsovetenskap global hälsa socialmedicin och epidemiologiÁverkarSystematic analysisNAbusiness
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Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

2020

Background Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a standardised and comprehensive assessment of the magnitude of risk factor exposure, relative risk, and attributable burden of disease. Methods GBD 2019 estimated attributable mortality, years of life lost (YLLs), years of life lived with disability (YLDs), and disability-adjusted life-years (DALYs) for 87 risk factors and combinations of risk factors, at the…

MaleNutritional SciencesSpecific riskContaminación del Aire Interior030204 cardiovascular system & hematologySocioeconomic Factorsystematic analysisGlobal HealthBody Mass IndexGlobal Burden of DiseaseHealth Risk BehaviorHealth Risk BehaviorsDisease studies0302 clinical medicineRisk FactorsMETABOLIC RISKS030212 general & internal medicine11 Medical and Health SciencesFactores de Riesgo2. Zero hungereducation.field_of_studyPublic healthInjuriesPublic Health Global Health Social Medicine and EpidemiologyGeneral MedicineGBD; risck factors; attributable burden of disease;3142 Public health care science environmental and occupational health3. Good healthRelative riskEnvironmental healthHealthHypertension/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingGlobal Burden of Diseases Injuries Risk FactorsA990 Medicine and Dentistry not elsewhere classifiedFemaleLeading risk factorsGlobal Health MetricsCohort studyHumanmedicine.medical_specialtySubstance-Related DisordersPopulationUNITED-STATESRisk AssessmentDIETITC-HYBRID03 medical and health sciencesLife ExpectancyUNITED-STATES; MORTALITY; DISABILITY; POLLUTION; CLUSTERS; DIETSDG 3 - Good Health and Well-beingPOLLUTIONGeneral & Internal MedicineEnvironmental healthmedicineHumansGlobal Burden of Disease StudyRisk factoreducationGlobal burdenbusiness.industryPublic healthRisk FactorMORTALITYDISABILITYMalnutritionKlinisk medicinGlobal Burden of DiseasesEnvironmental Exposuremedicine.diseaseEnfermedades//purl.org/pe-repo/ocde/ford#3.02.00 [https]MalnutritionFolkhälsovetenskap global hälsa socialmedicin och epidemiologiYears of potential life lostSocioeconomic FactorsRisk factorsDisease studyRelative riskHyperglycemiaITC-ISI-JOURNAL-ARTICLENAClinical MedicinebusinessCLUSTERSRA
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The global burden of cancer attributable to risk factors, 2010–19 : A systematic analysis for the Global Burden of Disease Study 2019

2022

Background: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods: The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 20…

MaleDEATHSDALY cancer risk factorsMedizinsystematic analysisGlobal HealthRisk AssessmentCancer preventionGlobal Burden of DiseaseRC0254Risk-attributable cancer deathsSDG 3 - Good Health and Well-beingRA0421Risk FactorsRA0421 Public health. Hygiene. Preventive MedicineQuality-Adjusted Life YearNeoplasmscancerHumansGlobal Burden of Disease StudyUKMedicine(all)MCCRC0254 Neoplasms. Tumors. Oncology (including Cancer)Risk FactorSmokingCOVID-193rd-DASGeneral MedicineDisability-adjusted life-yearsSOCIAL DETERMINANTSRisk assessmentsrisk factorCardiovascular and Metabolic Diseases3121 General medicine internal medicine and other clinical medicineOBESITYCancer burden/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingNeoplasmFemaleLIFE-STYLEQuality-Adjusted Life YearsHEALTHRAHumanRC
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Burden of non-communicable diseases among adolescents aged 10-24 years in the EU, 1990-2019: a systematic analysis of the Global Burden of Diseases S…

2022

Background: Disability and mortality burden of non-communicable diseases (NCDs) have risen worldwide; however, the NCD burden among adolescents remains poorly described in the EU. Methods: Estimates were retrieved from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Causes of NCDs were analysed at three different levels of the GBD 2019 hierarchy, for which mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) were extracted. Estimates, with the 95% uncertainty intervals (UI), were retrieved for EU Member States from 1990 to 2019, three age subgroups (10–14 years, 15–19 years, and 20–…

Malemortality burdenAdolescentRJRJ101CareGlobal Burden of DiseaseLife ExpectancyRJ101 Child Health. Child health servicesSDG 3 - Good Health and Well-beingRA04213123 Gynaecology and paediatricsRisk FactorsRA0421 Public health. Hygiene. Preventive MedicineDevelopmental and Educational PsychologyHumansDisabled PersonsNoncommunicable DiseasesFutureDeterminantsMCCDisabilityPublic Health Global Health Social Medicine and EpidemiologyBurden of non-communicable diseases among adolescents aged 10–24 years in the EU 1990–2019: a systematic analysis of the Global Burden of Diseases Study 20193rd-DASDisability; mortality burdenFolkhälsovetenskap global hälsa socialmedicin och epidemiologin/aHealthPediatrics Perinatology and Child HealthFemaleRA
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Mapping 123 million neonatal, infant and child deaths between 2000 and 2017

2019

Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2—to end preventable child deaths by 2030—we need consistently estimated data at the subnational level regarding child mortality rates and trends. Here we quantified, for the period 2000–2017, the subnational variation in mortality rates and number of deaths of neonates, infants and children under 5 years of age within 99 low- and middle-income countries using a geostatistical survival model. We estimated that 32% of children under 5 in these countries lived in districts that had attained ra…

SurvivalRJ101Mortalidad InfantilHBUNDER-5 MORTALITYGlobal HealthPediatrics0302 clinical medicine3123 Gynaecology and paediatricsChild deathInfant MortalityEpidemiologyGlobal healthMiddle income countryNacimiento vivo030212 general & internal medicine10. No inequalityChildPOPULATIONDeveloping worldeducation.field_of_studyPublic healthMultidisciplinaryGeographyMortality ratewa_9001. No povertyRSUCCESSPediatrikA900 Others in Medicine and Dentistry3142 Public health care science environmental and occupational health3. Good healthChild MortalityDeath childrenVACCINATIONHEALTHws_100INTERVENTIONSAFRICAmedicine.medical_specialtyUnited NationsGeneral Science & Technology030231 tropical medicinePopulationDeveloping countryArticleHealthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]ITC-HYBRID03 medical and health sciencesAll institutes and research themes of the Radboud University Medical CenterSocial JusticeRecién nacidoNeonatal deathsmedicineSYSTEMATIC ANALYSISOrganizational ObjectivesHumanseducationDeveloping Countriesbusiness.industryPublic healthInfant NewbornInfantCIVIL REGISTRATIONPaediatricsChild survivalNewbornPREVENTIONMortality rateInfant mortalitywa_320ws_200Child mortalitySocioeconomic FactorsITC-ISI-JOURNAL-ARTICLEHuman medicinePaediatrics Public health Developing worldbusinessDemography
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Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease St…

2022

Correction to Lancet Gastroenterol Hepatol 2022; 7: 627-47. Lancet Gastroenterol Hepatol. 2022 Aug;7(8):704. doi: 10.1016/S2468-1253(22)00210-2. PMID: 35809605. Background: Colorectal cancer is the third leading cause of cancer deaths worldwide. Given the recent increasing trends in colorectal cancer incidence globally, up-to-date information on the colorectal cancer burden could guide screening, early detection, and treatment strategies, and help effectively allocate resources. We examined the temporal patterns of the global, regional, and national burden of colorectal cancer and its risk factors in 204 countries and territories across the past three decades. Methods: Estimates of incidenc…

AdultMED/42 - IGIENE GENERALE E APPLICATAIMPACTcolorectal cancerColorectal NeoplasmGBD 2019 Colorectal Cancer CollaboratorsHEREDITARYGlobal Burden of DiseaseCancer screeningDISPARITIESSDG 3 - Good Health and Well-beingCancer treatment strategiesRisk FactorsQuality-Adjusted Life YearCOLONGlobal studiesDALY GBD colorectal cancerrisk factorsHumansGlobal Burden of Disease StudyEarly Detection of CancerHepatologyMORTALITYGastroenterologyCancer incidence ratesMiddle AgedCancer burdenSURVIVAL/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSEXGENDERQuality-Adjusted Life YearsColorectal NeoplasmsHumanThe Lancet Gastroenterology & Hepatology
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Occupational exposure to chlorinated and petroleum solvents and mycosis fungoides.

2013

OBJECTIVE: To evaluate the potential association between occupational exposure to chlorinated and petroleum solvents and mycosis fungoides (MF).METHODS: A questionnaire on lifetime job history was administered to 100 patients diagnosed with MF and 2846 controls. Odds ratios (ORs) were calculated as the measure of the association between exposure to each specific solvent and MF.RESULTS: In the total sample and in men, cases and controls did not differ in relation to exposure to any of the solvents studied. In women, an association with MF was seen for the highest level of estimated exposure to perchloroethylene (OR = 11.38; 95% confidence interval: 1.04 to 124.85) and for exposure less than …

QuestionnairesAdultMalemedicine.medical_specialtyTetrachloroethyleneSkin NeoplasmsMedizincomplex mixturesKeroseneMycosis FungoidesSex FactorsOccupational ExposureSurveys and Questionnairespolycyclic compoundsmedicineHydrocarbons ChlorinatedOdds RatioHumansAgedMycosis fungoidesbusiness.industryPublic Health Environmental and Occupational HealthMiddle Agedmedicine.diseaseDermatologyPetroleumCase-Control StudiesSolventsFemaleOccupational exposurebusinessFuel OilsJournal of occupational and environmental medicine
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Overview of the JET results in support to ITER

2017

The 2014–2016 JET results are reviewed in the light of their significance for optimising the ITER research plan for the active and non-active operation. More than 60 h of plasma operation with ITER first wall materials successfully took place since its installation in 2011. New multi-machine scaling of the type I-ELM divertor energy flux density to ITER is supported by first principle modelling. ITER relevant disruption experiments and first principle modelling are reported with a set of three disruption mitigation valves mimicking the ITER setup. Insights of the L–H power threshold in Deuterium and Hydrogen are given, stressing the importance of the magnetic configurations and the recent m…

Technologyfusion:Física [Ciências exactas e naturais]TokamakNuclear engineeringDIAGNOSTICS01 natural sciencesILW010305 fluids & plasmaslaw.inventionIlw[SPI.MECA.MEFL]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Fluids mechanics [physics.class-ph]PlasmaH-Mode PlasmaslawITERDisruption PredictionCOLLISIONALITYEDGE LOCALIZED MODESDiagnosticsOperationfusion; ITER; JET; plasma; Nuclear and High Energy Physics; Condensed Matter PhysicsPhysicsJet (fluid)JET plasma fusion ITERDivertorSettore FIS/01 - Fisica SperimentaleCondensed Matter PhysicsFusion Plasma and Space PhysicsDENSITY PEAKINGCarbon WallH-MODE PLASMAS[ SPI.MECA.MEFL ] Engineering Sciences [physics]/Mechanics [physics.med-ph]/Fluids mechanics [physics.class-ph]Density PeakingNuclear and High Energy PhysicsNeutron transportFacing ComponentsCollisionality114 Physical sciencesFísica FísicaNuclear physics:Physical sciences [Natural sciences]Fusion plasma och rymdfysikPedestal0103 physical sciencesNuclear fusionddc:530Neutron010306 general physicsFusionplasmaPhysics Physical sciencesNuclear and High Energy PhysicEdge Localized ModesQC717:Física [Àrees temàtiques de la UPC]Reactors de fusióFísicaFACING COMPONENTSFusion reactorsJetJETCARBON WALLDISRUPTION PREDICTIONOPERATIONddc:600Collisionality
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