Search results for "OUTCOMES"

The impact of deep vein thrombosis in critically ill patients: a meta-analysis of major clinical outcomes

2015

Background. Critically ill patients appear to be at high risk of developing deep vein thrombosis (DVT) and pulmonary embolism during their stay in the intensive care unit (ICU). However, little is known about the clinical course of venous thromboembolism in the ICU setting. We therefore evaluated, through a systematic review of the literature, the available data on the impact of a diagnosis of DVT on hospital and ICU stay, duration of mechanical ventilation and mortality in critically ill patients. We also tried to determine whether currently adopted prophylactic measures need to be revised and improved in the ICU setting. Materials and methods. MEDLINE and EMBASE databases were searched up…

The Valencia Eustress-Distress Appraisal Scale (VEDAS): Validation of the Italian Version

2018

© 2018 by the authors. The aim of this study is to validate the Italian version of the Valencia Eustress-Distress Appraisal Scale (VEDAS). Two hundred and thirty-two Italian workers were involved in the study. Dimensionality, reliability, and concurrent validity were analyzed. Confirmatory factor analysis supported a four-dimensional structure. In addition, the Italian version of the scale showed good internal consistency and validity. The results indicate that the Italian version of the VEDAS is a valid instrument for measuring eustress and distress appraisal in the Italian context. ispartof: SUSTAINABILITY vol:10 issue:11 status: published

Xenon treatment improves short-term and long-term outcomes in a rodent model of traumatic brain injury

2018

Psychometric properties of the Finnish version of the Young Person's Clinical Outcomes in Routine Evaluation (YP-CORE) questionnaire.

2017

An increasing need exists for suitable measures to evaluate treatment outcome in adolescents. YP-CORE is a pan-theoretical brief questionnaire developed for this purpose, but it lacks studies in different cultures or languages.To explore the acceptability, factor structure, reliability, validity, and sensitivity to change of the Finnish translation of YP-CORE.The study was conducted at the Department of Adolescent Psychiatry, Helsinki University Central Hospital. A Finnish translation was prepared by a team of professionals and adolescents. A clinical sample of 104 patients was asked to complete the form together with BDI-21 and BAI, and 92 of them filled the forms again after a 3-month tre…

Leveraging Collaborative Governance: How Co-production Contributes to Outcomes and Public Value in a Small Town

2020

Collaborative governance is increasingly considered an effective approach to improve outcomes and public value. This chapter focuses on co-production as an instrument to implement collaborative governance at local level. It is not uncommon that small towns develop co-production processes to deliver cultural and touristic services. Out of a literature review, the study develops a Dynamic Multidimensional Performance Management framework to explore the impact of co-production on community outcomes. To this end, this chapter discusses the case “Museo Civico di Castelbuono (MCC)”,which concerns the co-production process of the guided tour of the museum’s venue. The resulting model provides insi…

Prospettive di riforma della tutela penale dell'ambiente nel diritto europeo e sovranazionale

2021

Il saggio descrive le prospettive di riforma della normativa penale ambientale, di recente delineatesi tanto a livello internazionale, quanto in ambito europeo. Pur non spingendosi sino a prevedere i possibili esiti delle dinamiche in corso, il contributo non rinuncia ad analizzarne luci ed ombre, anche alla luce delle difficoltà di tipizzazione delle fattispecie incriminatrici determinata dalla particolare complessità della materia ambientale.

Profiling the risk of hepatocellular carcinoma after long-term HCV eradication in patients with liver cirrhosis in the PITER cohort

2023

Background and aims: Severe liver disease markers assessed before HCV eradication are acknowledged to usually improve after the SVR. We prospectively evaluated, in the PITER cohort, the long-term HCC risk profile based on predictors monitored after HCV eradication by direct-acting antivirals in patients with cirrhosis. Methods: HCC occurrence was evaluated by Kaplan-Meier analysis. Cox regression analysis identified the post-treatment variables associated with de-novo HCC; their predictive power was presented in a nomogram. Results: After the end of therapy (median follow-up:28.47 months), among 2064 SVR patients, 119 (5.8%) developed de-novo HCC. The HCC incidence was 1.90%, 4.21%, 6.47% a…

Declines in Sexual Activity and Function Predict Incident Health Problems in Older Adults: Prospective Findings from the English Longitudinal Study o…

2020

The objective of this study was to investigate cross-sectional and longitudinal associations between declines in sexual activity and function and health outcomes in a large population-based sample of older adults. Data were from 2577 men and 3195 women aged ≥ 50 years participating in the English Longitudinal Study of Ageing. Past-year changes in sexual desire, frequency of sexual activity, and ability to have an erection (men)/become sexually aroused (women) were assessed at baseline by self-completion questionnaire. Health outcomes (self-rated health, limiting long-standing illness, doctor-diagnosed diseases of the vascular system, and cancer) were self-reported at baseline (2012/2013) an…

Study design of Heart failure Events reduction with Remote Monitoring and eHealth Support (HERMeS)

2020

Aims: The role of non‐invasive telemedicine (TM) combining telemonitoring and teleintervention by videoconference (VC) in patients recently admitted due to heart failure (HF) (‘vulnerable phase’ HF patients) is not well established. The aim of the Heart failure Events reduction with Remote Monitoring and eHealth Support (HERMeS) trial is to assess the impact on clinical outcomes of implementing a TM service based on mobile health (mHealth), which includes remote daily monitoring of biometric data and symptom reporting (telemonitoring) combined with VC structured, nurse‐based follow‐up (teleintervention). The results will be compared with those of the comprehensive HF usual care (UC) strateg…

Taking into Account Patient Preferences: A Consensus Study on the Assessment of Psychological Dimensions Within Patient Preference Studies

2021

Selena Russo,1,2,* Dario Monzani,3,4,* Cathy Anne Pinto,5 Laura Vergani,3,4 Giulia Marton,3,4 Marie Falahee,6 Gwenda Simons,6 Chiara Whichello,7 Ulrik Kihlbom,8,* Gabriella Pravettoni3,4,* 1Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; 2Discipline of Paediatrics, School of Women’s and Children’s Health, The University of New South Wales, Kensington, NSW, Australia; 3Applied Research Division for Cognitive and Psychological Science, IEO, European Institute of Oncology IRCCS, Milan, Italy; 4Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy; 5Department of Pharmacoepidemiology, Merck & Co., Inc., Kenilwor…