Search results for "OPERATION"

showing 10 items of 2969 documents

Assessing statistical significance in multivariable genome wide association analysis

2016

Motivation: Although Genome Wide Association Studies (GWAS) genotype a very large number of single nucleotide polymorphisms (SNPs), the data are often analyzed one SNP at a time. The low predictive power of single SNPs, coupled with the high significance threshold needed to correct for multiple testing, greatly decreases the power of GWAS. Results: We propose a procedure in which all the SNPs are analyzed in a multiple generalized linear model, and we show its use for extremely high-dimensional datasets. Our method yields P-values for assessing significance of single SNPs or groups of SNPs while controlling for all other SNPs and the family wise error rate (FWER). Thus, our method tests whe…

0301 basic medicineStatistics and Probability1303 BiochemistryGenotypeOperations researchLibrary sciencePolymorphism Single NucleotideBiochemistryGerman03 medical and health sciences10007 Department of EconomicsPolitical scienceGenome-Wide Association Analysis1312 Molecular Biology1706 Computer Science ApplicationsCluster AnalysisHumansComputer Simulation2613 Statistics and ProbabilityMolecular BiologyEuropean researchGenetics and Population AnalysisComputational BiologyReproducibility of ResultsOriginal Paperslanguage.human_languageComputer Science Applications330 EconomicsComputational MathematicsPhenotype030104 developmental biologyComputational Theory and MathematicsLinear Modelslanguage2605 Computational MathematicsGenome-Wide Association Study1703 Computational Theory and Mathematics
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The adaptive value of tandem communication in ants:Insights from an agent-based model

2021

AbstractSocial animals often share information about the location of resources, such as a food source or a new nest-site. One well-studied communication strategy in ants is tandem running, whereby a leader guides a recruit to a resource. Tandem running is considered an example of animal teaching because a leader adjusts her behaviour and invests time to help another ant to learn the location of a resource more efficiently. Tandem running also has costs, such as waiting inside the nest for a leader and a reduced walking speed. Whether and when these costs outweigh the benefits of tandem running is not well understood. We developed an agent-based simulation model to investigate the conditions…

0301 basic medicineStatistics and ProbabilityForage (honey bee)Adaptive valueOperations researchComputer scienceForagingGeneral Biochemistry Genetics and Molecular BiologyRunning03 medical and health sciences0302 clinical medicineResource (project management)NestAnimalsLearningAgent-based modelGeneral Immunology and MicrobiologyTandemAntsCommunicationApplied MathematicsGeneral MedicineBeesVariable (computer science)030104 developmental biologyModeling and SimulationSocial animalFemaleGeneral Agricultural and Biological Sciences030217 neurology & neurosurgeryTandem running
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A webGIS-based system for real time shelf life prediction

2016

Technologies to acquire and monitor changes in the product shelf life were described.Four different SL predictive models were considered.A simulated transport using a prototype of Smart Logistic Unit was analysed.Real time shelf life prediction system was implemented in a webGIS platform. Shelf-life (SL) prediction and Least Shelf-life First Out (LSFO) stock strategy are important factors in perishable food supply chain in order to reduce quality and economic losses.In particular, distribution represents one of the main critical phases in logistic chain management and only the introduction of monitoring procedure can allow a reduction in food losses. Literature shows several mathematical mo…

0301 basic medicineTruckEngineeringWeb GISMathematical modelOperations researchbusiness.industrySupply chain030106 microbiologyReal-time computingForestry04 agricultural and veterinary sciencesHorticultureCommunications systemShelf life040401 food scienceAutomationComputer Science Applications03 medical and health sciences0404 agricultural biotechnologyAssisted GPSSettore ING-IND/17 - Impianti Industriali MeccaniciGlobal Positioning SystembusinessAgronomy and Crop Science
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Changes in the international wine market competitiveness

2017

This study offers a contribution to understanding the complexity of the international wine trade analysing the specialisation patterns of 14 among the most important wine world actors in the period 2007–2016, in order to verify if the patterns of comparative advantages for the trade of this countries have experienced significant changes. Using the Lafay index, as a comparative advantage measure, our results reveal deep changes in the global wine market exchange. Our result constitutes a base element for the future development of the competitive scenario and provides some both theoretical and practical implications. In the baseline projection, the maintenance of the competitive position is…

0301 basic medicineWineWine trade.030109 nutrition & dieteticsIndex (economics)Information Systems and ManagementComparative advantageTrade specialisationManagement Science and Operations Research03 medical and health sciencesOrder (exchange)Settore AGR/01 - Economia Ed Estimo RuralePosition (finance)BusinessElement (criminal law)Business and International ManagementBaseline (configuration management)Practical implicationsIndustrial organizationComparative advantageLafay indexInternational Journal of Globalisation and Small Business
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Curve Extraction by Geodesics Fusion: Application to Polymer Reptation Analysis

2016

© Springer International Publishing Switzerland 2016. In the molecular field, researchers analyze dynamics of polymers by microscopy: several measurements such as length and curvature are performed in their studies. To achieve correct analysis they need to extract the curve representing as good as possible the observed polymer shape which is a grayscale thick curve with noise and blur. We propose, in this paper, a method to extract such a curve. A polymer chain moves in a snake-like fashion (Reptation): it can self-intersect and form several complex geometries. To efficiently extract the different geometries, we generate the curve by computing a piecewise centerline browsing the shape by ge…

0301 basic medicine[ INFO ] Computer Science [cs]GeodesicGeometry02 engineering and technologyCurvature03 medical and health sciencesGraph traversalMolecular image analysis[INFO]Computer Science [cs]Grayscale curvesMorphological operationsdistanceMathematicsMicroscopyCurve orientationMathematical analysis021001 nanoscience & nanotechnologyReptation030104 developmental biologyGeodesics fusionPiecewiseShape extractionCurve sketching0210 nano-technologyShape analysis (digital geometry)
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Gynecologic cancers in pregnancy: guidelines based on a third international consensus meeting

2019

We aimed to provide comprehensive protocols and promote effective management of pregnant women with gynecological cancers. New insights and more experience have been gained since the previous guidelines were published in 2014. Members of the International Network on Cancer, Infertility and Pregnancy (INCIP), in collaboration with other international experts, reviewed existing literature on their respective areas of expertise. Summaries were subsequently merged into a manuscript that served as a basis for discussion during the consensus meeting. Treatment of gynecological cancers during pregnancy is attainable if management is achieved by collaboration of a multidisciplinary team of health c…

0301 basic medicinemedicine.medical_specialtyCognitiveGenital Neoplasms FemaleInternational Cooperation[SDV.CAN]Life Sciences [q-bio]/CancerCancer Chemotherapy Cognitive Gynecologic Offspring Pregnancy[SDV.MHEP.GEO]Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetrics03 medical and health sciencesGenital Neoplasms Female/therapyGynecologicOffspring0302 clinical medicineSDG 3 - Good Health and Well-beingPregnancyHealth caremedicinePrenatal Exposure Delayed Effects/etiologyHumansChemotherapyRadiation treatment planningIntensive care medicineSocieties MedicalCancerPregnancy Complications Neoplastic/therapyPregnancyVaginal deliverybusiness.industryCancerHematologymedicine.diseasePrognosis3. Good healthCancer registryLong-term care030104 developmental biologyOncology030220 oncology & carcinogenesisPrenatal Exposure Delayed EffectsPractice Guidelines as TopicFemalePractice Guidelines as Topic/standardsbusinessBreast feedingPregnancy Complications Neoplastic
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European contribution to the study of ROS : A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

2017

WOS: 000410470000009

0301 basic medicinereactive oxygen species ; reactive nitrogen species ; redox signaling ; oxidative stress ; antioxidants ; redox therapeuticsRedox signalingInternational CooperationSMOOTH-MUSCLE-CELLS[SDV]Life Sciences [q-bio]Clinical BiochemistryISCHEMIA-REPERFUSION INJURYReviewddc:616.07Bioinformaticsmedicine.disease_causeBiochemistryAntioxidants0302 clinical medicineENDOPLASMIC-RETICULUM STRESSCost actionlcsh:QH301-705.5ComputingMilieux_MISCELLANEOUSmedia_commonlcsh:R5-920Redox therapeuticsReactive nitrogen species3. Good healthVariety (cybernetics)MANGANESE SUPEROXIDE-DISMUTASECHRONIC GRANULOMATOUS-DISEASERisk analysis (engineering)ddc:540lcsh:Medicine (General)Oxidation-ReductionSignal TransductionSocieties ScientificPULMONARY ARTERIAL-HYPERTENSIONMedicinaEstrès oxidatiuBiology03 medical and health sciencesAntioxidants ; Oxidative Stress ; Reactive Nitrogen Species ; Reactive Oxygen Species ; Redox Signaling ; Redox TherapeuticsJournal Articlemedicinemedia_common.cataloged_instanceAnimalsHumans[CHIM]Chemical SciencesEuropean UnionEuropean unionNITRIC-OXIDE SYNTHASETANDEM MASS-SPECTROMETRYMolecular BiologyMITOCHONDRIAL OXIDATIVE STRESSGROWTH-FACTOR-BETAOrganic ChemistryDisease progressionBiology and Life SciencesOxidation reductionManganese Superoxide Dismutase030104 developmental biologylcsh:Biology (General)Oxidative stressReactive oxygen species030217 neurology & neurosurgeryOxidative stressRedox biology
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Evaluating a hierarchical approach to landscape-level harvest scheduling

2018

Forest planning at the landscape level has the potential to become a large intractable problem. In Finland, Metsähallitus (the state enterprise that manages federally owned land) creates strategic plans to determine the appropriate harvest level. While these plans are feasible, they are not implementable in practice as the harvests are scattered temporally and spatially. Requiring that harvests be organized both temporally and spatially for practical implementation can result in an intractable problem. Through a hierarchical approach, the problem can be organized into steps in which the intractable problem is broken down into smaller easily solvable parts. As an approximation technique, th…

040101 forestryStrategic planningForest planningGlobal and Planetary ChangeIterative and incremental developmentOptimization problem010504 meteorology & atmospheric sciencesEcologyOperations researchComputer scienceForestry04 agricultural and veterinary sciences01 natural sciencesScheduling (computing)Landscape level0401 agriculture forestry and fisheriesState (computer science)Selection (genetic algorithm)0105 earth and related environmental sciencesCanadian Journal of Forest Research
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Groupthink and Project Performance: The Influence of Personal Traits and Interpersonal Ties

2015

Contains fulltext : 166103.pdf (Publisher’s version ) (Closed access) This study explores whether the negative impact of “groupthink concurrence-seeking behavior” (GTB) on business process reengineering (BPR) projects is affected by group members personal traits and interpersonal ties within the group. To this purpose we conduct and present the results of a longitudinal controlled field experiment over 18 BPR projects lasting 3 months and involving 18 teams comprising 71 first-year MBA students. The main contribution of this study is twofold. First, we explicitly consider and measure the core construct of groupthink phenomenon: that is, GTB. Existing organizational behavior literature has, …

05 social sciencesApplied psychologyConscientiousnessBehavioral operations managementInterpersonal communicationBusiness process reengineeringManagement Science and Operations ResearchSettore ING-IND/35 - Ingegneria Economico-GestionaleIndustrial and Manufacturing EngineeringBusiness process reengineeringInterpersonal tiesOrganizational behaviorPhenomenonConcurrence-seeking behaviorManagement of Technology and InnovationBehavioral operations management; Business process reengineering; Concurrence-seeking behavior; Groupthink; Industrial and Manufacturing Engineering; Management Science and Operations Research; Management of Technology and Innovation0502 economics and business050211 marketingPerceived controlMarketingPsychologyConstruct (philosophy)Institute for Management ResearchGroupthink050203 business & management
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The look of writing in reading. Graphetic empathy in making and perceiving graphic traces

2021

This article presents preliminary considerations and results from a research project designed to investigate the relation between (i) gestures, (ii) graphic traces and (iii) perceptions. More specifically, the project aims to test the hypothesis that graphic traces, including handwriting, can set up graphetic empathy between writers and readers of traces across long temporal and spatial distances. Insofar as a graphic trace is lawfully related to the gesture by which it came into being, the trace itself will hold information about the gesture, which may resonate with the sensorimotor system of a perceiver as if they themselves performed the gesture. If this is in fact so, it will have impor…

050101 languages & linguisticsLinguistics and LanguageNeurophenomenologymedia_common.quotation_subjectEmpathyProsody050105 experimental psychologyLanguage and Linguistics[SCCO]Cognitive sciencePhonetic empathyHandwritingPerceptionReading (process)0501 psychology and cognitive sciencesSet (psychology)ComputingMilieux_MISCELLANEOUSmedia_commonCognitive scienceOperationalization05 social sciencesElicitation interviewAffordanceTrace (semiology)PsychologyGraphetic empathyTraceGesture
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