Search results for "OLDER"

showing 10 items of 1264 documents

Influence of segmental chromosome abnormalities on survival in children over the age of 12 months with unresectable localised peripheral neuroblastic…

2014

Background: The prognostic impact of segmental chromosome alterations (SCAs) in children older than 1 year, diagnosed with localised unresectable neuroblastoma (NB) without MYCN amplification enrolled in the European Unresectable Neuroblastoma (EUNB) protocol is still to be clarified, while, for other group of patients, the presence of SCAs is associated with poor prognosis. Methods: To understand the role of SCAs we performed multilocus/pangenomic analysis of 98 tumour samples from patients enrolled in the EUNB protocol. Results: Age at diagnosis was categorised into two groups using 18 months as the age cutoff. Significant difference in the presence of SCAs was seen in tumours of patients…

Cancer Researchmedicine.medical_specialtyPathologyMYCN AmplificationKaplan-Meier EstimateunresectableGastroenterologyDisease-Free Survivalsegmental chromosome alterationsNeuroblastomaneuroblastomaDDX1FISHaCGHOlder patientsPeripheral Nervous System NeoplasmsInternal medicineNeuroblastomaMYCNmedicineHumansMultiplex ligation-dependent probe amplificationGainChromosome AberrationsOncogene ProteinsComparative Genomic HybridizationN-Myc Proto-Oncogene Proteinbusiness.industrySignificant differenceGene AmplificationSegmental Chromosome abnormalitiesInfantNuclear ProteinsChromosomePrognosislocalisedmedicine.diseaseDoenças GenéticasMLPA3. Good healthPeripheralOncologyMycn amplificationClinical StudyHistopathologybusinessBritish Journal of Cancer
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Self-efficacy and perceived control in the prevention of cardiovascular disease

2010

Desde la Teoría de Acción Planeada (TAP), el objetivo de este trabajo es analizar si la autoeficacia y la percepción de control presentan diferencias predictivas sobre la intención y las conductas preventivas de la enfermedad cardiovascular. La muestra estuvo compuesta por 359 sujetos. Los datos han sido analizados empleando el paquete estadístico EQS 6.1. Los resultados muestran que la autoeficacia influye positiva y significativamente sobre la intención y sobre la conducta, mientras que la percepción de control influye negativa y significativamente sobre la intención de conducta, pero no sobre la conducta preventiva. Este trabajo ha mostrado la conveniencia de distinguir entre autoeficaci…

Cardiovascular system--DiseasesControl (Psychology)PLANNED BEHAVIOREnfermedad cardiovascularPhysical activityEXERCISEDETERMINANTSPREDICTIVE-VALIDITYPerceived ControlControl (Psicologia)Cardiovascular DiseaseSistema cardiovascular--MalaltiesPercepción de controlPerceived controlOLDER-ADULTSGeneral PsychologyDescriptive Study Using SurveysCONDOM USEAdaptació (Psicologia)PreventionPerceived controlINTENTIONCardiovascular diseaseSOUTH-AFRICAAdjustment (Psychology)PHYSICAL-ACTIVITYPrevenciónEstudio descriptivo mediante encuestaDescriptive study using surveysSelf-EfficacyREASONED ACTIONSelf-efficacyPsychologyHumanitiesUniversitas Psychologica
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A microscopic approach to Casimir forces between metal bodies

2014

We consider the Casimir interaction between macroscopic metallic objects in terms of the dispersion interactions (Casimir-Polder and van der Waals) between their constituents. Expressions for two- and three-body dispersion interactions between the microscopic parts of a metal are obtained, both in the retarded and non-retarded limits. They are then used to evaluate two- and three-body contributions of the Casimir force between two flat ideal metallic slabs. Our results show the non-applicability of the Hamaker approximation in this geometry. It is further seen that the three-body contributions give an overall repulsive contribution to the force, which is of the same order of magnitude as th…

Casimir effectVacuum fluctuationsCasimir-Polder force
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Dynamical Casimir-Polder forces between an atom and a conducting wall

2008

Casimir-Polder forces. Vacuum fluctuations.
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Electromagnetic field fluctuations near a dielectric half-space and appearance of surface divergences in the ideal conductor limit

2012

The electromagnetic field fluctuations in the vacuum state are considered in the region external to a half-space filled with a homogeneous non-dissipative dielectric. We discuss the appropriate limits to a real and an ideal metal, focusing on the renormalized field fluctuations (equivalent to energy densities) in the proximity of the dielectric-vacuum interface. We show that, whereas in presence of a real conductor the renormalized field fluctuations are finite in any point of space, surface divergences appear at the interface in the ideal conductor limit. The main features of such divergences are discussed in detail. We point out that the behavior of field fluctuations close to the interfa…

Casimir-Polder interactions.Quantum fluctuationVacuum fluctuationSettore FIS/03 - Fisica Della Materia
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What are the effects of the aging of the neuromuscular system on postural stability?

2015

International audience; Aging is frequently associated with a decreased postural stability, essentially after 60 years, leading to an increased risk of falling. In this article we propose to highlight the influence of the aging of the neuromuscular system on postural stability when standing upright. To maintain balance while standing upright, human needs to control the activity of ankle muscles and particularly the plantar flexors. During the aging process, the performance of these muscles are strongly altered. It is commonly observed large deficits in elderly people with history of falls. Some authors reported an inverse correlation between the amplitude of postural sway and the capacity o…

Central Nervous SystemMale030506 rehabilitationnursing-home residents0302 clinical medicineelderly adultsElderly peopleolder-adultsrisk-factorsPostural BalanceAged 80 and overNeuropsychology and Physiological Psychologymedicine.anatomical_structurePostural stabilitytriceps suraeFemale[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]0305 other medical scienceFalling (sensation)medicine.medical_specialtysoleus h-reflexfallmechanical-propertieshuman skeletal-musclePhysical exercise03 medical and health sciencesPhysical medicine and rehabilitationankle muscleslength-tension relationshipmedicineHumansInverse correlationMuscle SkeletalBiological PsychiatryBalance (ability)Agedbusiness.industryagingage-related-changesbalance controlIncreased riskpostural stability[ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Physical therapyAccidental FallsNeurology (clinical)Geriatrics and GerontologyAnklebusiness030217 neurology & neurosurgery
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2019

Abstract Background In old age, decline in functioning may cause changes in walking ability. Our aim was to study whether older people who report adaptive, maladaptive, or no walking modifications differ in outdoor mobility. Methods Community-dwelling people aged 75–90 years (N = 848) were interviewed at baseline, of whom 761 participated in the 2-year follow-up. Walking modifications were assessed by asking the participants whether they had modified their way of walking 2 km due to their health. Based on the responses, three categories were formed: no walking modifications (reference), adaptive (eg, walking more slowly, using an aid), and maladaptive walking modifications (reduced frequenc…

Change over timeAging030505 public healthbusiness.industryPhysical activityOdds ratioPhysical functionConfidence interval03 medical and health sciences0302 clinical medicineMedicine030212 general & internal medicineGeriatrics and Gerontology0305 other medical scienceOlder peoplebusinessDemographyThe Journals of Gerontology Series A: Biological Sciences and Medical Sciences
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Bedside chest ultrasound to distinguish heart failure from pneumonia‐related dyspnoea in older COVID‐19 patients

2020

Abstract Aims In the older population, acute heart failure is a frequent, life‐threatening complication of COVID‐19 that requires urgent specific care. We aimed to explore the impact of point‐of‐care chest ultrasound (CUS) use in older bedridden inpatients during the COVID‐19 pandemic as a tool to distinguish between cardiogenic pulmonary oedema and isolated viral pneumonia‐related dyspnoea. Methods and results This prospective series included 16 patients aged 75 or older, hospitalized for acute dyspnoea in an acute geriatric unit of a university hospital and testing positive for a SARS‐Cov2 infection. We collected demographic characteristics, medical history, biological screening, clinical…

Chest ultrasoundmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Short CommunicationShort CommunicationsContext (language use)Heart failurePoint‐of‐care ultrasound030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineOlder patientsCOVID‐19Internal medicineDyspnoeamedicineDiseases of the circulatory (Cardiovascular) systemMedical history030212 general & internal medicineAgedbusiness.industryPneumoniamedicine.diseasePneumoniaRC666-701Heart failureCardiology and Cardiovascular MedicinebusinessComplicationESC Heart Failure
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Associations Between Built Environment Characteristics and Walking in Older Adults in a High-Density City: A Study From a Chinese Megacity

2020

The built environment is an important factor affecting physical activity, especially walkability. Walkability is used to characterize the user friendliness of outdoor physical activity. However, studies on walkability and physical activity are mainly concentrated on low-density Western cities. Study on the walkability of high-density cities in Asia, especially with the elderly, is seriously lacking. And walkability is often used as a composite indicator. This study mainly re-examines the relationship between the common indicators of walkability (population density, street connectivity, land-use mix, and retail density), transport-related walking, and leisure-time walking with older adults i…

ChinaAsiaPhysical activityUser friendlinesswalking03 medical and health sciences0302 clinical medicineResidence CharacteristicsEnvironmental healthHumansElderly peopleleisure-time walking030212 general & internal medicineBuilt EnvironmentCitiesolder adultsBuilt environmentAgedOriginal Researchwalkabilitylcsh:Public aspects of medicine030503 health policy & servicesPublic Health Environmental and Occupational Healthlcsh:RA1-1270Middle AgedComposite indicatorhigh-density citytransport-related walkingMegacityGeographyWalkabilityEnvironment DesignPublic Health0305 other medical sciencehuman activitiesStatistical correlationFrontiers in Public Health
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Prevalence of Cognitive Frailty, Do Psychosocial-Related Factors Matter?

2020

Cognitive frailty (CF) is a topic of growing interest with implications for the study of preventive interventions in aging. Nevertheless, little research has been done to assess the influence of psychosocial variables on the risk of CF. Our objectives were to estimate the prevalence of CF in a Spanish sample and to explore the influence of psychosocial variables in this prevalence. Physical frailty and cognitive, functional, psychosocial, and socio-demographic aspects were assessed in a sample of 285 participants over 60 years. Univariate and multivariate logistic regression models were carried out. A prevalence of 21.8% (95% CI 17.4&ndash

Cognitive frailtyGerontologyCogniFraSpprevalencecognitive frailtySample (statistics)Logistic regressionArticlelcsh:RC321-57103 medical and health sciences0302 clinical medicinePrevalenceMedicine030212 general & internal medicinepsychosocial factorslcsh:Neurosciences. Biological psychiatry. Neuropsychiatryolder adultsRelated factorsCognitive frailtybusiness.industryGeneral NeuroscienceUnivariateCognitionPsicologiaOlder adultsPsychosocial factorsPreventive interventionbusinessPsychosocial030217 neurology & neurosurgery
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