Search results for "Oct"
showing 10 items of 3052 documents
Les politiques d’excellence influencent-elles la production doctorale en France ?
2023
L'attractivité des programmes d’enseignement supérieur est souvent présentée comme un levier pour développer le potentiel de recherche et d'innovation dans les pays développés. En France, deux politiques d’excellence ont été développées dans le cadre du programme des investissements d’avenir (PIA) : les IdEx (initiatives d'excellence) et les Labex (laboratoires d'excellence). Ces programmes visaient notamment à créer des universités françaises comparables aux meilleures universités des autres pays, en favorisant la construction d'une politique intégrée de recherche, de formation et de valorisation. Ils pouvaient par exemple permettre d’attirer des étudiants de haut niveau et des chercheurs …
La professionnalisation du doctorat : vers une segmentation de la formation doctorale et des parcours des docteurs ?
2020
Borrowing from Pierre Bourdieu's theoretical corpus, the thesis analyzes the process of professionalization of the doctorate that took place in France from the mid-2000s. The main objectives of the movement are to improve the professional future of PhDs, to reduce job insecurity at the beginning of their careers and to promote their integration into companies. At a time when the professional integration of higher education graduates and the performance of innovation systems are major challenges for national policies, the future of PhDs is characterized by a high degree of job insecurity in public research jobs and poor integration into companies. As a result, the added value of the PhD on t…
Latvijas veselības aprūpes institūciju un personāla gatavība katastrofu pārvaldīšanā
2017
Ievads: Pēdējo desmit gadu laikā pasaulē visu veidu katastrofu skaits ir ievērojami palielinājies, kā arī ievērojami ir pieaudzis cietušo cilvēku skaits. Līdz ar to slimnīcām un ārstiem jābūt gataviem risināt ārkārtas situācijas. Šis pētījums novērtē katastrofu pārvaldības sagatavotības līmeni Latvijas veselības aprūpes iestādēs un ārstu vidū. Materiāli un metodes: Materiāli tika apkopoti laika posmā no 2016. gada oktobra līdz 2017. gada februārim. 21 Latvijas slimnīcu administrācijai vai neatliekamās palīdzības vadītājiem tika dota pielāgota aptauja - Slimnīcas ārkārtas situāciju gatavības kontrollapa (Pasaules Veselības organizācijas Eiropas Reģionālā biroja, 2011), kas ietver četras galv…
Biogenic amine levels, reproduction and social dominance in the queenless ant Streblognathus peetersi
2006
Social harmony often relies on ritualized dominance interactions between society members, particularly in queenless ant societies, where colony members do not have developmentally predetermined castes but have to fight for their status in the reproductive and work hierarchy. In this behavioural plasticity, their social organisation resembles more that of vertebrates than that of the "classic" social insects. The present study investigates the neurochemistry of the queenless ant species, Streblognathus peetersi, to better understand the neural basis of the high behavioural plasticity observed in queenless ants. We report measurements of brain biogenic amines [octopamine, dopamine, serotonin]…
Reversible Doctrine : essays on the unstable discipline of architectural design
2016
Il libro affronta il tema dellareversibilità della disciplina della progettazione architettonica. E' basato sull'assunto che il pensiero intorno all'architettura sia complesso e instabile. Lo studio spazia tra i poli estremi del pensiero architettonico. Da un lato mira a descrivere la reversibilità dell'architettura e, dall'altro lato, riconsidera criticamente alcuni fondamentali del pensiero architettonico. In realtà nonostante l'apologia per l'instabilità il libro si focalizza su alcuni "strumenti del pensiero" ed il modo con il quale sono stati usati all'interno della teoria dell'architettura. In questa vicenda l'impatto del pensiero cartesiano sul modo di intendere il progetto di archit…
Rapid in vitro test to predict ocular tissue permeability based on biopartitioning micellar chromatography.
2003
The drug permeability prediction across the ocular tissues is important in the development of new drugs and drug delivery strategies. Physicochemical characteristics of drugs, mainly acid-base character, hydrophobicity and the molecular size determine both their transport across the eye tissue barriers and their retention in biopartitioning micellar chromatography (BMC). An in vitro model able to describe and predict the whole cornea drug permeability is proposed. The model uses the retention of drugs in BMC and molecular weight (MW) as predictive variables. The relationships between drug retention data in BMC and their bibliographic permeability values in stroma, epithelium-plus-stroma and…
Solid lipid nanoparticles containing tamoxifen characterization and in vitro antitumoral activity.
2005
Solid lipid nanoparticles (SLNs) containing tamoxifen, a nons- teroidal antiestrogen used in breast cancer therapy, were prepared by microemulsion and precipitation techniques. Tamoxifen loaded SLNs seem to have dimensional properties useful for parenteral administration, and in vitro plasmatic drug release studies demon- strated that these systems are able to give a prolonged release of the drug in the intact form. Preliminary study of antiproliferative ac- tivity in vitro, carried out on MCF-7 cell line (human breast cancer cells), demonstrated that SLNs, containing tamoxifen showed an antitumoral activity comparable to free drug. The results of char- acterization studies and of in vitro …
Comparative Study of the Mechanical Unfolding Pathways of α- and β-Peptides
2015
Using molecular simulations, we analyze the unfolding pathways of various peptides. We compare the mechanical unfolding of a β-alanine's octamer (β-HAla8) and an α-alanine's decamer (α-Ala10). Using force-probe molecular-dynamics simulations, to induce unfolding, we show that the 3(14)-helix formed by β-HAla8 is mechanically more stable than the α-helix formed by α-Ala10, although both structures are stabilized by six hydrogen bonds. Additionally, computations of the potential of mean force validate this result and show that also the thermal stability of the 3(14)-helix is higher. It is demonstrated that β-HAla8 unfolds in a two-step fashion with a stable intermediate. This is contrasted wi…
La mobilité internationale des diplômés de doctorat en France
2013
Cette communication porte sur les déterminants de la mobilité internationale de 400 jeunes diplômés d'un doctorat en France entre 2003 et 2008, dont la moitié se trouve encore à l'étranger, plus de six ans après l'obtention du doctorat. Sont notamment examinés l'impact des facteurs personnels, professionnels et scientifiques dans les décisions successives de mobilités après la fin de la thèse. Les résultats montrent que les motivations d'un départ à l'étranger s'expliquent principalement par la difficulté de trouver un emploi sur le marché du travail français. Les choix d'une longue expatriation sont plus éclatés et plus complexes à démêler. En revanche, le retour en France après une longue…
Analysis of documentary and terminological needs of doctors and medical translators as a basis for the development of a next-generation multilingual …
2014
En el presente trabajo se plantea el diseño de un recurso lexicográfico multilingüe orientado a médicos y traductores médicos. En la actualidad, no existe ningún recurso que satisfaga a ambos colectivos por igual, debido a que estos poseen necesidades muy diferentes. Sin embargo, partimos de la premisa de que se podría crear una herramienta única, modular, adaptable y flexible, que responda a sus diversas expectativas, necesidades y preferencias. Se parte para ello de un análisis de necesidades siguiendo el método empírico de recogida de datos en línea mediante una encuesta trilingüe. The objective of this study is to develop a multilingual lexicographical resource aimed at doctors and medi…