Dose-dependent expression of CLIP2 in post-Chernobyl papillary thyroid carcinomas

6533b854fe1ef96bd12af421

RESEARCH PRODUCT

Dose-dependent expression of CLIP2 in post-Chernobyl papillary thyroid carcinomas

Maria Blettner Illya A. Likhtarev Mykola Tronko Viktor M. Shpak Martin Selmansberger Julia Hess Alina V. Brenner Horst Zitzelsberger Michael Abend Denise Güthlin Jan Christian Kaiser Kristian Unger Peter Jacob

subject

Adult Oncology endocrine system Cancer Research medicine.medical_specialty Pathology Neoplasms Radiation-Induced Adolescent endocrine system diseases Original Manuscript Cohort Studies Iodine Radioisotopes Thyroid carcinoma Young Adult 03 medical and health sciences 0302 clinical medicine Internal medicine Biomarkers Tumor medicine Carcinoma Humans Thyroid Neoplasms Typing Young adult Child Thyroid cancer 030304 developmental biology 0303 health sciences business.industry Carcinoma Thyroid Dose-Response Relationship Radiation General Medicine medicine.disease Carcinoma Papillary humanities 3. Good health Logistic Models medicine.anatomical_structure Chernobyl Nuclear Accident Thyroid Cancer Papillary Child Preschool 030220 oncology & carcinogenesis Cohort business Microtubule-Associated Proteins Cohort study

description

Summary This study showed a clear dose-response relationship for the CLIP2 radiation marker in post-Chernobyl papillary thyroid carcinoma cohorts for young patients and hints to different molecular mechanisms in tumors induced at low doses compared to moderate/high doses.

year	journal	country	edition	language
2015-01-10	Carcinogenesis

https://doi.org/10.1093/carcin/bgv043

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