Search results for "OXIDATION"

showing 10 items of 1913 documents

Combination of advanced oxidation processes and active carbons adsorption for the treatment of simulated saline wastewater

2016

Abstract In the present work, an integrated process combining three different technologies, i.e. heterogeneous photocatalysis, homogeneous ozonation and adsorption on granular activated carbon (GAC) was used for the treatment of a synthetic solution simulating saline wastewater. The synergistic effects between the different methods enhance the oxidation rate of the organic compounds in the integrated process, so that its use may result sustainable. It has been found that a relatively low oxidation rate is sufficient to obtain the highest synergy between the three technologies and to maximize the performances. In particular, coupling ozonation and photocatalysis resulted in 20% enhancement i…

ImaginationChemical substancemedia_common.quotation_subjectFiltration and Separation02 engineering and technology010501 environmental sciences01 natural sciencesAnalytical Chemistrylaw.inventionAdvanced oxidation processes Active carbon adsorption Ozonation Photocatalysis Saline wastewaterReaction rateAdsorptionMagazinelawSettore CHIM/01 - Chimica Analitica0105 earth and related environmental sciencesmedia_commonSettore ING-IND/24 - Principi Di Ingegneria ChimicaChemistryEnvironmental engineering021001 nanoscience & nanotechnologyWastewaterChemical engineeringPhotocatalysisSettore CHIM/07 - Fondamenti Chimici Delle Tecnologie0210 nano-technologyScience technology and societySeparation and Purification Technology
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Disulfide stress and its targets in acute pancreatitis

2014

Under physiological conditions, the balance between ROS production and removal properly maintains the intracellular redox-sensitive signaling as well as the appropriate status of protein thiols and disulfides. However, inflammation among other factors can modify this balance causing a rapid increase in intracellular ROS levels and hence thiol oxidation, eventually leading to oxidative stress. In the case of acute pancreatitis, both redox signaling and oxidative stress seem to contribute to the progression of the severe form of the disease. In this review we will focus on the reversible oxidation of protein cysteines during the course of acute pancreatitis. We describe disulfide stress in an…

ImmunologyInflammationmedicine.disease_causechemistry.chemical_compoundmedicineAnimalsHumansImmunology and AllergyCysteineDisulfidesMolecular Targeted TherapyCysteine metabolismPharmacologychemistry.chemical_classificationReactive oxygen speciesGeneral MedicineGlutathionemedicine.diseaseOxidative StressPancreatitischemistryBiochemistryAcute DiseaseAcute pancreatitismedicine.symptomSignal transductionOxidation-ReductionIntracellularOxidative stressSignal Transduction
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A new cell for the study of in situ chemical reactions using X-ray absorption spectroscopy

2005

An in situ cell for reductive and oxidative treatments at different temperatures that allows the possibility of recording data as a function of temperature has been designed and constructed for X-ray absorption experiments at the GILDA beamline BM08 of ESRF. The cell is linked to a mass quadrupole spectrometer providing control of the reaction gases and monitoring of the products. The apparatus allows measurements to be performed both in transmission and fluorescence geometry. The cell was tested by studying the CO oxidation reaction promoted by a Pt/ceria-zirconia-supported catalyst. The CO(2) yield is correlated with the structural results confirming the existence of a strong metal-suppor…

In situNuclear and High Energy PhysicsAnalytical chemistryChemical reactionRedoxCatalysisSpecimen HandlingCatalysisthree-way catalystX-Ray DiffractionAbsorption (electromagnetic radiation)InstrumentationPlatinumX-ray absorption spectroscopyRadiationSpectrometerChemistryTemperatureSpectrometry X-Ray EmissionCarbon Dioxidein situ EXAFSOxygenYield (chemistry)Flow Injection AnalysisZirconiumOxidation-Reductionstrong metal support interaction
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Kinetics of the lipoperoxyl radical-scavenging activity of indicaxanthin in solution and unilamellar liposomes

2007

Abstract The reaction of the phytochemical indicaxanthin with lipoperoxyl radicals generated in methyl linoleate methanol solution by 2,20-azobis(2,4-dimethylvaleronitrile), and in aqueous soybean phosphatidylcholine unilamellar liposomes by 2,20-azobis(2- amidinopropane)hydrochloride, was studied. The molecule acts as a chain-terminating lipoperoxyl radical scavenger in solution, with a calculated inhibition constant of 3.63 £ 105M21 s21, and a stoichiometric factor approaching 2. Indicaxanthin incorporated in liposomes prevented lipid oxidation, inducing clear-cut lag periods and decrease of the propagation rate. Both effects were concentration-dependent, but not linearly related to the p…

Indicaxanthin membranes radical scavenger liposomesLipid PeroxidesAntioxidant12-DipalmitoylphosphatidylcholinePyridinesmedicine.medical_treatmentRadicalLipid Bilayersalpha-TocopherolAmidinesContext (language use)In Vitro TechniquesBiochemistryAntioxidantsLipid peroxidationchemistry.chemical_compoundLipid oxidationSuspensionsPhosphatidylcholineNitrilesmedicineOrganic chemistryLiposomeDose-Response Relationship DrugMolecular StructureMethanolDrug SynergismGeneral MedicineFree Radical ScavengersBetaxanthinsSolutionsKineticschemistryLinoleic AcidsLiposomesPhosphatidylcholinesSolventsLipid PeroxidationIndicaxanthinAzo CompoundsOxidation-ReductionNuclear chemistry
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Redox intermediates of plant and mammalian peroxidases: a comparative transient-kinetic study of their reactivity toward indole derivatives.

2002

Abstract A comparative study on the reactivity of five indole derivatives (tryptamine, N-acetyltryptamine, tryptophan, melatonin, and serotonin), with the redox intermediates compound I (k2) and compound II (k3) of the plant enzyme horseradish peroxidase (HRP) and the two mammalian enzymes lactoperoxidase (LPO) and myeloperoxidase (MPO), was performed using the sequential-mixing stopped-flow technique. The calculated bimolecular rate constants (k2, k3) revealed substantial differences regarding the oxidizability of the substrates by redox intermediates at pH 7.0 and 25°C. With HRP it was shown that k2 and k3 are mainly determined by the reduction potential (E°′) of the substrate with k2 bei…

Indole testTryptamineMammalsIndolesbiologyStereochemistryLactoperoxidaseBiophysicsTryptophanSubstrate (chemistry)PlantsBiochemistryHorseradish peroxidaseRedoxchemistry.chemical_compoundKineticschemistryPeroxidasesbiology.proteinAnimalsLactoperoxidaseMolecular BiologyOxidation-ReductionHorseradish PeroxidasePeroxidaseArchives of biochemistry and biophysics
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THIOPYRANO[2,3-E]INDOL-2-ONES: ANGELICIN HETEROANALOGUES WITH POTENT PHOTOANTIPROLIFERATIVE ACTIVITY

2008

A new class of compounds, the thiopyrano[2,3-e]indol-2-ones, bioisosters of the angular furocoumarin angelicin, was synthesized with the aim of obtaining new photochemotherapeutic agents. In particular 7,8-dimethyl-thiopyranoindolone 6c s showed a remarkable phototoxicity and a great dose UVA dependence reaching IC(50) values at submicromolar level. This latter photoinduced a massive apoptosis and a remarkable photodamage to lipids and proteins. Although it did not intercalate DNA, it was able to cause photooxidation of DNA bases.

IndolesStereochemistryDNA damageUltraviolet RaysAngelicinThiopyrano[23-e ]indol-2-oneClinical BiochemistryPharmaceutical ScienceHL-60 CellsApoptosisThiopyrano[2Antiproliferative activityBiochemistryChemical synthesischemistry.chemical_compoundInhibitory Concentration 50Jurkat CellsAngelicinPhotochemotherapeutic agentsFurocoumarinsDrug DiscoveryThiolactoneTumor Cells CulturedHumansPhotosensitizer3-e ]indol-2-onesMolecular BiologyPhotosensitizing AgentsFurocoumarinOrganic ChemistryProteinsBiological activityThiopyrano[2; 3-e ]indol-2-ones; Angelicin; Antiproliferative activity; Photochemotherapeutic agents; ApoptosisDNASettore CHIM/08 - Chimica FarmaceuticaMitochondriachemistryPhotochemotherapeutic agentMolecular MedicineLipid PeroxidationPhototoxicityDNA Damage
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Association of redox and inflammation-related biomarkers with prognosis in IgA nephropathy: A prospective observational study.

2022

IgA nephropathy (IGAN) has a variable prognosis. Risk stratification tools are usually based on clinical parameters combined with histologic Oxford-MEST-C score. Circulating redox- and inflammation-related biomarkers may be related to histological changes in IGAN. Therefore, we studied the performance of these biomarkers in predicting the rate of GFR-loss in IGAN.This was an observational prospective study. Fifty-seven stable patients with IGAN were examined at baseline and after a mean observational time of 5.9 ± 1.1 years. The main outcome measure was eGFR-loss per year with predefined groups, stable (1.5 ml/min/1,73 mFifteen patients were in the progressive, 11 in the intermediate, and 3…

InflammationGlomerulonephritis IGABiochemistryAdvanced Oxidation Protein ProductsReceptors Tumor Necrosis Factor Type IPhysiology (medical)Disease ProgressionHumansVDP::Medisinske Fag: 700OsteopontinCysteineProspective StudiesOxidation-ReductionBiomarkersGlomerular Filtration RateFree radical biologymedicine
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Cross-talk between oxidative stress and pro-inflammatory cytokines in acute pancreatitis: a key role for protein phosphatases.

2009

Acute pancreatitis is an acute inflammatory process localized in the pancreatic gland that frequently involves peripancreatic tissues. It is still under investigation why an episode of acute pancreatitis remains mild affecting only the pancreas or progresses to a severe form leading to multiple organ failure and death. Proinflammatory cytokines and oxidative stress play a pivotal role in the early pathophysiological events of the disease. Cytokines such as interleukin 1beta and tumor necrosis factor alpha initiate and propagate almost all consequences of the systemic inflammatory response syndrome. On the other hand, depletion of pancreatic glutathione is an early hallmark of acute pancreat…

Inflammationmedicine.disease_causeProinflammatory cytokineDrug DiscoveryPhosphoprotein PhosphatasesMedicineAnimalsHumansPharmacologyInflammationbiologybusiness.industrymedicine.diseaseSystemic inflammatory response syndromeOxidative StressPancreatitisMitogen-activated protein kinaseImmunologyAcute Diseasebiology.proteinAcute pancreatitisPancreatitisCytokinesTumor necrosis factor alphamedicine.symptomMitogen-Activated Protein KinasesbusinessOxidation-ReductionOxidative stressSignal TransductionCurrent pharmaceutical design
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Ozonated Water, Ozonated Water, Ozonated Oil and its Products

2018

Most of us are aware that ozone is basically a treatment of pure oxygen and its effect on the human body is even better. As our human body is made up of 70% of water, we used ozone in many different way, one of them is what we know as ozonated water. As ozone when mix in water it diluted thoroughly and highly purifies the water, as it is soluble in water. It maintain its tri-oxygen identity. Biological Properties of Ozonated Water: •                    It kills viruses, bacteria, fungi and algae on contact. •                    It breakdown harmful synthetic chemicals into less dangerous molecules. •                    It purifies the blood by rupturing the cell wall of the microorganisms. …

IngredientLipid oxidationChemistryDisinfectantBiological propertymedicineFood sciencePeroxide valueIrritationDandruffmedicine.symptommedicine.disease_causeOzone therapyJournal of Ozone Therapy
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The Pd3(dppm)3(CO)n clusters (n = 1-,2-); rare cases of anionic palladium species.

2010

Two novel anionic palladium clusters, Pd(3)(dppm)(3)(CO)(n-) (Pd(3)(n); n = 1-,2-) were electrochemically generated from the dicationic cluster Pd(3)(2+) in 0.2 M THF/Bu(4)NPF(6)via two first consecutive reversible 1-electron reductions (Pd(3)(2+) + 1 e(-) ⇌ Pd(3)(+), -0.210, and Pd(3)(+) + 1 e(-) ⇌ Pd(3)(0), -0.470 V vs. SCE) followed by two others at -2.350 (Pd(3)(0) + 1 e(-) ⇌ Pd(3)(1-), reversible) and at -2.690 V vs. SCE (Pd(3)(1-) + 1 e(-) ⇌ Pd(3)(2-), irreversible). The chemical stability and instability, respectively, of the Pd(3)(dppm)(3)(CO)(n-) clusters (Pd(3)(n); n = 1-,2-) at the time scale of the electrochemical experiments were addressed by DFT computations. Indeed, geometry …

Inorganic ChemistryBond lengthStereochemistryOxidation stateChemistryCluster (physics)Substrate (chemistry)chemistry.chemical_elementChemical stabilityElectrochemistryMedicinal chemistryRelative stabilityPalladiumDalton transactions (Cambridge, England : 2003)
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