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Analysis of Exosomal Cargo Provides Accurate Clinical, Histologic and Mutational Information in Non-Small Cell Lung Cancer

2022

Simple Summary Non-small cell lung cancer (NSCLC) is the second most commonly diagnosed cancer and the leading cause of cancer-related death worldwide. Clinical decision-making depends on the histological classification; however, tissue biopsy is frequently not technically feasible due to tumor location or limited tissue samples. Therefore, we propose to find clinical, molecular and histological biomarkers using a minimally invasive approach based on the analysis of the cargo of the blood extracellular vesicles. Exosomes are membranous vesicles present in several biological fluids, which carry biological information to distant tissues, regulating several tumor processes. This study aims to …

squamous cell carcinomaCancer ResearchtumorspheresMICRORNASBIOMARKERSCANCER/TESTIS ANTIGENexosomesNSCLCnon-small cell lung cancer; liquid biopsy; exosomes; extracellular vesicles; cell cultures; adenocarcinoma; squamous cell carcinoma; biomarker; tumorspheresMECHANISMSRNASMICROARRAYIMMUNOTHERAPYCàncernon-small cell lung cancerScience & Technologyadenocarcinomaliquid biopsycell culturesSTATISTICSOncologyPulmonsbiomarkerextracellular vesiclesLife Sciences & Biomedicine
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Using uncertain preferential information from stakeholders to assess the acceptability of alternative forest management plans

2017

In forest management planning, participatory planning processes are often encouraged as a means to acquire relevant information and to enhance the stakeholders' acceptability of alternative plans. This requires the aggregation of the stakeholders' preferences that can be done in a wide variety of manners. The aggregation process strives to reduce the information into a single set of preferences that simplifies the information and allows for the use of discrete decision support tools. Depending on how the preferences are aggregated, a wide range of plan rankings can emerge. Although this range of ranking complicates the issue of plan selection, it does highlight the uncertainty involved in a…

stochastic multicriteria acceptability analysisstochastic preferencesComputer scienceStrategy and Managementpäätöksentekostokastinen monikriteerinen arvostusanalyysiForest management0211 other engineering and technologiesGeneral Decision Sciences02 engineering and technologypairwise comparisonsstochastic programminggroup decision makingsidosryhmätryhmätEnvironmental planning040101 forestryStochastic multicriteria acceptability analysis021103 operations researchbusiness.industryEnvironmental resource management04 agricultural and veterinary sciences15. Life on landStochastic programmingGroup decision-makingta11810401 agriculture forestry and fisheriesPairwise comparisonmetsänhoitobusinessosallistava suunnitteluJournal of Multi-Criteria Decision Analysis
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Data for: Biomimetic transformation of polyphosphate microparticles during restoration of damaged teeth

2018

Highlights:•Demineralization of enamel and dentin is caused by chemical processes•Polyphosphate is a natural inorganic polymer which can be fabricated biomimetically into novel amorphous microparticles•Amorphous polyphosphate particles are morphogenetically active in vitro and in vivo•These polyphosphate particles restore damaged enamel and dentin •Dentifrice, supplemented with polyphosphate particles, sustainably solidifies enamel and dentin THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOVE

stomatognathic diseasesNatural Compoundstomatognathic systemInterdisciplinary sciencesOther
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Gastrointestinal Stromal Tumors (GISTs)

2021

Gastrointestinal stromal tumors (GISTs) are a group of tumors that, over the past 15 years, has emerged from a poorly understood neoplasm to a well-defined tumor entity. GISTs are highly resistant to conventional chemotherapy and, in the past, were typically managed surgically.

stomatognathic diseasesPathologymedicine.medical_specialtyStromal cellbusiness.industrymedicineConventional chemotherapyNeoplasmGastrointestinal stromal tumors (GISTs)businessmedicine.diseaseneoplasmsdigestive system diseases
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Valoración clínica del estado dental y periodontal en un grupo de pacientes oncológicos, previo inicio de la quimioterapia

2006

Objetivos: Valorar el estado bucodental en 88 pacientes con cánceres corporales, previo al inicio de su tratamiento quimioterápico. Diseño del estudio: Estudiamos 88 pacientes con cánceres de diferentes localizaciones corporales y los comparamos con un grupo control. Analizamos la placa dental (mediante el índice de Silness y Löe), el estado dental (mediante el índice CAO.D) y el estado periodontal (índice CPI modificado). Resultados: En el grupo de pacientes oncológicos, la media del índice de placa de Silnness y Löe fue de 1,28±0,11. Los pacientes presentaban múltiples ausencias dentarias, siendo la media de dientes ausentes por caries de 7,55±0,80. También se observó que la media de cari…

stomatognathic diseasesstomatognathic systemestado dental y periodontalUNESCO::CIENCIAS MÉDICASChemotherapyQuimioterapiadental and periodontal status:CIENCIAS MÉDICAS [UNESCO]
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Le recherche de l'identité à deux voix : Haroun et Meursault

2017

In his novel entitled The Meursault Investigation (Meursault, contre-enquête) Kamel Daoud shows human weakness and anger against the religion, the same as they are depicted in Albert Camus’s works. His character, Haroun, who is a brother of the Arab killed in The Stranger by Camus, is in the quest for his identity. Being traumatized by his mother’s hold over him, he learns French in order to be able to express his disappointment over the world and his country where he feels as a stranger.

strangerAlbert CamuslanguagereligionmotherculpabilityKamel Daoudidentity
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Students' usage patterns of video recorded lectures in an undergraduate mathematics course

2018

International audience; It is customary for some universities to offer recordings of live lectures to students. Whether this improves learning and academic performance is debated in the literature. As with most technology, correct usage can lead to increased academic performance, but there are also usage patterns that can be considered counter productive, especially for learning mathematics. In order to investigate patterns in students' usage of such online recorded live lectures, we analyze log files from a server holding the recordings of an undergraduate mathematics course. This poster presents results from the statistical analysis and discusses some of the usage patterns found in light …

streaming media.teachers' and students' practices at university level[SHS.EDU]Humanities and Social Sciences/Education[MATH.MATH-HO]Mathematics [math]/History and Overview [math.HO][SHS.EDU] Humanities and Social Sciences/Education[MATH.MATH-HO] Mathematics [math]/History and Overview [math.HO]video recorded lecturesthe role of digital and other resources in university mathematics education
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STUDENTS’ PERSPECTIVES ON THE IMPLEMENTATION OF MUSICAL ACTIVITIES IN PRESCHOOL EDUCATION

2018

Aim. The aim of the study is to find out students’ perspectives on the necessity, readiness and disturbing factors of implementing musical activities in preschool. The theoretical part of the paper describes the particularity of preschool teachers’ work, the children’s interest in musical activities, and the benefits of implementing musical activities in preschool. 
 Method. The empirical study involved 168 students (N=168), of which 132 students (N=132) are already working as preschool teachers in parallel with their study at the university. The study identified three questions: why do preschool teachers use musical activities? What factors prevent a preschool teacher from using music…

students05 social sciencespreschool teacher0211 other engineering and technologies050301 education021107 urban & regional planning02 engineering and technologyMusicalmusical activitieslcsh:Education (General)Likert scaleKey factorsEmpirical researchMathematics educationlcsh:H1-99preschool educationlcsh:Social sciences (General)Psychologylcsh:L7-9910503 educationPreschool educationCompetence (human resources)Journal of Education Culture and Society
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Enabling and constraining family: young women building their educational paths in Tanzania

2015

For an increasing number of African girls and women, upgrading the level of education has become a strategy for life improvement. This paper analyses the role that family plays in enabling women's education and contributes to understanding on the interconnectivity of education, work and family in women's lives in collective societies. The analysis focuses on how young Tanzanian women perceive the role of family and education in their ‘youth task’, of becoming adult. The analysis is based on interviews with seven young Tanzanian women enrolled in non-formal secondary education and nine professional women enrolled in higher education. The results show that the women were determined to pursue …

sub-Saharan AfricaFurther educationfamilySecondary educationSociology and Political ScienceHigher educationeducationDevelopmentFamily relationsta516Sociology10. No inequalityConstraint (mathematics)biologybusiness.industry4. Education05 social sciences050301 educationGeneral Social SciencesGender studieseducational pathsbiology.organism_classificationyouth taskTanzaniaWork (electrical)050903 gender studies5141 Sociology516 Educational sciences0509 other social sciencesbusiness0503 educationCommunity, Work & Family
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il volto della morte: le maschere funerarie della sepoltura dei preti morti di Gangi

2014

riassunto — Le mummie moderne e il signifcato recondito della doppia sepoltura nelle culture mediterranee moderne sono da tempo ampiamente dibattuti. In questo lavoro si discute di una particolare “collezione” di corpi di ecclesiastici, mummifcati ed esposti in un comune montano madonita della Sicilia, Gangi. I corpi, principalmente risalenti al XIX secolo, mummifcati per colatura come nella tradizione del tempo e vestiti degli abiti talari, sono esposti nel piano sottostante della Chiesa Madre, in quella che nella tradizione è detta la “fossa dei parrini” (fossa dei preti). Le mummie, a differenza di altri siti siciliani e mediterranei, sono altresì corredate di sonetto commemorativo e di …

summary — The modern mummies and the inner meaning of the double burial in Mediterranean cultures have long been debated. In this paper we discuss a particular “collection” of ecclesiastical bodies mummifed and displayed in a small mountain town of Sicily Gangi in the Madonie Mountains. The bodies dating back to the nineteenth century mummifed by pouring in the tradition of the time and carefully dressed in robes are exposed in the lower foor of the Chiesa Madre in what the tradition is called “fossa dei parrini” (pit of priests). The mummies unlike other Sicilian and Mediterranean sites are accompanied by commemorative sonnet and death mask made of fnish wax. The primary interest of our study was aimed specifcally at this particular manifestation of the double burial complex which lies in the representation of the face. The work expresses an examination of the concept of death mask in antiquity and leads to the conclusion that the place for its scenic values ritualization should be designed to the ostentation and the consolidation of the image of the Church and of the his power within the small rural society.Settore BIO/08 - Antropologia
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