Search results for "OTU"

Dose-dependent expression of CLIP2 in post-Chernobyl papillary thyroid carcinomas

2015

Summary This study showed a clear dose-response relationship for the CLIP2 radiation marker in post-Chernobyl papillary thyroid carcinoma cohorts for young patients and hints to different molecular mechanisms in tumors induced at low doses compared to moderate/high doses.

Botox® for idiopathic overactive bladder: efficacy, duration and safety. Effectiveness of subsequent injection

2012

Purpose To test the efficacy, duration and safety of 100 U of botulinum toxin type A (BoNT/A) in women affected by idiopathic detrusor overactivity (IDO) and the effectiveness of subsequent injections. Methods In this double centre, prospective study con- ducted from March 2008 to March 2010, we selected women affected by IDO who failed to respond to various antimuscarinic agents, reported intolerable anticholinergic side-effects or contraindication to their use, also without any response to tibial stimulation. Medical history, physi- cal examination, standard urodynamic examination, uri- nalysis, urine culture, a 4-day voiding diary and a quality of life questionnaire were requested for al…

Study on the association between sleep disorders versus oral health related variables

2020

Background To study the association between sleep quality and oral health related variables, which still have conflicts in the literature. Material and Methods This was a population-based case-control study between subjects with versus without sleep disorders from the Brazilian Public Health System (SUS), city of Maringá (N=1,643). Subjects answered self-reported questionnaires: a) Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD), b) Sleep Assessment Questionnaire (SAQ) and c) North York Dental Health Survey (NYDHS). Results No significant difference was found for gender, marital status, or income; however, non-Caucasians, people with lower levels of education, and tho…

Structural validity of the Boston Carpal Tunnel Questionnaire and its short version, the 6-Item CTS symptoms scale : a Rasch analysis one year after …

2020

Abstract Background: The Boston Carpal Tunnel Questionnaire (BCTQ) and its shorter version, the Six-Item Carpal Tunnel Symptoms Scale (CTS-6), are widely used for assessing function and/or symptoms in patients with carpal tunnel syndrome. This study examined the structural validity of the BCTQ and CTS-6 among patients who had undergone surgery for treatment of carpal tunnel syndrome. Methods: The data for this cross-sectional analysis were obtained from 217 adult patients who had undergone carpal tunnel release surgery one year earlier. All patients completed the CTS-6, Symptom Severity Scale (SSS) and Functional Status Scale (FSS) of the BCTQ at 12 months after surgery. The Rasch Measureme…

A further patient with genitopatellar syndrome requiring multidisciplinary management.

2020

Congenital dermatofibrosarcoma protuberans: 30 years of follow-up

2007

Summary Dermatofibrosarcoma protuberans (DFSP) is a rare fibrohistiocytic tumor that commonly appears in adult patients. Few cases of DFSP in childhood have been reported. We describe a case of congenital DFSP that had been incompletely excised in childhood, and again at 28 years of age. The 33-year-old woman presented with a recurrence. When comparing the histologic features of the previous specimens excised in 1970 and 30 years later, the similar typical storiform pattern of fibromatous cells was found. The small number of proliferation-marker-positive cells was not altered over the course of 30 years. In line with a few additional reports, we suggest that congenital dermatofibrosarcoma p…

State of the Art Literature Review on Network Anomaly Detection

2018

As network attacks are evolving along with extreme growth in the amount of data that is present in networks, there is a significant need for faster and more effective anomaly detection methods. Even though current systems perform well when identifying known attacks, previously unknown attacks are still difficult to identify under occurrence. To emphasize, attacks that might have more than one ongoing attack vectors in one network at the same time, or also known as APT (Advanced Persistent Threat) attack, may be hardly notable since it masquerades itself as legitimate traffic. Furthermore, with the help of hiding functionality, this type of attack can even hide in a network for years. Additi…

A Novel Deep Learning Stack for APT Detection

2019

We present a novel Deep Learning (DL) stack for detecting Advanced Persistent threat (APT) attacks. This model is based on a theoretical approach where an APT is observed as a multi-vector multi-stage attack with a continuous strategic campaign. To capture these attacks, the entire network flow and particularly raw data must be used as an input for the detection process. By combining different types of tailored DL-methods, it is possible to capture certain types of anomalies and behaviour. Our method essentially breaks down a bigger problem into smaller tasks, tries to solve these sequentially and finally returns a conclusive result. This concept paper outlines, for example, the problems an…

State of the Art Literature Review on Network Anomaly Detection with Deep Learning

2018

As network attacks are evolving along with extreme growth in the amount of data that is present in networks, there is a significant need for faster and more effective anomaly detection methods. Even though current systems perform well when identifying known attacks, previously unknown attacks are still difficult to identify under occurrence. To emphasize, attacks that might have more than one ongoing attack vectors in one network at the same time, or also known as APT (Advanced Persistent Threat) attack, may be hardly notable since it masquerades itself as legitimate traffic. Furthermore, with the help of hiding functionality, this type of attack can even hide in a network for years. Additi…

Postnatal alterations of the inhibitory synaptic responses recorded from cortical pyramidal neurons in the Lis1/sLis1 mutant mouse

2006

Mutations in the mouse Lis1 gene produce severe alterations in the developing cortex. We have examined some electrophysiological responses of cortical pyramidal neurons during the early postnatal development of Lis/sLis1 mutant mice. In P7 and P30 Lis1/sLis1 neurons we detected a lower frequency and slower decay phase of mIPSCs, and at P30 the mIPSCs amplitude and the action potential duration were reduced. Zolpidem (an agonist of GABAA receptors containing the alpha1 subunit) neither modified the amplitude nor the decay time of mIPSCs at P7 in Lis1/sLis1 neurons, whereas it increased the decay time at P30. The levels of GABAA receptor alpha1 subunit mRNA were reduced in the Lis1/sLis1 brai…