Search results for "OIT"
showing 10 items of 9012 documents
Congenital primary hypothyroidism with subsequent adenomatous goiter in a Turkish patient caused by a homozygous 10-bp deletion in the thyroid peroxi…
2006
Summary Objective Congenital primary hypothyroidism occurs in 1 of 4000 births. Whereas the majority of the cases are due to developmental defects of the thyroid gland, 20% carry a defect in thyroid hormonogenesis. We report a Turkish boy who had goitrous hypothyroidism due to a mutation in the thyroid peroxidase (TPO) gene. Design The TPO gene was sequenced directly from genomic DNA and cDNA which was transcribed from three RNA samples harvested from different parts of the patient's excised thyroid gland. Patient The boy was thyroidectomized because of continuing growth of his thyroid gland and development of multiple nodes suspected of malignancy by ultrasound examination. Histopatholo…
L'administrateur référent : un nouveau personnage au théâtre du conseil
2013
International audience
Cautionnement. Exceptions opposables par la caution, Inobservation de l'obligation d'information annuelle du banquier (oui), Extinction de la créance…
1998
International audience; (Com. 22 avr. 1997, consorts Dame c/ Crédit agricole mutuel de la Manche et autres ; Com. 20 mai 1997, Mene c/ Caisse régionale de Crédit agricole mutuel du Sud-Ouest et Billioud, ès qual. ; Com. 28 janv. 1997, BNP c/ M. Astarita et autre)
A scoping review on interventions to promote physical activity among adults with disabilities
2018
Abstract Background Despite the strong evidence that physical activity (PA) is a key determinant of health, there is limited knowledge on the content and outcomes of PA promotion interventions among individuals with disabilities. Objective To conduct a scoping review in order to examine the published literature on PA promotion interventions among adults with disabilities. Methods A scoping review following the methodological framework provided by Arksey and O'Malley used electronic databases (MEDLINE, PsycINFO, and CINAHL), reference lists, and journals to locate studies. Inclusion criteria were based on study aim, outcome measures, and a disability definition by the WHO International Class…
Effect of fall direction on the lower hip fracture risk in athletes with different loading histories : A finite element modeling study in multiple si…
2022
Physical loading makes bones stronger through structural adaptation. Finding effective modes of exercise to improve proximal femur strength has the potential to decrease hip fracture risk. Previous proximal femur finite element (FE) modeling studies have indicated that the loading history comprising impact exercises is associated with substantially higher fracture load. However, those results were limited only to one specified fall direction. It remains thus unclear whether exercise-induced higher fracture load depends on the fall direction. To address this, using magnetic resonance images of proximal femora from 91 female athletes (mean age 24.7 years with >8 years competitive career) and …
Does recovery buffer against emotional labor in terms of motivational outcomes at work? Analyzing age differences among Finnish health care professio…
2017
• Emotional labor is a common job stressor among health care professionals and therefore more research evidence is needed concerning its buffers.
Constraints representing a meta-stable régime facilitate exploration during practice and transfer of learning in a complex multi-articular task
2018
Previous investigations have shown that inducing meta-stability\ud in behavior can be achieved by overlapping affordances through constraint\ud manipulation, allowing cooperative and competitive tendencies to\ud functionally coexist. The purpose of this paper was to test a number of\ud conditions applying these design principles on performance during skills\ud practice and transfer. Of additional interest, was whether the existing\ud skill level interacted with the environmental properties of the\ud experimental tasks (varying indoor climbing routes). Two skill groups\ud practised on three routes per session over four separate sessions. At the\ud end of the final session, climbers undertook…
Enhanced rehabilitation guidance after arthroscopic capsulolabral repair of the shoulder : a randomized controlled trial
2020
Objective: To compare the effects of a 12-month home-based exercise program to usual care in patients after arthroscopic capsulolabral repair of the shoulder. Design: Randomized controlled trial. Setting: Outpatient physical and rehabilitation medicine clinic. Subjects: Forty-five patients (mean age: 35 years; standard deviation (SD): 10 years) who underwent arthroscopic capsulolabral repair due to labral lesion were randomized into an exercise group (EG) or a control group (CG). Intervention: The EG received a 12-month home-based additional exercise program with four physiotherapy follow-up visits, while the CG received standard postoperative exercise instructions. Main measures: Self-repo…
Stimulatory TSH-Receptor Antibodies and Oxidative Stress in Graves Disease
2018
CONTEXT: We hypothesized that TSH-receptor (TSHR) stimulating antibodies (TSAbs) are involved in oxidative stress mechanisms in patients with Graves disease (GD). METHODS: Nicotinamide adenine dinucleotide phosphate oxidase, isoform 2 (NOX2); oxidative parameters; and oxidative burst were measured in serum, urine, and whole blood from patients with GD and control subjects. Superoxide production was investigated in human embryonic kidney (HEK)-293 cells stably overexpressing the TSHR. Lipid peroxidation was determined by immunodot-blot analysis for protein-bound 4-hydroxy-2-nonenal (4-HNE) in human primary thyrocytes and HEK-293–TSHR cells. RESULTS: Serum NOX2 levels were markedly higher in …
Microdialysis-Assessed Exercised Muscle Reveals Localized and Differential IGFBP Responses to Unilateral Stretch Shortening Cycle Exercise
2020
Microdialysis allows for a preview into local muscle metabolism and can provide physiological insight that blood measurements cannot. Purpose: To examine the potential differential IGF-I system regulation in interstitial fluid during unilateral stretch shortening cycle exercise. Methods: 10 men (26 ± 7 year) performed unilateral jumping [stretch shortening cycle (SSC) exercise at 50% of optimal jump height] until volitional fatigue on a sled apparatus. Biological sampling took place using a catheter inserted into an antecubital vein (serum), and 100 kDa microdialysis probes inserted into the thigh muscle of each exercise/control leg (dialysate). Serum was drawn before (Pre; −3 h) and after …