Search results for "Obstetric labor"

showing 10 items of 23 documents

Is the beta3-adrenoceptor (ADRB3) a potential target for uterorelaxant drugs?

2007

International audience; The management of premature birth still remains unsatisfactory. Since the relative lack of efficiency and/or safety of current tocolytic agents have been highlighted, it is necessary to develop new uterorelaxant drugs deprived of important maternal and foetal side effects. Our work reported in this review focuses on a potential new target for tocolytic drugs, the beta3-adrenoceptor (ADRB3). This third type of ADRB is shown to be present and functional in human myometrium. We demonstrated that ADRB3 agonists are able to inhibit in-vitro spontaneous contractions of myometrial strips, via a cyclic AMP-mediated pathway. Furthermore, we established that ADRB3 is the predo…

Muscle RelaxationMESH : Receptors Adrenergic beta-3MESH : Adrenergic beta-AgonistsUterusAdrenergic beta-3 Receptor AgonistsMESH: Adrenergic beta-AgonistsPharmacologyUterine contractionUterine Contraction0302 clinical medicineMESH: PregnancyMESH : UterusPregnancyObstetrics and GynaecologyMedicineMESH : FemaleMESH: Obstetric Labor Premature[ SDV.MHEP.GEO ] Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetricsreproductive and urinary physiology0303 health sciencesMESH : MyometriumMyometriumMESH : Obstetric Labor PrematureObstetrics and GynecologyAdrenergic beta-Agonists3. Good healthmedicine.anatomical_structureMuscle relaxation030220 oncology & carcinogenesisTocolyticMESH: Uterine ContractionMyometriumMESH: MyometriumMESH: UterusFemalemedicine.symptomTocolytic agentmedicine.medical_specialtyAdrenergic receptorAdrenergic beta-3 Receptor Agonists[SDV.MHEP.GEO]Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetricsMESH : Muscle Relaxation03 medical and health sciencesObstetric Labor PrematureInternal medicineHumans030304 developmental biologyMESH: Humansbusiness.industryMESH : HumansUterus[SDV.MHEP.GEO] Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetricsMESH : PregnancyEndocrinologyProceedingsReceptors Adrenergic beta-3MESH: Muscle RelaxationbusinessMESH: Receptors Adrenergic beta-3MESH: FemaleMESH : Uterine Contraction
researchProduct

Periodontitis and preterm delivery. A review of the literature

2005

The aim of this paper was to review the relationship between periodontitis and preterm delivery (PTD). Original papers on this subject, published in English until the first quarter of 2004, were located in the MEDLINE/PubMed database. Additional papers were obtained by searching reference lists of previously published review papers. Case control studies pointed to an association between periodontitis and increased rates of PTD of low birth-weight (LBW) infants. Longitudinal studies showed that the incidence or progression of periodontitis during pregnancy may be an independent risk factor for PTD and LBW. Microbiological, immunological and animal model studies suggested that periodontal pat…

Obstetric Labor PrematurePregnancyChronic DiseaseAnimalsHumansFemalePeriodontitis
researchProduct

Exposure to trihalomethanes through different water uses and birth weight, small for gestational age, and preterm delivery in Spain

2011

Background: Evidence associating exposure to water disinfection by-products with reduced birth weight and altered duration of gestation remains inconclusive. Objective: We assessed exposure to trihalomethanes (THMs) during pregnancy through different water uses and evaluated the association with birth weight, small for gestational age (SGA), low birth weight (LBW), and preterm delivery. Methods: Mother–child cohorts set up in five Spanish areas during the years 2000–2008 contributed data on water ingestion, showering, bathing, and swimming in pools. We ascertained residential THM levels during pregnancy periods through ad hoc sampling campaigns (828 measurements) and regulatory data (264 me…

PediatricsFetus -- CreixementBathingHealth Toxicology and MutagenesisEspaña:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Cohort Studies:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models Theoretical [Medical Subject Headings]small for gestational agePregnancynewbornFemeninosExposición a Riesgos Ambientales:Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy [Medical Subject Headings]:Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings]water pollutionInfeccions respiratòries -- EpidemiologiaAdultodisinfection by-products:Named Groups::Persons::Age Groups::Infant::Infant Newborn::Infant Low Birth Weight [Medical Subject Headings]Modelos TeóricosEnvironmental exposurepremature birthNacimiento PrematuroHumanos:Health Care::Environment and Public Health::Public Health::Environmental Pollution::Environmental Exposure [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Logistic Models [Medical Subject Headings]Premature birthInfant Small for Gestational AgeGestation:Named Groups::Persons::Age Groups::Infant::Infant Newborn::Infant Low Birth Weight::Infant Small for Gestational Age [Medical Subject Headings]Femaleepidemiologymedicine.symptomAigua -- DepuracióAdultmedicine.medical_specialtytrihalomethanesContaminantes Químicos del AguaEmbarazoBirth weight:Named Groups::Persons::Age Groups::Infant::Infant Newborn [Medical Subject Headings]Embaràs -- Aspectes nutricionalsRecién nacidoRecién Nacido Pequeño para la Edad GestacionalEnvironmental healthmedicine:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]cohort studyModelos LogísticosHumanslow birth weightEpidemiologiaRecién Nacido de Bajo Peso:Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons Halogenated::Trihalomethanes [Medical Subject Headings]Pregnancybusiness.industryTrihalometanoResearchPublic Health Environmental and Occupational HealthInfant Newbornbirth weightEnvironmental ExposureInfant Low Birth WeightModels Theoreticalmedicine.diseaseLow birth weightLogistic Models:Check Tags::Female [Medical Subject Headings]Spain:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies [Medical Subject Headings]Small for gestational age:Chemicals and Drugs::Chemical Actions and Uses::Toxic Actions::Environmental Pollutants::Water Pollutants::Water Pollutants Chemical [Medical Subject Headings]:Diseases::Female Urogenital Diseases and Pregnancy Complications::Pregnancy Complications::Obstetric Labor Complications::Obstetric Labor Premature::Premature Birth [Medical Subject Headings]businessEstudios de CohortesWater Pollutants Chemical
researchProduct

AISF position paper on liver transplantation and pregnancy: Women in Hepatology Group, Italian Association for the Study of the Liver (AISF)

2016

After the first successful pregnancy in a liver transplant recipient in 1978, much evidence has accumulated on the course, outcomes and management strategies of pregnancy following liver transplantation. Generally, liver transplantation restores sexual function and fertility as early as a few months after transplant. Considering that one third of all liver transplant recipients are women, that approximately one-third of them are of reproductive age (18-49 years), and that 15% of female liver transplant recipients are paediatric patients who have a >70% probability of reaching reproductive age, the issue of pregnancy after liver transplantation is rather relevant, and obstetricians, paedi…

Risk AssessmentFertility; Immunosuppression; Liver transplantation; PregnancyImmunosuppressive AgentPregnancyMedicalFertility; Immunosuppression; Liver transplantation; Pregnancy; Hepatology; GastroenterologyHumansFertility; Immunosuppression; Liver transplantation; Pregnancy; Gastroenterology; HepatologyObstetric Labor ComplicationSocieties MedicalLiver transplantationHepatologyPostpartum PeriodPregnancy OutcomeGastroenterologyFertility; Immunosuppression; Liver transplantation; Pregnancy; Contraception; Female; Fertility; Gastroenterology; Humans; Italy; Obstetric Labor Complications; Postpartum Period; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications; Risk Assessment; Societies Medical; Immunosuppressive Agents; Liver Transplantation; Pregnancy OutcomeFertility; Immunosuppression; Liver transplantation; Pregnancy; Contraception; Female; Fertility; Gastroenterology; Humans; Italy; Obstetric Labor Complications; Postpartum Period; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications; Risk Assessment; Societies Medical; Immunosuppressive Agents; Liver Transplantation; Pregnancy Outcome; Hepatology; GastroenterologyPregnancy ComplicationObstetric Labor ComplicationsPregnancy ComplicationsContraceptionFertilitysurgical procedures operativeItalyPractice Guidelines as TopicFemaleSocietiesImmunosuppressive AgentsImmunosuppressionHuman
researchProduct

Occiput-spine relationship: shoulders are more important than head.

2017

BACKGROUND:To understand the role of fetal spine position in determining a fetal head position at the time of birth and modality of delivery. PATIENTS AND METHODS: This was a multicenter prospective observational study. Fetal occiput and spine position were evaluated by intrapartum ultrasound. Eighty-six women were eligible for inclusion in the study. Occiput rotational movements and modality of delivery in relation to the fetal spine position were investigated. RESULTS: At the beginning of labor, fetal occiput was in a posterior position in 52.3% of cases and, in 81.5% of cases the spine was in an anterior transverse position. At birth, occiput and spine were both in an anterior position i…

Shoulders head occipit-spine relationshipShoulderOcciput-Spine RelationshipSocio-culturaleFetal spineObstetric labor Fetal spine Intrapartum ultra- sound Occiput posterior Occiput-Spine Relationship.SpineUltrasonography PrenatalLabor PresentationObstetric labor Fetal spine Intrapartum ultrasound Occiput posterior Occiput-Spine Relationship.Obstetric laborFetusPregnancyOcciput posteriorHumansFemaleProspective StudiesHeadIntrapartum ultra- soundEuropean review for medical and pharmacological sciences
researchProduct

Anti-fetal immune response mechanisms may be involved in the pathogenesis of placental abruption

2003

Placental abruption is an unpredictable severe complication in pregnancy. In order to investigate the possibility that the activation of the fetal nonadaptive immune system may be involved in the pathogenesis of this disease, IL-6 release from cord blood monocytes was examined by intracellular cytokine staining and flow cytometric analysis. Our results demonstrate that preterm placental abruption (n = 15) in contrast to uncontrollable preterm labor (n = 33) is associated with significantly (P < 0.001) increased release of IL-6 from the fetal monocytes. The same holds true for rhesus disease (n = 9, P < 0.001) that is characterized by a maternal production of antibodies against the rhesus-D …

Time FactorsImmunologyAntibodiesMonocytesPreeclampsiaPathogenesisFetusObstetric Labor PrematureImmune systemHLA AntigensPregnancyHumansImmunology and AllergyMedicineAbruptio PlacentaeFetusPregnancybiologyPlacental abruptionbusiness.industryImmunityFetal Bloodmedicine.diseaseFetal circulationImmunologybiology.proteinFemaleAntibodybusinessClinical Immunology
researchProduct

Multimodality 3-dimensional volumetric ultrasound in obstetrics and gynecology with an emphasis in HDlive technique.

2013

HDlive (high-definition live or real-time US), a new ultrasound software, combines a movable virtual adjustable light source in a software that calculates the proportion of light reflecting through surface structures, depending on light direction. The light source can be manually positioned to illuminate the desired area of interest. The ultrasound technician can control light intensity to create shadows that enhance image quality. HDlive is an innovation that will render even more realistic images of fetal anatomy and of gynecologic lesions. The full potential of this new technology is yet to be determined and deserves scientific evaluation.

medicine.medical_specialtyImage qualityMultimodal ImagingMultimodalitySoftwareLight sourceObstetrics and gynaecologyComputer SystemsPregnancyImage Interpretation Computer-AssistedmedicineHumansRadiology Nuclear Medicine and imagingComputer visionDiagnostic Techniques Obstetrical and GynecologicalUltrasonographybusiness.industryEmphasis (telecommunications)UltrasoundImage EnhancementObstetric Labor ComplicationsLight intensityFemaleRadiologyArtificial intelligencebusinessGenital Diseases FemaleSoftwareUltrasound quarterly
researchProduct

Small for gestational age (SGA) neonates show reduced suppressive activity of their regulatory T cells

2009

Little information exists concerning the role of fetal regulatory T cells (Tregs) during intrauterine development. We examined whether complications such as reduced birth weight or the occurrence of preterm labor were associated with deficiencies in the number or in the immunosuppressive activity of Tregs in the fetal circulation. Their total number did not change during normal or complicated pregnancy. In contrast, their level of FoxP3 expression decreased continuously with gestational age and was significantly reduced in the presence of spontaneous term, but not preterm labor. In small for gestational age (SGA) neonates, FoxP3 expression was constantly decreased when compared to age match…

medicine.medical_specialtyImmunologychemical and pharmacologic phenomenaCell SeparationT-Lymphocytes RegulatoryFetusObstetric Labor PrematurePregnancyT-Lymphocyte SubsetsInternal medicinemedicineHumansImmunology and AllergyPregnancyFetusbusiness.industryInfant NewbornGestational ageForkhead Transcription Factorshemic and immune systemsInfant Low Birth WeightFlow Cytometrymedicine.diseaseLow birth weightTolerance inductionEndocrinologyFetal circulationGestationSmall for gestational ageFemalemedicine.symptombusinessClinical Immunology
researchProduct

Response to the comment on "Can stress biomarkers predict preterm birth in women with threatened preterm labor?"

2017

medicine.medical_specialtyObstetric LaborEndocrinology Diabetes and MetabolismMEDLINE03 medical and health sciences0302 clinical medicineEndocrinologyThreatened Preterm LaborObstetric Labor PrematurePregnancymedicineHumans030212 general & internal medicineBiological PsychiatryPregnancyEndocrine and Autonomic SystemsObstetricsbusiness.industrymedicine.diseasePsychiatry and Mental healthStress biomarkersPremature birthPremature BirthFemalebusiness030217 neurology & neurosurgeryBiomarkers
researchProduct

The effects on offspring of premature parturition

2001

The time of parturition defines the length of the intrauterine period of fetal life, a requisite to achieve adequate adaptation to the external environment. Immaturity, a condition whose severity is inversely related to the length of pregnancy, is the main determinant of the increased morbidity and mortality associated with preterm birth. Despite great advances in medical technology and expertise, mainly after the introduction of the neonatal intensive care units, only one- to two-thirds of infants from the subsets with lower birthweight/gestational age reach survival at discharge. Distinct major neurological and sensorial sequelae, including cerebral palsy, retinopathy of prematurity, and …

medicine.medical_specialtyPediatricsBirth weightReproductive technologyFetusObstetric Labor PrematurePregnancyIntensive careInfant MortalityPrevalenceHumansMedicineDisabled PersonsPregnancybusiness.industryObstetricsDeveloped CountriesMortality rateInfant NewbornObstetrics and GynecologyGestational ageRetinopathy of prematuritymedicine.diseaseSurvival AnalysisReproductive MedicinePremature birthFemalebusinessInfant PrematureHuman Reproduction Update
researchProduct