Search results for "OUTCOME"
showing 10 items of 5148 documents
Crenobalneotherapy (spa therapy) in patients with knee and generalized osteoarthritis: a post-hoc subgroup analysis of a large multicentre randomized…
2014
Abstract Objective To determine whether the addition of spa therapy to home exercises provides any benefit over exercises and the usual treatment alone in the management of generalised osteoarthritis associated with knee osteoarthritis. Methods This study was a post-hoc subgroup analysis of our randomised multicentre trial ( www.clinicaltrial.gov : NCT00348777 ). Participants who met the inclusion criteria of generalized osteoarthritis (Kellgren, American College of Rheumatology, or Dougados criteria) were extracted from the original randomised controlled trial. They had been randomised using Zelen randomisation. The treatment group received 18 days of spa treatment in addition to a home ex…
Primary endpoint results of the OMEGA Study: One-year clinical outcomes after implantation of a novel platinum chromium bare metal stent.
2014
Bare metal stents (BMS) have similar rates of death and myocardial infarction (MI) compared to drug-eluting stents (DES). DES lower repeat revascularization rates compared to BMS, but may have higher rates of late stent thrombosis (ST) potentially due to impaired endothelialization requiring longer dual anti-platelet therapy (DAPT). OMEGA evaluated a novel BMS designed to have improved deliverability and radiopacity, in comparison to currently available platforms.OMEGA was a prospective, multicenter, single-arm study enrolling 328 patients at 37 sites (US and Europe). Patients received the OMEGA stent (bare platinum chromium element stent) for the treatment of de novo native coronary artery…
Initiation and duration of dual antiplatelet therapy after inpatient percutaneous coronary intervention with stent implantation in Germany: An electr…
2017
Abstract Background Studies assessing the routine outpatient dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) in Germany are scarce. The aim of this study was (i) to investigate the initiation and duration of DAPT after inpatient PCI with stent implantation in Germany, and (ii) to identify factors associated with DAPT discontinuation during the recommended treatment period. Methods This retrospective cohort study was based on data from a large German electronic healthcare database of the years 2004 to 2009. The study population comprised four groups of patients with acute coronary syndrome (ACS) or stable angina pectoris undergoing inpatient PCI with either ba…
Social Emotional Competence, Learning Outcomes, Emotional and Behavioral Difficulties of Preschool Children: Parent and Teacher Evaluations
2022
This paper addresses the role of social emotional competence in the emotional and behavioral problems and learning outcomes of preschool children based on their parents’ and teachers’ evaluations. In this study, we compared the perceptions of teachers and parents when evaluating the same child using the multi-informant assessment. First, the associations and differences between both the informant evaluations were investigated. Second, the correlation of the social emotional competence and emotional, and behavioral difficulties among preschool children was analyzed, separately addressing their parents’ and teachers’ evaluations. Third, the role of the preschool children’s social emotional co…
Efficacy of bendamustine and rituximab in splenic marginal zone lymphoma: results from the phase II BRISMA/IELSG36 study.
2018
Splenectomy in addition to immunotherapy with rituximab can provide quick and sometimes durable disease control in patients with splenic marginal zone lymphoma (SMZL). However, systemic chemotherapy is ultimately required in many cases. The BRISMA (Bendamustine-rituximab as first-line treatment of splenic marginal zone lymphoma)/IELSG (International Extranodal Lymphoma Study Group)36 trial is an open-label, single arm phase II study designed by the IELSG in cooperation with the Fondazione Italiana Linfomi and the lymphoma Study Association according to Simon's two-stage method. The primary endpoint was complete response rate. Fifty-six patients with SMZL diagnosis confirmed on central revis…
Vitrectomía enzimática por inyección intravítrea de plasmina autóloga como tratamiento inicial del edema macular diabético difuso
2008
espanolObjetivo: Determinar si la inyeccion intravitrea de plasmina es efectiva en el tratamiento del edema macular diabetico difuso (EMDD). Diseno: Estudio piloto prospectivo, comparativo, de intervencion, serie de casos. Pacientes: Dieciocho pacientes con edema macular diabetico bilateral, recibieron como primera actuacion terapeutica una inyeccion intravitrea de plasmina en un ojo, sirviendo el ojo contralateral como control. Tratamiento: Inyeccion intravitrea de 0,2 ml de plasmina autologa bajo anestesia topica. La plasmina fue obtenida por un metodo simplificado. Principales medidas: Engrosamiento macular central (EMC) medido por tomografia de coherencia optica (OCT) y agudeza visual (…
BiZact tonsilektomijas un konvencionālās tonsilektomijas metožu salīdzinājums
2022
Paskaidrojošā informācija: Tonsilektomija ir viena no visbiežāk veiktajām ķirurģiskajām operācijām cilvēces vēsturē. Tonsilektomija tehnoloģijas un procedūras gadu gaitā ir attīstījušās, lai uzlabotu pacientu aprūpi saistībā ar intraoperācijas un pēcoperācijas riskiem. Mērķis: Šī pētījuma mērķis ir salīdzināt BiZact tonsilektomijas metodi ar tradicionālo «aukstās pieejas» tērauda tonsilektomijas metodi attiecībā uz ķirurģiskajiem rezultātiem. Nolūks: Klasiskā «aukstās pieejas» tērauda tonsilektomijas metode ir viena no visbiežāk izmantotajām metodēm, un tā ir balstīta uz tonsilektomijas instrumentiem, jo ar tiem ir viegli strādāt, tiem nav nepieciešama elektrība (un līdz ar to tie ir vienkā…
Binge Drinking: The Top 100 Cited Papers
2021
We conducted a review to analyze the 100 most-cited studies on binge drinking (BD) in the Web of Science (WoS) database to determine their current status and the aspects that require further attention. We carried out a retrospective bibliometric analysis in January 2021. The year of publication, authors, design, subject, journal, institution and lead author’s country, as well as the definition of BD, were extracted from the articles. The data on the country, year, thematic category of the journals and their rank were obtained from the Institute for Scientific Information (ISI) Journal Citation Reports 2020. The number of citations was collected from the WoS, and the h index was collected fr…
Diagnostic Performance of 68Ga-PSMA-11 Positron-emission-tomography/Computed-tomography in a Large Cohort of Patients with Biochemical Recurrence of …
2020
Gallium-68 (Ga) prostate-specific-membrane-antigen positron-emission-tomography/computed-tomography is a highly promising method for imaging primary and recurrent prostate cancer. These dual-modality imaging technologies enable whole-body functional and anatomical evaluation in a single session. This study investigated the performance of Ga-prostate-specific-membrane-antigen-11 positron-emission-tomography/computed-tomography for detecting prostate carcinoma in patients with rising prostate-specific-antigen after primary therapy. Six hundred sixty (660) patients with biochemical recurrence referred for positron-emission-tomography/computed-tomography with Ga-prostate-specific-membrane-antig…
Long-term follow-up results of vesico-ureteral reflux treated with subureteral collagen injection (SCIN).
2000
Endoscopic sub-ureteral injection is at the present a widely used technique for the treatment of vesico-ureteral reflux and it has a good range of efficacy, from 50% up to 90% in relation to different grades. In this paper we report our 1-7 year follow-up results of sub-ureteral collagen injection (SCIN).Between 1991 and 1997 we treated with SCIN 129 refluxing ureters in 93 children (60 females and 32 males), mean age 2.1 years (range 3 months-5 years). Fifty-five children had monolateral, but 37 had bilateral reflux. Distribution among different grades was 42 ureters (32.5%) grade 2, 63 (48.8%) grade 3, 24 (18.6%) grade 4. Children were treated with injection of highly purified bovine coll…