Search results for "Oct"

Molecular mechanisms determining the strength of receptor-mediated intermembrane adhesion

1995

The strength of receptor-mediated cell adhesion is directly controlled by the mechanism of cohesive failure between the cell surface and underlying substrate. Unbinding can occur either at the locus of the specific bond or within the bilayer, which results in tearing the hydrophobic anchors from the membrane interior. In this work, the surface force apparatus has been used to investigate the relationship between the receptor-ligand bond affinities and the dominant mechanism of receptor-coupled membrane detachment. The receptors and ligands used in this study were membrane-bound streptavidin and biotin analogs, respectively, with solution affinities ranging over 10 orders of magnitude. With …

Some reflections on non-contractual obligations in cyberspace considering the Rome II regulation

2014

Internet penetration has created a revolutionary change in people's communication nowadays. By creating immaterial and elusive cyberspace, without borders and limits of communication a three-dimensional territorial concept has been transformed by globalizing social relations and reducing importance of regional or national dimensions. All situations taking place on the Internet also occur somewhere in the reality. Sometimes it is difficult to measure whether the events are random or unrelated to particular events. Technological progress offers new possibilities to change a user's real location either consciously or subconsciously. However, the law is highly territorial in nature. This articl…

Two light sensors decode moonlight versus sunlight to adjust a plastic circadian/circalunidian clock to moon phase

2021

AbstractMany species synchronize their physiology and behavior to specific hours. It is commonly assumed that sunlight acts as the main entrainment signal for ~24h clocks. However, the moon provides similarly regular time information, and increasingly studies report correlations between diel behavior and lunidian cycles. Yet, mechanistic insight into the possible influences of the moon on ~24hr timers is scarce.We studiedPlatynereis dumeriliiand uncover that the moon, besides its role in monthly timing, also schedules the exact hour of nocturnal swarming onset to the nights’ darkest times. Moonlight adjusts a plastic clock, exhibiting <24h (moonlit) or >24h (no moon) periodicity. Abun…

From A Medial Surface To A Mesh

2012

Medial surfaces are well-known and interesting surface skeletons. As such, they can describe the topology and the geometry of a 3D closed object. The link between an object and its medial surface is also intuitively understood by people. We want to exploit such skeletons to use them in applications like shape creation and shape deformation. For this purpose, we need to define medial surfaces as Shape Representation Models (SRMs). One of the very first task of a SRM is to offer a visualization of the shape it describes. However, achieving this with a medial surface remains a challenging problem. In this paper, we propose a method to build a mesh that approximates an object only described by …

Polymeric drug delivery micelle-like nanocarriers for pulmonary administration of beclomethasone dipropionate

2017

In this paper, the potential of novel polymeric micelles as drug delivery systems for Beclomethasone Dipropionate (BDP) administration into the lung is investigated. These nanostructures are obtained starting from α,β-poly(N-2-hydroxyethyl)-D,L-aspartamide (PHEA), which was subsequently functionalized with O-(2-aminoethyl)-O’-methylpolyethylenglycole (PEG2000), ethylenediamine (EDA) and lipoic acid (LA), obtaining PHEA-PEG2000-EDA-LA graft copolymer. Empty and drug-loaded micelles possess adequate chemical-physical characteristics for pulmonary administration such as spherical shape, slightly positive surface charge and mean size of about 200 nm. Besides, BDP-loaded micelles, obtained …

Tīklenes un dzīslenes biezums pacientiem ar obstruktīvo miega apnojas hipopnojas sindromu

2021

Maģistra darbs izstrādāts latviešu valodā, uz 54 lapaspusēm. Tas satur 22 attēlus, 11 tabulas un 76 atsauces uz literatūras avotiem. Darba mērķis: ir nomērīt un salīdzināt tīklenes nervu šķiedra slāņa (RNFL) biezumu, tīklenes divu slāņu kompleksa (ganglion cell layer pluss inner plexiform layer, GCL+) un dzīslenes biezumu makulā (chorioscleras interface, CSI) veseliem cilvēkiem un pacientiem obstruktīvo miega apnojas hipopnojas sindromu. Literatūras pārskatā tika izanalizēta obstruktīvas miega apnojas hipopnojas sindroma ietekme uz tīklenes un dzīslenes strukturālām izmaiņām un iespējamo patoģenēzi. Pētījuma daļā ar okulāro koherences tomogrāfijas instrumentu tika nomērīts tīklenes un dzīsl…

Venom gland and reservoir morphology in the Doryctinae and related braconid wasps (Insecta, Hymenoptera, Braconidae)

1992

Detailed venom reservoir and venom gland intima morphology has been investigated in reprsentatives of 84 genera and 10 subfamilies of Braconidae with particular reference to the Doryctinac, basal cyclostomes and related groups including the Opiinae, Alysiinae and Rogadinae sens. lat. Several new phylogenetically significant characters are described and illustrated. Extcnsivc secretory ductules on the primary venom duct is suggested as a synapomorphy for the subfamilies Braconinac, Doryctinae, Opiinae, Alysiinae and Gnamptodontinae. The presence of two separate venom gland insertions and their position beyond the spiral sculpture of the reservoir are suggested as synapomorphies for the subfa…

Telemedicine the role of the patient-doctor relationship

The aim of this work is to study whether and how the characteristics of the existing relationship between a patient and her/his doctor impact the patient’s propensity to switch to telemedicine. We build a conceptual model which hypothesizes a direct effect of the patient-doctor relationship on the propensity to telemedicine, with the perceived efficacy of the healthcare service as the mediator. To collect data, we used the survey methodology. The results confirm the hypothesis about the positive effects of both a good patient-doctor relationship and the patients’ perceived value on the patients’ propensity to switch to telemedicine.

Evaņģeliskā dogmātika

1939

The ionic tin(IV) complex tri-μ2-methoxy-μ3-oxo-tris[di-tert-butyltin(IV)] tri-μ2-methoxy-bis[tert-butyldimethoxystannate(IV)]

2004

The solid-state of the title compound, [Sn3(C4H9)6(CH3O)3O][Sn2(C4H9)2(CH3O)7], consists of distinct [tBu6Sn3(μ-OCH3)3(μ3-O)]+ cations and [tBu2Sn2(OCH3)4(μ-OCH3)3]− anions, apparently formed as a result of slow hydro­lysis of pure di(tert-butyl)­di­methoxy­stannane, tBu2Sn(OCH3)2. In the monocation, the coordin­ation about the Sn atoms is distorted trigonal bipyramidal, and, in the monoanion, distorted octahedral. The trigonal bipyramidal arrangement induces planarity of the Sn3O4 motif.