Search results for "Oct"
showing 10 items of 3052 documents
Maternal Oct-4 is a potential key regulator of the developmental competence of mouse oocytes
2008
Abstract Background The maternal contribution of transcripts and proteins supplied to the zygote is crucial for the progression from a gametic to an embryonic control of preimplantation development. Here we compared the transcriptional profiles of two types of mouse MII oocytes, one which is developmentally competent (MIISN oocyte), the other that ceases development at the 2-cell stage (MIINSN oocyte), with the aim of identifying genes and gene expression networks whose misregulated expression would contribute to a reduced developmental competence. Results We report that: 1) the transcription factor Oct-4 is absent in MIINSN oocytes, accounting for 2) the down-regulation of Stella, a matern…
Solitary Rectal Ulcer
1979
Solitary ulcers of the rectum may be traumatic in origin and caused by thermometers, occasionally by digital removal of a fecal impaction, or by deviate sexual behavior. Solitary rectal ulcers may also be a manifestation of Crohn’s disease. Very rarely, ectopic gastric mucosa is their cause. For the vast majority of solitary rectal ulcers, the explanation remains unknown. Occasionally, the ulcers are accompanied by localized inflammation of the mucosa within the distal segment of the rectum with edema, erythema, and circumscribed whitish flecks in a thickened bowel wall covered by excessive secretions. The changes are found predominantly in the ventral portion of the rectum, and in contrast…
Characterization of gramicidin A in an inverted micellar environment. A combined high-performance liquid chromatographic and spectroscopic study
1992
We have investigated the conformational adaptability of gramicidin A incorporated into reverse micelles of sodium bis(2-ethylhexyl)sulfosuccinate (AOT)/isooctane/water, a so far unexplored "host" membrane-mimetic model system for this peptide. A high-performance liquid chromatographic strategy previously developed for the study of gramicidin in phospholipid vesicles and normal micelles [Bañó et al. (1989) FEBS Lett. 250, 67; Bañó et al. (1991) Biochemistry 30, 886] has been successfully extended to this system. The method has permitted the separation of peptide conformational species, namely, double-stranded dimers and monomers, and an accurate quantitation of their proportion in the invert…
Novel bifunctional DATA chelator for quick access to site-directed PET 68Ga-radiotracers: preclinical proof-of-principle with [Tyr3]octreotide
2017
Molecular imaging of tumors with the PET radionuclide 68Ga has gained momentum in clinical oncology due to the expanding availability of commercial 68Ge/68Ga-generators in combination with state-of-the-art PET/CT and PET/MRI hybrid imaging systems. Concurrently, interesting peptide-based or small-size vectors have been developed for theranostic use in cancer patients. Owing to the short half-life of 68Ga (t1/2 = 67.7 min) and the sensitivity of many targeting biomolecules, labeling and kit reconstitution in mild conditions allowing for quick access to ready-for-injection PET-tracers are highly desirable. The novel DATA ((6-pentanoic acid)-6-(amino)methy-1,4-diazepinetriacetate) chelator pre…
Receptive Reason: Alexander of Aphrodisias on Material Intellect
2010
AbstractAccording to Alexander of Aphrodisias, our potential intellect is a purely receptive capacity. Alexander also claims that, in order for us to actualise our intellectual potentiality, the intellect needs to abstract what is intelligible from enmattered perceptible objects. Now a problem emerges: How is it possible for a purely receptive capacity to perform such an abstraction? It will be argued that even though Alexander’s reaction to this question causes some tension in his theory, the philosophical motivation for it is a sound one. Rather than a calculation of actualities and potentialities, the doctrine of receptivity is supposed to explain how human beings come to grasp universal…
Quelles nuits, pour quels territoires ?
2015
International audience; Quelles nuits, pour quels territoires ?
Automorphisms of the integral group ring of the hyperoctahedral group
1990
The purpose of this paper is to verify a conjecture of Zassenhaus [3] for hyperoctahedral groups by proving that every normalized automorphism () of ZG can be written in the form () = Tu 0 I where I is an automorphism of ZG obtained by extending an automorphism of G linearly to ZG and u is a unit of (JJG. A similar result was proved for symmetric groups by Peterson in [2]; the reader should consult [3] or the survey [4] for other results of this kind. 1989
Transitive factorizations in the hyperoctahedral group
2008
The classical Hurwitz enumeration problem has a presentation in terms of transitive factor- izationsin the symmetric group. This presentationsuggestsageneralizationfromtypeAto otherfinite reflection groups and, in particular, to type B.W e study this generalization both from ac ombinatorial and a geometric point of view, with the prospect of providing am eans of understanding more of the structure of the moduli spaces of maps with an S2-symmetry. The type A case has been well studied and connects Hurwitz numbers to the moduli space of curves. W ec onjecture an analogous setting for the type B case that is studied here. 1I ntroduction Transitive factorizations of permutations into transposit…
POLYNOMIAL GROWTH OF THE*-CODIMENSIONS AND YOUNG DIAGRAMS
2001
Let A be an algebra with involution * over a field F of characteristic zero and Id(A, *) the ideal of the free algebra with involution of *-identities of A. By means of the representation theory of the hyperoctahedral group Z 2wrS n we give a characterization of Id(A, *) in case the sequence of its *-codimensions is polynomially bounded. We also exhibit an algebra G 2 with the following distinguished property: the sequence of *-codimensions of Id(G 2, *) is not polynomially bounded but the *-codimensions of any T-ideal U properly containing Id(G 2, *) are polynomially bounded.
A Star-Variety With Almost Polynomial Growth
2000
Abstract Let F be a field of characteristic zero. In this paper we construct a finite dimensional F -algebra with involution M and we study its ∗ -polynomial identities; on one hand we determine a generator of the corresponding T -ideal of the free algebra with involution and on the other we give a complete description of the multilinear ∗ -identities through the representation theory of the hyperoctahedral group. As an outcome of this study we show that the ∗ -variety generated by M , var( M , ∗ ) has almost polynomial growth, i.e., the sequence of ∗ -codimensions of M cannot be bounded by any polynomial function but any proper ∗ -subvariety of var( M , ∗ ) has polynomial growth. If G 2 is…